Establishment of Systems based on Biomechanical Analysis for Cleft Palate Treatment

基于生物力学分析的腭裂治疗系统的建立

• 批准号: 09470475
• 负责人: SHIBASAKI Yoshinobu
• 金额: $ 3.71万
• 依托单位: Showa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09470475/
• 关键词: Cleft Lip Palate; Finite Element Analysis; Computed Tomographic; Ultrasonic Diagnostic Analysis; Biomechanics

In cleft palate patients, it is well recognized that their dento-maxillo facial skeletons and masticatory systems demonstrate severe deformity and malfunctions. Complexity and difficulty of orthodontic treatment was caused on these morphological and functional characteristics. For further understanding of treatment effectiveness and establishment of considerable procedure, we need a biomechanical analysis of our treatment. Iii addition, evaluating bone mineralization of the maxilla has important clinical implications. Moving teeth orthodontically and/or expansion of dental arch depended upon the level of bone mineralization within the alveolar bone. In this study, we proposed some methods which integrate morphological measurement, functional evaluation and mechanical analysis. New computational software programs were developed. Individual digital data derived from CT scanning and measurement of cast model were used for analysis. Patient specific Finite Element Model was constructed from CT data. Mechanical properties (i.e., Young's modulus) were evaluated using x-ray attenuation value (i.e., GT number), structural properties were adjusted by coordinate transformation method. Bone density distribution and biomechanical behavior under palatal expansion and chin cap therapy were determined by our new system. The results showed that the normal subjects had a bilaterally symmetrical distribution of regions with high shear stress. However in cleft palate patient, altered bone density distribution and displacement by expansion depend on density value were found. These computer-assisted programs can be used to derive clinically useful information in individual subjects.

在腭裂患者中，众所周知，他们的牙颌面部骨骼和咀嚼系统表现出严重的畸形和功能障碍。这些形态和功能特征导致了正畸治疗的复杂性和难度。为了进一步了解治疗效果并建立相当的程序，我们需要对治疗进行生物力学分析。 III 此外，评估上颌骨的骨矿化具有重要的临床意义。正畸移动牙齿和/或牙弓扩张取决于牙槽骨内的骨矿化水平。在本研究中，我们提出了一些结合形态测量、功能评估和力学分析的方法。新的计算软件程序被开发出来。来自 CT 扫描和铸型模型测量的单独数字数据用于分析。根据 CT 数据构建患者特定的有限元模型。使用X射线衰减值（即GT数）评估机械性能（即杨氏模量），通过坐标变换方法调整结构性能。我们的新系统确定了腭扩张和下巴帽治疗下的骨密度分布和生物力学行为。结果显示，正常人的高剪应力区域呈双侧对称分布。然而，在腭裂患者中，发现骨密度分布发生改变，并且扩张引起的位移取决于密度值。这些计算机辅助程序可用于获取个体受试者的临床有用信息。