Refined Methods for Inference of Metazoan Phylogeny Using Mitochondrial Genome Arrangement Data

使用线粒体基因组排列数据推断后生动物系统发育的精细方法

• 批准号: 5454375
• 负责人: Professor Dr. Bernd Schierwater
• 金额: --
• 依托单位: Institut für Tierökologie
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2005
• 资助国家: 德国
• 起止时间: 2004-12-31 至 2007-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/5454375?language=en
• 关键词: Refined; Methods; Inference; Metazoan; Phylogeny

Mitochondrial genomes have been a particularly fruitful data set for phylogenetic reconstructions. Due to their limited size and the availability of a large number of informative data sets, they are particularly interesting for the reconstruction of deep metazoan phylogeny. We aim to contribute to a well-supported phylogenetic tree of the metazoa by applying new evolutionary models and phylogenetic methods as well as by acquiring and analyzing new data. Using two established methods for infering phylogenies as a starting point, namely multiple genome rearrangements as well as circular alignments, we propose to establish a refined model of mitochondrial genome evolution and correspondingly to develop efficient algorithms that are able to infer phylogenies from large data sets. A second major part of our project deals with acquiring and analyzing mitochondrial genome sequences, aiming to resolve open questions concerning the evolutionary roles and relationships between certain taxa such as Porifera, Placozoa, Cnidaria and Bilateria (including Hemichordata, Echinodermata and Chordata).

线粒体基因组是用于系统发育重建的特别富有成效的数据集。由于其有限的大小和大量信息数据集的可用性，它们对于重建深层后生动物系统发育特别有趣。我们的目标是通过应用新的进化模型和系统发育方法以及获取和分析新数据，为后生动物的系统发育树做出贡献。使用两种已建立的推断系统发育的方法作为起点，即多重基因组重排和循环比对，我们建议建立线粒体基因组进化的精细模型，并相应地开发能够从大数据集中推断系统发育的有效算法。我们项目的第二个主要部分涉及获取和分析线粒体基因组序列，旨在解决有关某些类群（如多孔动物门、扁动物门、刺胞动物门和双边动物门（包括半索动物门、棘皮动物门和脊索动物门））之间的进化作用和关系的悬而未决的问题。