Refined Methods for Inference of Metazoan Phylogeny Using Mitochondrial Genome Arrangement Data

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Mitochondrial genomes have been a particularly fruitful data set for phylogenetic reconstructions. Due to their limited size and the availability of a large number of informative data sets, they are particularly interesting for the reconstruction of deep metazoan phylogeny. We aim to contribute to a well-supported phylogenetic tree of the metazoa by applying new evolutionary models and phylogenetic methods as well as by acquiring and analyzing new data. We propose to establish a refined model of mitochondrial genome evolution based on multiple genome rearrangements and correspondingly to develop efficient algorithms that are able to infer phylogenies from large data sets. The second major part of our project deals with analyzing metazoan mitochondrial genome sequences, aiming to resolve open questions concerning the phylogeny of the Metazoa.