Molecular System Designing for Capillary Electrophoresis

您的位置：知道173>您的位置：知道173>（1）离子流动性是由电泳缓冲液解决方案中的离子相互作用控制的;一种聚合物电解质（如聚二烯基二甲基氯化铵）的添加被发现对聚氨基甲酸酯的离子金属凝胶、EDTA、Quin 2和HBED复合体的精细分离产生了很大影响。（2）聚氨基羧基配体持有苯甲酸Moieties是sought ;对HBED的三重金属离子的CE选择是演示和二溴衍生物，Bry D22-D-2 HBED是准备的，并与Fe（III）离子反应是测试的。（3）苯二胺的独特选择性-N，N，N'，N'-四乙酸酯向Ca（II）离子被发现。（4）金属配体功能的一种新颖类， Thiacalix[4]阿仑被用于金属CE分析;硫醚原子的选择性氧化方法与四个苯酚Moieties首次报道。这种无端地扩展了Thiacalix的金属选择性控制[4]arenes通过生成硫醚和硫氧化物衍生物。

The aim of this research project is the exploitation of a 'chemical system' approach to novel CE separation modes for metal complexes via a better understanding of the underlying solution chemistry of the CE separation.(1) Ionic mobilities are controlled by ion-ion interactions in electrophoretic buffer solutions ; an addition of polymer electrolyte such as poly(diallyldimethyl ammonium chloride) was found to be very effective for the fine separation of anionic metal chelates of polyaminocarboxylates, EDTA, Quin 2, and HBED complexes.(2) Polyaminocarboxylate ligands possessing phenolate moieties were sought ; the CE selectivity of HBED towards trivalent metal ion was demonstrated and a dibromo derivative, BrィイD22ィエD2HBED was prepared and the reaction with Fe(III) ion was examined.(3) The unique selectivity of phenylenediamine-N,N,N',N'-tetraacetate towards Ca(II) ion was found.(4) A novel class of metal-ligating functions, thiacalix[4]arenes are exploited for the metal CE analysis ; The selective oxidation methods for the sulfur atoms which is linking four phenol moieties were first reported. This doubtless expands the metal selectivity control of the thiacalix[4]arenes via the production of the sulfone and sulfoxide derivatives.