Core B (Metabolomics Component)

核心 B（代谢组学成分）

• 批准号: 10153759
• 负责人: Arun Sreekumar
• 金额: $ 15.85万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10153759
• 关键词: Acyl Coenzyme A; Address; Amino Acids; Amino Sugars; Analytical Chemistry; Assessment tool; Basic Science; Bile Acids; Biochemical; Biochemical Pathway; Bioinformatics; Biological; Biological Assay; Biological Markers; Biometry; Cancer Biology; Carbon; Carnitine; Cell Line; Citric Acid Cycle; Clinical Research; Collaborations; Complement; Coupled; Data; Data Analyses; Data Set; Development; Discipline; Disease; Fatty Acids; Generations; Genetically Engineered Mouse; Glycolysis; Hexosamines; Individual; Infrastructure; Kinetics; Lead; Lipids; Mass Spectrum Analysis; Measurement; Measures; Mediator of activation protein; Metabolic; Metabolic Pathway; Metabolism; Methods; Nitrogen; Nuclear Receptors; Nucleotides; Pathway interactions; Pentosephosphate Pathway; Physiological; Proteins; Proteomics; Quality Control; Research Personnel; Specimen; Steroids; System; Technology; Tissue Extracts; Tissues; Translational Research; Vitamins; base; data analysis pipeline; detection method; innovation; mass spectrometer; metabolic phenotype; metabolomics; programs; research study; small molecule; statistics; sugar; therapeutic target; tool; transcriptomics

Core B (Metabolomics Component) -­ Project Summary    The metabolomics core will support this Program Project application by providing infrastructure, expertise and  support in metabolomics to investigators of the Program Project. The core will provide expertise in measurement  of  steady  state  levels  of  metabolites  and  their  flux  in  cell  lines  and  in  tissue  extracts  isolated  from  a  variety  of  genetically  engineered  mouse  models.  The  metabolomics  core  will  also  provide  assistance  with  downstream  data  analysis  and  interpretation  in  the  context  of  pathways,  as  well  as  support  the  development  and  implementation of innovative methods to integrate OMICs-­based datasets.

核心B（代谢组学成分）——项目总结