Bioprogramming the behaviour of nanoparticles in live cells by nanoscopy

通过纳米显微镜对活细胞中纳米颗粒的行为进行生物编程

• 批准号: DP210101792
• 负责人: Dr Francesca Cavalieri
• 金额: $ 28.27万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-04-23 至 2024-04-22
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210101792
• 关键词: Bioprogramming; behaviour; nanoparticles; live; cells

The project aims to develop safer materials that are sustainably sourced from sweet corn, and investigate using advanced imaging technologies, how these materials are processed in biological systems, including human and plant cells. This project expects to generate new knowledge in the optimal design of materials that can be used safely and effectively in biological applications in medicine and in agriculture. Expected outcomes of this multidisciplinary project include a library of highly biocompatible nanomaterials and expanded knowledge on imaging technologies and structure-function relationship of nanomaterials in biological cells. This should provide significant benefits, such as improved crop yields and safer transfection agents.

该项目旨在开发可持续地从甜玉米中获取的更安全的材料，并利用先进的成像技术研究这些材料如何在生物系统（包括人类和植物细胞）中加工。该项目期望在材料优化设计方面产生新的知识，这些材料可以安全有效地用于医学和农业的生物应用。这个多学科项目的预期成果包括建立一个高度生物相容性纳米材料库，以及扩展有关生物细胞中纳米材料的成像技术和结构功能关系的知识。这应该会带来显着的好处，例如提高作物产量和更安全的转染剂。