Florida Development in Early Childhood: Adversity and Drug Exposure (FL-DECADE) Study

项目摘要 在这项行政补充申请中，我们建议扩大我们的原始目的， 佛罗里达儿童早期发展：逆境和药物暴露（FL-DECADE）研究 （R34 DA 050299）完成与2019年新型冠状病毒相关的NIDA研究目标 （2019-nCoV，也称为COVID-19）。作为健康大脑和儿童第一阶段的一部分， 根据《六溴环十二烷发展研究》，本补编的拟议活动将提供额外的 关于孕妇和儿童长期队列研究可行性的信息 (HBCD第二阶段）。COVID-19肯定会在计划入学期间影响家庭 因此，从本行政管理报告中提出的活动中获得的知识 补充对于II期队列的早期成功至关重要。通过这一行政 补充，我们将获得一个广泛的了解压力和焦虑所面临的怀孕， 养育妇女在佛罗里达，以及他们的日常生活和产前护理如何改变， 流行病我们将评估使用非常大的临床数据研究网络的可行性， 确定COVID-19阳性的孕妇，以便确定目标 第二阶段招募的人群。最后，我们还将测试使用创新 从家里远程收集数据的方法，这对开发一个长期的 队列研究

PROJECT SUMMARY In this administrative supplement application, we propose to expand the original aims of our Florida Development in Early Childhood: Adversity and Drug Exposure (FL-DECADE) Study (R34DA050299) to accomplish NIDA research objectives related to the 2019 Novel Coronavirus (2019-nCoV, also known as COVID-19). As part of Phase I of the Healthy Brain and Child Development (HBCD) Study, the proposed activities of this supplement will provide additional information related to the feasibility of a long-term cohort study of pregnant women and children (HBCD Phase II). COVID-19 will assuredly impact families through the planned enrollment period of Phase II, thus the knowledge gained from the activities proposed in this administrative supplement are critical to the early success of the Phase II cohort. Through this administrative supplement, we will gain a broad understanding of stress and anxiety faced by pregnant and parenting women in Florida, and how their daily lives and prenatal care has changed during the pandemic. We will assess the feasibility of using a very large clinical data research network to identify pregnant women who are COVID-19 positive in the event it is decided to target this population for recruitment in Phase II. Finally, we will also test the feasibility of using innovative ways to remotely collect data from the home, which will be valuable in developing a long-term cohort study.