Data-driven fitting for the next generation of prosthetic sockets

Radii的动机是需要改善全球1.7亿截肢患者的假肢装配。这对患者来说是当务之急：适配的假肢插座是实现移动性和参与社会的决定性因素；对于临床：随着假肢需求的增加，成本负担增加，因此需要支持假肢医生实现完美的插座匹配，更快，更少的排斥。假肢插座连接残肢和假肢部件。无论组件多么先进，如果插座的形状或大小不正确，或者压力分布与用户的需求不匹配，肢体就完全没有用了。由于患者肢体形状、软组织僵硬和局部对负荷的耐受性不同，这些插座的设计很复杂。排斥率为31%。自2014年以来，南安普顿大学的研究人员在Opcare和患者等提供者的指导下，开发出了满足患者和临床需求的技术。Radii Devices正在将这项技术转化为临床。该项目将开发一种革命性的系统，以支持假体插座设计中的假肢医生，用数据和人工智能支持复杂的矫正过程，以实现更好的设计，以实现完美、更快、更少的患者预约。创新包括：*技术：第一个在插座设计过程中提供数据驱动支持的解决方案，能够设计出充分利用尖端3D打印技术的复杂设备。*科学：由世界上最大的插座设计、肢体形状和结果测量数据集支持--最初为1000个，部署后增加。*商业：一个完全可互操作的系统，与任何数字形状捕获和制造方法兼容，这些方法可以获得许可并整合到世界各地的临床路径中。医疗保健方面的挑战是巨大的，英国NHS每年进行7000例截肢手术，成本负担为6000万GB，美国每年有18.5万例截肢手术。随着人口老龄化和糖尿病发病率的上升，挑战越来越大。Radii的创新将通过以下方式应对医疗保健挑战并提供社会经济影响：*通过提供预测性人工智能模型，使修复师能够设计更好的适配插座，释放数据的潜力，以支持实现更快的完美适配。*减少适配时间。*降低拒绝率，降低改装成本。*每个诊所每年节省约20万GB。*通过改善舒适性并使其能够充分参与社会，改善患者的结果和生活质量。

Radii is motivated by the need to improve the fitting of prosthetic limbs for the 170m people worldwide with amputations. This is an urgent priority for patients: a well-fitting prosthetic socket is the determining factor in enabling mobility and participation in society; and for the clinic: with increasing demand for prosthetic limbs, increasing cost burden, and resulting need to support prosthetists to achieve perfect socket fit, faster, with fewer rejections.The prosthetic socket interfaces between the residual limb and the prosthetic componentry. However advanced the componentry, if the socket is the wrong shape or size, or the pressure distribution doesn't match the user's needs, the limb will be completely useless. These sockets are complex to design due to variability in patient limb shape, soft tissue stiffness and regional tolerance to load. Rejection rates are 31%.Since 2014, University of Southampton researchers have developed technology to meet the patient and clinic need, guided by input from providers including Opcare, and patients. Radii Devices are translating this technology to the clinic.This project will develop a revolutionary system to support prosthetists in the design of prosthetic sockets, supporting the complex rectification process with data and AI to enable better designs for perfect fit, faster, with fewer patient appointments.Innovations include:* Technical: the first solution to provide data-driven support in the socket design process, capable of designing complex devices which fully utilise cutting-edge 3D printing technologies.* Scientific: powered by the world's largest dataset of socket designs, limb shapes, and outcome measures -- initially 1000, increasing post-deployment.* Commercial: a fully interoperable system, compatible with any digital shape capture and manufacturing method, which can be licenced and integrated into clinical pathways worldwide.The healthcare challenge is sizeable, with 7,000 amputations performed annually by NHS England, with a £60m cost burden, and 185,000 amputations annually in the US. The challenge is growing with ageing populations and rising diabetes incidence.The Radii innovation will meet the healthcare challenge and offer socio-economic impact by:* Enabling prosthetists to design better fitting sockets by providing predictive AI models, unlocking the potential of data to support achievement of perfect fit, faster.* Reducing time to fit.* Reducing rejection rates and reducing costs of refits.* Offering savings of ~£200k/year per clinic.* Improving patient outcomes and quality of life, with improved comfort and enabling full participation in society.