Investigation of differential immune status among cancer patients and development of personalized cancer therapy by combining immunomodulation
Investigation of differential immune status among cancer patients and development of personalized cancer therapy by combining immunomodulation
批准号:
26221005
负责人:
KAWAKAMI Yutaka
金额:
$124.88万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (S)
财政年份:
2014
资助国家:
日本
项目状态:
已结题
起止时间:
2014-05-30 至 2019-03-31
中文摘要
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CD44-highly expressing subpopulation in colorectal cancer shows strong resistance to tumor specific CTL by producing higher levels of a protease inhibitor, a possible immunosuppressive molecule
结直肠癌中 CD44 高表达的亚群通过产生更高水平的蛋白酶抑制剂(一种可能的免疫抑制分子),表现出对肿瘤特异性 CTL 的强大抵抗力
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[Miyauchi Tsubasa, Yaguchi Tomonori, Kawakami Yutaka]
通讯作者:
Kawakami Yutaka
Macrophage migration inhibitory factor(MIF) supports the cell proliferation in brain tumor-initiating cells.
巨噬细胞迁移抑制因子(MIF)支持脑肿瘤起始细胞的细胞增殖。
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[Shigeki Ohta, Raita Fukaya, Tomonori Yaguchi, Yumi Matsuzaki, Eiji Sugihara, Hideyuki Saya, Yutaka Kawakami, Takeshi Kawase, Kazunari Yoshida, Masahiro Toda, Hideyuki Okano.]
通讯作者:
Hideyuki Okano.
症例ごとの免疫状態評価に基づいた個別化がん免疫療法
基于每个病例的免疫状态评估的个体化癌症免疫治疗
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[河上裕, 藤田知信, 谷口智憲]
通讯作者:
谷口智憲
ヒト大腸癌で、抗腫瘍細胞傷害性T細胞に対して耐性である分画を定義する細胞表面マーカーの探索
寻找定义人类结直肠癌中抗肿瘤细胞毒性 T 细胞抵抗分数的细胞表面标记
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[宮内翼, 谷口智憲, 藤田知信, 河上裕]
通讯作者:
河上裕
第5回日本免疫学会ヒト免疫研究賞「ヒトがん免疫病態の解明による癌免疫療法の開発」
第5届日本免疫学会人类免疫学研究奖“通过阐明人类癌症免疫病理学开发癌症免疫疗法”
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[○桑原泰隆, 寒河裕人, 山下弘巳, 武田健太,神岡純,小幡利顕,大塚朋廣,中島峻,マシュー・デルベック,天羽真一,米田淳,野入亮人,菅原烈,小寺哲夫,小田俊理,樽茶清悟, 河上裕]
通讯作者:
河上裕
共 221 条
Systematic analysis of cellular signaling involved in the melanoma induced immunosuppression
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批准号:25670506
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
-
财政年份:2013
-
负责人:KAWAKAMI Yutaka
-
依托单位:
Development of effective immunotherapy by combining interventions on key points in the anti-tumor immune network
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批准号:23240128
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$31.37万
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财政年份:2011
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负责人:KAWAKAMI Yutaka
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依托单位:
Investigation of roles of miRNA in the immunosuppression and clinical use for patients with melanoma
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批准号:23659554
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2011
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负责人:KAWAKAMI Yutaka
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依托单位:
Development of effective immunotherapy by combining methods to restore immunocompetence of cancer patients
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批准号:19390355
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.15万
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财政年份:2007
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负责人:KAWAKAMI Yutaka
-
依托单位:
Development of immunotherapy based on the identification of tumor antigens
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批准号:17016070
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$34.69万
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财政年份:2005
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负责人:KAWAKAMI Yutaka
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依托单位:
Development of new diagnostic and immunotherapeutic methods for patients with cancer
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批准号:14104013
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$70.14万
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财政年份:2002
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负责人:KAWAKAMI Yutaka
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依托单位:
Systematic isolation of genes encoding candidate proteins for human melanoma antigens using serial analysis of gene expression (SAGE) and EST database
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批准号:12470180
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.22万
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财政年份:2000
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负责人:KAWAKAMI Yutaka
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依托单位:
Development of diagnositic and therapeutic methods using frameshift mutated peptides for colorectal cancers with microsatellite instability
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批准号:12557109
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.45万
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财政年份:2000
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负责人:KAWAKAMI Yutaka
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依托单位:
Isolation of human melanoma antigens recognized bt T cells for development of immunotherapy and gene therapy
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批准号:10557083
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.7万
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财政年份:1998
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负责人:KAWAKAMI Yutaka
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依托单位:
Isolation of human tumor antigens recognized by antibodies for development of immunotherapy and gene therapy
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批准号:10470264
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.38万
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财政年份:1998
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负责人:KAWAKAMI Yutaka
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依托单位:
海外基金