INFORMATION PROCESSING IN CEREBELLAR FLOCCULUS FUNCTIONAL ZONE

研究了警觉猫在光动力学反应（OKR）过程中眼动与小脑小叶中间区浦肯野细胞时间单峰频率（SS）的相关性。通过眼加速度（平均系数为0.076 spike /s / deg/s2）、速度（5.19 spike /s / deg/s）、位置（-2.89 spike /s / deg/s）和偏置（平均为35.8 spike /s）的线性加权叠加，可以很好地重建给定时间延迟（平均为11 ins）的时间过程，确定系数为>.7，并估计了各分量对回归的贡献大小，发现了三种细胞类型：速度-位置-加速度（VPA）类型（n=19），速度、位置和加速度分量的贡献显著（P < 0.05）；速度-位置（VP）型（n=9）、速度和位置分量显著；速度-加速度（VA）型（n=2），速度和加速度分量显著。使用5度/秒刺激速度下的一组系数，成功地重建了更高（10、20和40度/秒）刺激速度下的SS率，表明了模型的普遍性。在OKR过程中，ss发射过程中编码的眼位信息是相对的，而不是绝对的，即无论初始眼位如何，位置移动的大小都会影响射击速率的变化。结果表明：1)在短时间水平空燃过程中，瞬态发射频率编码的速度和加速度信息分别用于控制黏力和惯性力；2)空燃中编码的位置信息不足以用于控制空燃过程中的弹性力。

We investigated correlation between the eye movement and temporal simple-spike (SS) frequency of the Purkinje cell in the cerebellar flocculus middle-zone during optokinetic response (OKR) in alert cats. Time course of the temporal SS-rate at a given time delay (mean, 11 ins) was well reconstructed with coefficient of determination > 0.7 by a linear weighted superposition of the eye acceleration (mean coefficient, 0.076 spikes/s per deg/s2), velocity (5.19 spikes/s per deg/s), position (-2.89 spikes/s per deg), and bias (mean, 35.8 spikes/s), Magnitude of the contribution of each component to the regression was estimated, and three cell types were found : Velocity-Position-Acceleration (VPA) type (n=19), contribution of velocity, position, and acceleration components is significant (P < 0.05) ; Velocity-Position (VP) type (n=9), velocity and position components are significant ; Velocity-Acceleration (VA) type (n=2), velocity and acceleration components are significant. Using a single set of the coefficients for 5 deg/s stimulus velocity, the SS rate during higher (10, 20, and 40 deg/s) stimulus velocities were successfully reconstructed, suggesting generality of the model. The eye-position information encoded in SS-firing during OKR is relative but not absolute in the sense that the magnitude of the position shift contributes to the firing-rate change regardless of the initial eye-position. It is concluded that 1) the temporal SS-firing frequency in the cat middle-zone encodes the velocity and acceleration information for controlling the viscosity- and inertia-forces, respectively, during short-duration horizontal OKR and 2) the position information encoded in the SS-firing is not sufficient for controlling the elastic force during] OKR.