Patients Registry -Virtual Biorepository Core
Patients Registry -Virtual Biorepository Core
批准号:
10153705
负责人:
JOSEPH EDWARD WILLIS
金额:
$29.05万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-09-26 至 2023-04-30
关键词:
AdherenceBarrett EsophagusBioinformaticsBiometryBiostatistics CoreClinicClinicalClinical DataComprehensive Cancer CenterComputational BiologyCore FacilityDataData AnalysesDatabase Management SystemsDatabasesDepartment chairDevelopmentEarly DiagnosisEnsureEsophageal AdenocarcinomaExperimental DesignsFacultyFormulationFoundationsGenetic DeterminismGenetic MarkersGoalsGrantGuidelinesHumanHuman ResourcesInformaticsInformation DisseminationInfrastructureInstitutesInstitutionLeadershipManuscriptsMedical centerMethodsMolecularNorth CarolinaOutcomePathologyPhysician ExecutivesPilot ProjectsPrevention therapyReproducibilityResearchResearch PersonnelResearch Project GrantsResourcesSaintsSecureSiteUniversitiesUniversity HospitalsWashingtonWorkWritingbiobankdata managementdata sharingdesignimprovedmedical schoolsoperationpatient registryprogramsrisk stratificationskillssuccesstissue resourcevirtual
中文摘要
摘要
我们BETRNet研究中心(RC)的主题是确定Barrett食道的遗传决定因素
(BE)和食管腺癌(EAC),使遗传标记能够引导早期发现,风险分层,
预防和治疗。BETRNet患者登记处-虚拟生物库(PRVB)核心将与所有
我们参与机构的RC调查员继续并改进有效的方法和设计
成功地使我们能够跨机构共享人类生物标本和临床数据,从而有效地实现
我们的项目目标是我们现有的BETRNet,并将使我们的新项目取得成功。我们交流
定期与我们的RC调查人员合作,以确保他们能够获得高质量的、经过临床注释的
为他们的研究问题提供生物标本。此外,核心还提供安全的基础设施和监督
来自BETRNet RC的所有生物样本、临床、人口学和分子数据的管理,工作中
与我们的调查人员和BETRNet管理核心密切合作。核心将确保遵守数据
遵循BETRNet协调中心和NCI概述的指导方针进行共享
BETRNet计划办公室,以便向其他BETRNet RCS提供生物标本和数据以供研究。
英文摘要
SUMMARY
The theme of our BETRNet Research Center (RC) is to identify genetic determinants of Barrett's esophagus
(BE) and esophageal adenocarcinoma (EAC) to enable genetic marker guided early detection, risk stratification,
prevention and therapy. The BETRNet Patients Registry-Virtual Biorepository (PRVB) Core will interact with all
RC investigators at our participating institutions to continue and improve the effective methods and designs that
successfully enabled us to share human biospecimens and clinical data across institutions to efficiently achieve
our project goals in our existing BETRNet and will enable success in our new projects. We communicate
regularly with our RC investigators to make sure they have access to high quality, clinically annotated
biospecimens for their research questions. In addition, the Core provides infrastructure and oversight for secure
management of all biospecimen, clinical, demographic and molecular data from the BETRNet RC, working
closely with our investigators and the BETRNet Administrative Core. The Core will ensure adherence to data
sharing in adherence with the guidelines as outlined from the BETRNet Coordinating Center and the NCI
BETRNet Program Office in order to provide biospecimens and data to other BETRNet RCs for research.
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专著(0)
科研奖励(0)
会议论文
Bioreagents & Resources Core
-
批准号:10713943
-
项目类别:
-
资助金额:$18.6万
-
财政年份:2023
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Pathology Core
-
批准号:10267197
-
项目类别:
-
资助金额:$5.29万
-
财政年份:2020
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Pathology Core
-
批准号:10478906
-
项目类别:
-
资助金额:$6.47万
-
财政年份:2020
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Pathology Core
-
批准号:10084626
-
项目类别:
-
资助金额:$5.5万
-
财政年份:2020
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Biospecimen/Pathology Core
-
批准号:10005928
-
项目类别:
-
资助金额:$10.02万
-
财政年份:2018
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Validation of Methylated Vimentin as a Diagnostic Test for Barrett's Esophagus
-
批准号:9923576
-
项目类别:
-
资助金额:$33.22万
-
财政年份:2016
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负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Core 1: Biospecimen Core
-
批准号:10227749
-
项目类别:
-
资助金额:$23.25万
-
财政年份:2011
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Project 2: Translational Significance of a Mutational Signature of African American Colon Cancers
-
批准号:10227753
-
项目类别:
-
资助金额:$23.25万
-
财政年份:2011
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Identification of Significant Race Associated Colon Cancer Drive Gene Mutations
-
批准号:8097073
-
项目类别:
-
资助金额:$27.32万
-
财政年份:2011
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Identification of Significant Race Associated Colon Cancer Drive Gene Mutations
-
批准号:8330850
-
项目类别:
-
资助金额:$10.24万
-
财政年份:2011
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Laser Capture Microdissection Instrument
-
批准号:6876424
-
项目类别:
-
资助金额:$19.95万
-
财政年份:2005
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Project 2: Translational Significance of a Mutational Signature of African American Colon Cancers
-
批准号:9753946
-
项目类别:
-
资助金额:$37.4万
-
财政年份:--
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Identifying Mutational Drivers of Late Stage Colon Cancer
-
批准号:8711345
-
项目类别:
-
资助金额:$30.14万
-
财政年份:--
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Identifying Mutational Drivers of Late Stage Colon Cancer
-
批准号:8567133
-
项目类别:
-
资助金额:$30.83万
-
财政年份:--
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Identifying Mutational Drivers of Late Stage Colon Cancer
-
批准号:8918467
-
项目类别:
-
资助金额:$30.62万
-
财政年份:--
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
Core 1: Biospecimen Core
-
批准号:9753943
-
项目类别:
-
资助金额:$15.05万
-
财政年份:--
-
负责人:JOSEPH EDWARD WILLIS
-
依托单位:
海外基金