Development of Brief Interventions for Alcohol, Marijuana, and Sleep Problems in Young Adults

针对年轻人酒精、大麻和睡眠问题的简短干预措施的开发

• 批准号: 10155376
• 负责人: MARY E. LARIMER
• 金额: $ 14.63万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-15 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10155376
• 关键词: Abstinence; Accidental Injury; Accidents; Achievement; Address; Adolescent; Alcohol consumption; Alcoholic beverage heavy drinker; Alcohols; Automobile Driving; Behavior Therapy; Behavioral; Brief Alcohol Screening and Intervention for College Students; Cause of Death; Cessation of life; Cognitive Therapy; Comorbid Insomnia; Data; Decision Making; Depression and Suicide; Development; Distress; Drowsiness; Elderly; Event; Fatigue; Feedback; Homicide; Impaired cognition; Impairment; Inadequate Sleep Hygiene; Individual; Intervention; Link; Maintenance; Marijuana; Measures; Mental Health; Modeling; Motivation; Participant; Pattern; Performance; Periodicity; Physiological; Population; Prevalence; Prevention; Prevention program; Process; Public Health; REM Sleep; Randomized; Relapse; Reporting; Research; Risk; Risk Factors; Sample Size; Schedule; Schools; Sexual Development; Sleep; Sleep Disorders; Sleep disturbances; Sleeplessness; Stress; Students; Suicide; Surveys; Technology; Testing; Unsafe Sex; Work; actigraphy; addiction; alcohol comorbidity; alcohol consequences; alcohol effect; alcohol misuse; alcohol prevention; alcohol risk; alcohol use disorder; automobile accident; binge drinking; brief alcohol intervention; brief motivational intervention; cohesion; college; comorbidity; contextual factors; cost; design; diaries; drinking; experience; feasibility testing; follow-up; high risk; high risk drinking; improved; intervention effect; marijuana prevention; marijuana use; marijuana use disorder; obesity risk; poor sleep; post intervention; reduced alcohol use; secondary outcome; skills; sleep difficulty; sleep health; sleep onset; sleep quality; sleep quantity; social; success; therapy development; young adult; young adult alcohol use

PROJECT SUMMARY/ABSTRACT This application is designed to develop an integrated intervention to reduce alcohol and MJ use and consequences and improve sleep among young adults (YA) with comorbid heavy episodic drinking (HED), MJ use, and sleep impairment. HED in YA is an important public health problem, with consequences including accidental injury and death, academic or work problems, unsafe and unwanted sex, and development of alcohol use disorders. Many YA with HED also use MJ, often simultaneously, and experience increased harm as a result. Sleep impairment is common and problematic among YA, identified as the 3rd leading barrier to academic success for students and an important risk factor for mental health problems and suicide in YA. More than 60% of YA report frequent daytime fatigue, 27% extreme distress related to sleep problems, and more than 1 in 4 are at high risk for a sleep disorder. Alcohol use has been linked to impaired sleep in adolescent, YA, college, and older adult populations, with bidirectional causal links between alcohol use and impaired sleep, including negative physiological effects of alcohol on the sleep cycle (e.g., suppression of REM sleep), use of alcohol to promote sleep onset which can both increase alcohol use and resultant sleep impairment, and poor sleep hygiene including delayed and variable sleep-wake timing associated with cyclical patterns of alcohol use during evening and/or weekend social events. Comorbidity of HED and sleep impairment is associated with increased consequences of alcohol use, and exacerbates risk of accidents (including automobile accidents), impaired decision-making, and work and academic difficulties. Similar bidirectional relations exist with MJ use and sleep. Despite risks and consequences, alcohol and MJ prevention programs rarely target sleep directly, and the majority of YA interventions for sleep either focus on sleep hygiene broadly in the absence of specific strategies shown to improve sleep or reduce alcohol or MJ use, or have been relatively intensive interventions with insufficient sample size to truly evaluate impacts on sleep or related comorbid alcohol or MJ use. The current study addresses these gaps through developing and evaluating feasibility and preliminary efficacy of a brief, integrated intervention combining efficacious brief motivational feedback and skills for reducing HED and MJ use and consequences (BASICS) with Brief Behavioral Therapy for Insomnia (SLEEP) shown to improve sleep in other populations. Feasibility and efficacy will be evaluated over a 3-month period, using surveys and daily diaries to assess alcohol, MJ, and sleep at post-intervention and 3- months. Specific aims are: 1) Assess feasibility, acceptability, and preliminary efficacy BASICS + SLEEP in reducing alcohol use and consequences, improving sleep, and weakening daily and lagged (next day) relationships between alcohol and MJ use and sleep impairment; 2 Use diary data to explore daily and lagged relationships between alcohol use, MJ, sleep impairment, and unique YA contextual factor to further inform prevention of comorbid alcohol use, MJ, and sleep impairment.

项目总结/摘要 该应用程序旨在开发一种综合干预措施，以减少酒精和MJ的使用， 结果和改善睡眠的年轻人（YA）与共病重度发作性饮酒（HED），MJ 使用和睡眠障碍。也门的HED是一个重要的公共卫生问题，其后果包括 意外伤害和死亡，学业或工作问题，不安全和不想要的性行为，以及 酒精使用障碍许多患有HED的YA也经常同时使用MJ，并且会增加伤害 结果是。睡眠障碍在青少年中很常见，也是一个问题，被认为是第三大障碍， 学术成功的学生和一个重要的危险因素，心理健康问题和自杀的YA。更 超过60%的YA报告经常白天疲劳，27%的极端痛苦与睡眠问题有关，等等。 超过四分之一的人有睡眠障碍的高风险。饮酒与青少年睡眠受损有关， 青年、大学生和老年人人群，酒精使用和受损之间存在双向因果关系。 睡眠，包括酒精对睡眠周期的负面生理影响（例如，抑制REM睡眠）， 使用酒精来促进睡眠，这既可以增加酒精的使用，也可以导致睡眠障碍， 以及不良的睡眠卫生，包括与睡眠的周期性模式相关的延迟和可变的睡眠-觉醒定时， 在晚上和/或周末社交活动中饮酒。HED和睡眠障碍的合并症是 与饮酒后果增加相关，并加剧事故风险（包括 汽车事故），决策能力受损，以及工作和学业困难。相似双向 MJ使用与睡眠之间存在相关性。尽管有风险和后果，酒精和MJ预防计划 很少直接针对睡眠，大多数YA睡眠干预措施要么广泛关注睡眠卫生， 在缺乏改善睡眠或减少酒精或MJ使用的具体策略的情况下，或者已经 相对密集的干预措施，样本量不足，无法真正评估对睡眠或相关疾病的影响。 共病酒精或MJ使用。目前的研究通过开发和评估这些差距， 一个简短的，综合干预结合有效的简短动机的可行性和初步疗效 反馈和技能，以减少HED和MJ的使用和后果（BASICS）与简短的行为疗法 在其他人群中，INSIDE（睡眠）可以改善睡眠。将评估可行性和有效性 在3个月的时间内，使用调查和每日日记评估干预后的酒精、MJ和睡眠 三个月。具体目标是：1）评估可行性，可接受性和初步疗效BASICS + 睡眠在减少酒精的使用和后果，改善睡眠，并削弱每天和落后（下 日）之间的关系，酒精和MJ使用和睡眠障碍; 2使用日记数据，以探讨每日和 酒精使用、MJ、睡眠障碍和独特YA背景因素之间的滞后关系， 告知预防合并酒精使用、MJ和睡眠障碍。