Preparation and Biomechanics of High-performance Artificial Bones Containing

使用dilune NaOH solution的bioresorbable poly-L-lactic acid （PLA） and high strength（Ca）-Ca（PO-D23-D2）-D22-D2 fibers （CPF） treated with dilune NaOH solution。PLA是由使用甲基氯酰氯与纤维混合而成的。在混合物干燥后，它在180℃下均匀地在40兆帕的压力下按压，并在含有PLA复合材料的制造中制造出结果。在弯曲强度中，几乎没有退化，即使在纤维的较大数量（[近似等于] 50 wt%）被引入时，弹性的模块也变得非常有效，因为纤维含量增加了。该PLA复合物具有> 5GPa的弹性模块，类似于当纤维含量超过35 wt%时，天然骨骼被发现可以准备好。对复合材料的弯曲测试表明，非常高的能量被消耗在他们的碎片中，而这种碎片过程被认为是正确的。 ... More p一步一步，甚至超过了最大压力。在PLA样本在90天的模拟体内流体（SBF）中浸泡后，最大压力被极大地消除，并且该特殊显示出的典型小碎片与传统陶瓷相似。从PLA的水解中硬化起源，支持在弹性模量中抑制材料的降解，即使最大压力也被降解。PLA-composite含有35%的CPF显示了即使在90天后的发酵中，在控制PLA的情况下也有特征性的分形模式。PLA工业的氢氧化物在复合物中的严重降解也将被转换成SBF中的砖材料，如没有CPF的PLA样品。However，自从复合材料中的CPF可以共享应用负载完全成功，即使是在沉积后，材料显示了非灾难性的缺陷。CPF的混合将PLA作为一个基质相位具有很大的优势，因为弹性模块的价值得到了改善，以接近自然骨骼和材料在湿环境中的硬度下降相对受到限制。PLA复合物的机械性质是预期的，以满足某些应用程序的生物机械要求，如骨骼板或骨骼断裂的临时内部固定。Less（低）

Novel biomaterials for application to artificial bone with modulus of elasticity close to that of natural bone were prepared using bioresorbable poly-L-lactic acid (PLA) and high strength β-Ca(POィイD23ィエD2)ィイD22ィエD2 fibers (CPF) treated with dilune NaOH solution. PLA dissolved by using methylene chloride was mixed with the fibers. After drying the mixture, it was hot-pressed uniaxially under a pressure of 40 MPa at 180℃, resulting in fabrication of a PLA-composite containing CPF. Almost no degradation in the bending strength was observed even when a large amount of the fibers (【approximately equal】50 wt%) was introduced, and the modulus of elasticity was increased effectively with increasing the fiber content. The PLA-composite with modulus of elasticity of >5 GPa similar to that of natural bone was found to be prepared when the fiber content was over 35 wt%. The bending test of the composites showed that very high energy is consumed for their fracture and that the fracture proceeds ste … More p by step, even beyond the maximum stress.After the PLA sample was soaked in simulated body fluid (SBF) for 90 days, the maximum stress was decreased extremely and the specimen showed typical brittle fracture similar to that of conventional ceramics. Hardening originated from hydrolysis of PLA is supported to suppress degradation of the materials in modulus of elasticity, although the maximum stresses are decreased. The PLA-composite containing 35% CPF showed the characteristic fracture pattern even after the soaking for 90 days in control to that PLA. Hydrolysis of PLA induces serious degradation in the composite would be also converted into a brittic material by the soaking in SBF as well as the PLA sample without CPF. However, since CPF in the composite can share an applied load successfully, the material shows non-catastrophic fracture even after the soaking. Hybridization of CPF into PLA as a matrix phase has great advantages that modulus of elasticity is improved to the value close to that of natural bone and that degradation of the material in toughness in a wet environment is relatively restricted. The mechanical properties of the PLA composites are expected to meet the biomechanical requirements of some applications such as bone plates or temporary internal fixation of bones broken damaged. Less