Pathology Core

病理学核心

基本信息

  • 批准号:
    10267197
  • 负责人:
  • 金额:
    $ 5.29万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2020
  • 资助国家:
    美国
  • 起止时间:
    2020-09-21 至 2025-08-31
  • 项目状态:
    未结题

项目摘要

ABSTRACT – Path Core The Pathology Core will provide services to this proposal essential to the success of the projects. The Core will leverage existing technologies and infrastructure in Uganda and Tanzania as well as CWRU to provide reliable diagnoses of prospective project enrollees. The Pathology Core facilities include state of the art slide scanners which have been installed at the two African Pathology coordinating centers. The scanners are part of a large multi-institutional continent-wide program organized by the American Pathology of Clinical Pathology to improve surgical pathology diagnostic standards in Africa through a program of targeted infrastructure development. This program has enabled both teaching for faculty and residents in pathology diagnostics as well as facilitating pathology consultations across the globe. The slide scanning system and software are robust and user friendly. The program has been extremely successful and has been extensively implemented – linking multiple pathology departments in Africa to departments throughout the US and Europe. The design of the Core will facilitate rapid turnaround of pathology diagnoses through consensus. The two African center Pathology Leaders have extensive experience in the presentation of a host of non-cancerous lesions of the lung. This experience compliments that of Dr Willis, the Pathology Core Leader at CWRU, with his extensive experience in diagnostic oncology. The CWRU Pathology Core Center also has extensive experience in digital slide imaging management and translational research having extensive engagement with the CWRU Center for Computational Imaging & Personalized Diagnostics. Central to the mission of the core is standardization of diagnoses through teaching and cross center engagement. This will include cross visits by Drs Willis and Lukande. The core will also engage in important technology transfer of the technique of immunohistochemistry to both main sites in Africa. Immunohistochemistry is fundamental to modern diagnostic pathology and a pillar of diagnostic accuracy especially in oncology. Techniques to be introduced are designed to be used in low / middle resource centers and are flexible so that incremental additions to immunohistochemical panels can be performed with only minimal expenditures. The primary objective of the Core is to provide a resource that contributes significantly to the translational goals and endpoints of the individual projects, to facilitate cooperation between the three sites and to identify areas of potential further expansion of oncology–related translational research.
摘要-路径核心

项目成果

期刊论文数量(0)
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会议论文数量(0)
专利数量(0)

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JOSEPH EDWARD WILLIS其他文献

JOSEPH EDWARD WILLIS的其他文献

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{{ truncateString('JOSEPH EDWARD WILLIS', 18)}}的其他基金

Bioreagents & Resources Core
生物试剂
  • 批准号:
    10713943
  • 财政年份:
    2023
  • 资助金额:
    $ 5.29万
  • 项目类别:
Pathology Core
病理学核心
  • 批准号:
    10478906
  • 财政年份:
    2020
  • 资助金额:
    $ 5.29万
  • 项目类别:
Pathology Core
病理学核心
  • 批准号:
    10084626
  • 财政年份:
    2020
  • 资助金额:
    $ 5.29万
  • 项目类别:
Biospecimen/Pathology Core
生物样本/病理学核心
  • 批准号:
    10005928
  • 财政年份:
    2018
  • 资助金额:
    $ 5.29万
  • 项目类别:
Validation of Methylated Vimentin as a Diagnostic Test for Barrett's Esophagus
甲基化波形蛋白作为巴雷特食管诊断测试的验证
  • 批准号:
    9923576
  • 财政年份:
    2016
  • 资助金额:
    $ 5.29万
  • 项目类别:
Core 1: Biospecimen Core
核心 1:生物样本核心
  • 批准号:
    10227749
  • 财政年份:
    2011
  • 资助金额:
    $ 5.29万
  • 项目类别:
Project 2: Translational Significance of a Mutational Signature of African American Colon Cancers
项目 2:非裔美国人结肠癌突变特征的转化意义
  • 批准号:
    10227753
  • 财政年份:
    2011
  • 资助金额:
    $ 5.29万
  • 项目类别:
Identification of Significant Race Associated Colon Cancer Drive Gene Mutations
显着种族相关结肠癌驱动基因突变的鉴定
  • 批准号:
    8097073
  • 财政年份:
    2011
  • 资助金额:
    $ 5.29万
  • 项目类别:
Patients Registry -Virtual Biorepository Core
患者登记处-虚拟生物样本库核心
  • 批准号:
    10153705
  • 财政年份:
    2011
  • 资助金额:
    $ 5.29万
  • 项目类别:
Identification of Significant Race Associated Colon Cancer Drive Gene Mutations
显着种族相关结肠癌驱动基因突变的鉴定
  • 批准号:
    8330850
  • 财政年份:
    2011
  • 资助金额:
    $ 5.29万
  • 项目类别:

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