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Blood Flow Imaging Technique for Intravascular Ultrasound

血管内超声血流成像技术

基本信息

批准号：
08680920
负责人：
KUDO Nobuki
金额：
$ 1.54万
依托单位：
HOKKAIDO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1996
资助国家：
日本
起止时间：
1996 至 1997
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08680920/
关键词：
Medical ultrasound Intravascular Ultrasound Blood flow measurement Correlation RF signal Atheroma Vascular lumen

项目摘要

1.RF echo processingWe developed a new time domain correlation technique for detecting displacement and velocity vectors. The technique is based on calculation of the correlation between RF echo detected by a single transducer at a fixed repetition rate. Relation between the velocity vector and correlation was derived theoretically. Advanced RF signal processing techniques for evaluation of structure and charactor of biological tissue were also discussed.2.Measurement system>>Transducers for IVUSSmall transducers (1.2mm * 0.8mm) which can be used in the IVUS catheter were developed. Improvement of spatial resolution and speckle reduction in the B-mode image were discussed.>>Data acquisition and processing systemRF echo signal of the 16 sequential radial scan images is digitized into a 4 Mbyte digital data and a correlation image is processed in several minutes using personal computer. A blood flow phantom was also diveloped for in vitro experiments.3.Experimental evaluation>>Measurement of flow velocity (1-D distribution)In vitro experiments to measure the one-dimensional distribution of the flow velocity in the flow phantom were carried out. The experimental results demonstrated the practicability of the flow velocity measurement in the IVUS using the correlation technique.>>Detection of vascular lumen (2-D imaging)Extension of the correlation technique to the radial scan image was discussed. In this case, it is difficult to measure the flow velocity using correlation technique. However, still it is possible to get the information whether it flows or not. In vitro experiment showed that the vascular lumen was clearly identified in the radial scan image using the correlation technique.

1.我们提出了一种新的时域相关技术来检测位移和速度矢量。该技术是基于计算在固定重复率下由单个换能器检测到的射频回波之间的相关性。从理论上推导了速度矢量与相关系数的关系。讨论了射频信号处理技术在生物组织结构和特性评价中的应用。开发了可用于IVUS导管的小型换能器（1.2mm * 0.8mm）。讨论了b模图像空间分辨率的提高和散斑的降低。数据采集与处理系统将16张顺序径向扫描图像的射频回波信号数字化为4mbyte的数字数据，并利用个人计算机在几分钟内处理出一幅相关图像。血流模体也被开发用于体外实验。实验评价>>流速测量（一维分布）体外实验测量流速在流动模体内的一维分布。实验结果证明了相关技术在IVUS中测量流速的实用性。血管腔检测（二维成像）讨论了相关技术在径向扫描图像中的推广。在这种情况下，用相关技术测量流速是困难的。然而，无论信息是否流动，都有可能获得信息。体外实验表明，利用相关技术在径向扫描图像中可以清晰地识别出血管腔。