Center for Point-of-Care Technologies Research for Sexually Transmitted Diseases

性传播疾病护理点技术研究中心

• 批准号: 10159902
• 负责人: Yukari C Manabe
• 金额: $ 151.53万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10159902
• 关键词: Address; Algorithms; Anxiety; Back; Behavioral; Biological Assay; Centers for Disease Control and Prevention (U.S.); Chlamydia; Clinical; Clinical assessments; Communicable Diseases; Congenital Syphilis; Counseling; Country; Data; Development; Diagnosis; Diagnostic; Direct Costs; Disease; Education; Emerging Technologies; Engineering; Ensure; Epidemic; Facilities and Administrative Costs; Funding; Goals; Gonorrhea; HIV; Healthcare; Healthcare Systems; Home; Income; Individual; Infection; Lead; Medical Device; Mental Depression; Modeling; Needs Assessment; Newborn Infant; Patients; Personal Satisfaction; Point of Care Technology; Prevention; Privacy; Public Health; Reporting; Research; Resources; Rest; Sampling; Scientist; Self Care; Sexual Health; Sexually Transmitted Diseases; Structure; Syphilis; System; Technology; Testing; Training; Translations; United States; Universities; Validation; Woman; Work; World Health Organization; accurate diagnosis; behavior change; clinical translation; commercialization; design; health disparity; health inequalities; improved; indicated prevention; member; new technology; point of care; point of care testing; prevent; prototype; rapid diagnosis; self testing; social stigma; success; targeted treatment; technological innovation; transmission process

Project Summary The long-term goals of our center include addressing the epidemics of STDs/HIV in the U.S. and in resource-poor settings by development and better use of Point-of-Care (POC) tests, so as to address health inequity and improve the sexual health of individuals. Our specific aims are: 1. To develop a “Center of Excellence for the Development and Testing of Point of Care Tests (POCT) for Sexually Transmitted Diseases (STDs)” with cores that can: drive the development and application of point-of-care technologies via collaborative efforts that merge scientific and technological capabilities with clinical need and training of developers, as well as end users of POCT. 2. To use clinical drivers of technology progression for developing and expanding existing POC STD technologies, by providing assistance and feed back in an iterative fashion to developers in a “go-no go” manner, such that we insure that deliverables for each project are met. 3. To implement functioning core components that work smoothly together in a collaborative fashion and with other members of the Point-of-Care Technologies Research Network (POCTRN), which can work with our administrative component to implement a smooth transition along a pipeline from developmental prototype assays through early in- house, clinical translation and validation testing, In this coordinated manner, we can assist with the logical development of POC assays, which prove to have qualifications of sufficient scientific merit and can progress towards eventual FDA submission and commercialization. These goals and aims will be accomplished by an effective administrative component, ascertaining needs of users of POC, training of scientists, funding scientists and engineers for development of prototype and mature POC technologies, and pilot testing and implementation of POC tests in diverse clinical settings, which will lead to the commercialization and use of POC tests for diagnosing STDs in order to improve the sexual health of individuals in the United States and the rest of the world.

项目摘要 我们中心的长期目标包括解决美国性病/艾滋病毒的发作 以及通过开发和更好地利用即可（POC）测试的资源贫乏的设置，因此 以解决健康不平等并改善个人的性健康。我们的具体目标 为：1。为开发和测试护理的发展卓越中心 对性传播疾病（STD）的测试（POCT），可以： 通过合并的协作努力开发和应用即时的护理技术 具有临床需求和开发人员培训的科学和技术能力 作为POCT的最终用户。 2。使用技术进步的临床驱动力进行开发和 通过提供协助和反馈来扩展现有的POC性病技术 对开发人员的迭代方式以“不行”的方式，以便我们向可交付成果保证 每个项目都满足。 3。实现功能顺利合理的功能核心组件 以合作的方式以及护理技术研究的其他成员 网络（POCTRN），可以与我们的管理组件一起使用 沿管道顺利过渡，从开发原型测定到早期 房屋，临床翻译和验证测试，以这种协调的方式，我们可以协助 随着POC评估的逻辑发展，这证明具有足够的资格 科学功绩，可以朝着事件FDA提交和商业化迈进。 这些目标和目标将通过有效的行政组成部分来实现 确定POC用户的需求，培训科学家，资助科学家和工程师的需求 开发原型和成熟的POC技术，以及试点测试和实施 潜水员临床环境中的POC测试，这将导致商业化和使用 POC测试诊断性病，以改善联合个人的性健康 国家和世界其他地方。