Randomised controlled trial of Vinehealth digital health cancer solution: Covid-19 additional support

Vinehealth 数字健康癌症解决方案的随机对照试验：Covid-19 额外支持

• 批准号: 10024654
• 金额: $ 12.72万
• 依托单位: VINEHEALTH DIGITAL LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10024654
• 关键词: Randomised; controlled; trial; Vinehealth; digital

When cancer patients describe their experiences, they say: "\[information\] wasn't explained to me...you have to seek it out yourself", "it felt like they'd give you just enough information to go away with and then move on to the next patient", and "I didn't know what to expect when I went home".99% of cancer care occurs in patients' homes. Patients only get information and advice from clinicians in short, infrequent appointments. Therefore, patients must learn for themselves how best to manage their health. But the information they need is spread out across many charities, websites and publications. Often, this information is inconsistent and confusing.[][0]Better information is also urgently needed by drug companies. Following recent regulatory changes, pharmaceutical companies must collect patient-reported information on safety and effectiveness of their cancer drugs. They are struggling to collect these data.[][1]Pharmaceutical companies, clinicians and charities understand this situation is unacceptable and worsens cancer outcomes but do not have the remit, resources or technical skills to collaborate effectively to improve it.As a small, experienced, credible and trusted technology company, Vinehealth meets the needs of patients and drug companies for better information; already leading this via partnerships across the fragmented cancer care ecosystem. Vinehealth's digital tools combine behavioural science and AI to improve cancer patient QoL, and collect patient-reported outcome (PRO) data that drug companies need.The platform is co-developed with patients, leading UK oncologists, all major UK cancer charities, and the most significant pharmaceutical companies.Vinehealth includes a patient-facing mobile app that delivers personalised information and support to enable cancer patients to better self-manage their medications, side-effects, symptoms and lifestyles, seamlessly integrating with smartphones and wearables. Patients can regularly enter PRO data to drive clinical research, inform clinical service re-design and provide pharma with crucial PRO data. PRO data can increase cancer survival up to 20%.Feasibility of the tool has been confirmed in UK's leading cancer centre (Royal Marsden). For commercial success, we must now finalise Vinehealth technical development and deliver a large randomised controlled trial over four NHS Trusts, generating robust evidence for Vinehealth's clinical and cost effectiveness in improving patient self-management and data collection.Technical work to prepare for the trial includes ensuring Vinehealth meets the NHS sites' data governance and interoperability requirements and further developing the platform for more personalised psychological support and broader PRO measures.[0]: https://paperpile.com/c/H8DKSw/hrbH[1]: https://paperpile.com/c/H8DKSw/HQom

当癌症患者描述他们的经历时，他们说：“没有向我解释[信息]。你必须自己去寻找它”，“感觉他们会给你足够的信息，让你离开，然后转移到下一个病人”，“我不知道当我回家的时候会发生什么”。99%的癌症护理发生在病人家里。患者只能从临床医生那里得到简短、不频繁的信息和建议。因此，患者必须自己学习如何最好地管理自己的健康。但是他们需要的信息分散在许多慈善机构、网站和出版物上。通常，这些信息是不一致和混乱的。[][0]制药公司也迫切需要更好的信息。根据最近的监管变化，制药公司必须收集患者报告的有关其抗癌药物安全性和有效性的信息。他们正在努力收集这些数据。[][1]制药公司、临床医生和慈善机构都明白这种情况是不可接受的，会影响癌症的结果，但却没有足够的职权、资源或技术能力来有效地合作改善这种情况。作为一家经验丰富、可信和值得信赖的小型技术公司，Vinehealth满足了患者和制药公司对更好信息的需求;已经通过在分散的癌症护理生态系统中的合作伙伴关系引领了这一需求。Vinehealth的数字化工具联合收割机结合了行为科学和人工智能，以改善癌症患者的生活质量，并收集制药公司需要的患者报告结果（PRO）数据。该平台与患者，英国领先的肿瘤学家，所有主要的英国癌症慈善机构，Vinehealth包括一个面向患者的移动的应用程序，提供个性化的信息和支持，使癌症患者能够更好地自我治疗，管理他们的药物、副作用、症状和生活方式，与智能手机和可穿戴设备无缝集成。患者可以定期输入PRO数据来推动临床研究，通知临床服务重新设计，并为制药公司提供关键的PRO数据。PRO数据可以将癌症存活率提高20%。该工具的可行性已在英国领先的癌症中心（皇家马斯登）得到证实。为了取得商业上的成功，我们现在必须完成Vinehealth的技术开发，并在四个NHS信托基金上进行大型随机对照试验，为Vinehealth在改善患者自我方面的临床和成本效益提供强有力的证据，为试验做准备的技术工作包括确保Vinehealth符合NHS网站的数据治理和互操作性要求，并进一步开发平台，心理支持和更广泛的PRO措施。[0]：https：//paperpile.com/c/H8DKSw/hrbH [1]：https://paperpile.com/c/H8DKSw/HQom