Application of silver-inorganic anti-microbial reagent for prosthodontic field

研究银系无机抗菌剂(离子纯净剂和NOBARON抗菌剂)对口腔微生物的影响。对变形链球菌的最低抑菌浓度(MIC)分别为7.5 mg/ml和1.3 mg。抑菌作用为抑菌作用。结果表明：1.含有两种抗菌剂的树脂平板对平板上的微生物有明显的抑制作用。NOBARON‘TM对白色念珠菌的最低抑菌浓度为500µg/ml，对念珠菌的抑菌作用为念珠菌，含5wt%NOBARON的义齿印迹培养法可明显减少念珠菌的数量。3.1)3种涂层材料(429R、740和光亮剂)在自固化丙烯酸树脂上的接触角分别为37.8度、28.9度和27.9度，比重分别为1.00、1.04和1.07。光亮剂^&lt；TM&gt；在三种材料中表现出较高的诺普硬度。在元素分析方面，含有抗菌剂的增白剂比自固化丙烯酸树脂具有更高的银强度。2)抗菌剂(离子纯净剂和NOBARON抗菌剂)对粘性酵母菌的MIC分别为2.5 mg/ml和1.3 mg/ml，含抗菌剂的抗菌剂比其他涂层材料具有更强的抗菌效果。

The effect of silver-inorganic anti-microbial reagent (ION PURE^<TM> and NOBARON^<TM>) on oral microorganisms were examined.1. Minimam inhibitory concentration (MIC) of anti-microbial reagent (ION PURE^<TM> and NOBARON^<TM>) for S.mutans was 7.5mg/ml and1.3mg. The antimicrobial action was bacteriostatic one. The resin plate thatcontaining both anti-microbial reagent showed remarkably reduced the microorganisms on its plate.2. MIC of NOBARON'TM for C.albicans was 500 mug/ml, and the bacterial action was candidacidal one.Denture containing 5wt% NOBARON^<TM> showed a remarkable decrease in the amount of Candida coloniesby imprint culture method.3.1) The contact angle of three coating materials (429R,740 and Brightener^<TM>) was 37.8 degree, 28.9 degree and 27.9 degree on self- curing acrylic resin, and that specific gravity was 1 .00, 1.04 and 1.07. Brightener^<TM> showed high knoop hardness within three material. For elementary analysis, Brightener^<TM> containing anti-microbial reagent has more Ag intensity than thats of self-curing acrylic resin.2) MIC of anti-microbial reagent (ION PURE^<TM> and NOBARON^<TM>) for A.viscosus was 2.5mg/ml and 1.3mg/ml. Brightener^<TM> containing the reagent has more anti-microbial effect than other coating materials.