Admin Core

管理核心

• 批准号: 10159903
• 负责人: CHARLOTTE Ann GAYDOS
• 金额: $ 34.65万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10159903
• 关键词: Address; Biological Assay; Biomedical Engineering; Clinical; Collaborations; Communication; Communities; Complex; Conflict (Psychology); Consensus; Databases; Development; Diagnostic; Discipline; Engineering; Ensure; Epidemic; Evaluation; Fostering; Funding; Goals; HIV; Human Resources; Individual; Industry; Institutes; Lead; Leadership; Maintenance; National Institute of Biomedical Imaging and Bioengineering; Nature; Performance; Point of Care Technology; Procedures; Progress Reports; Publications; Research; Research Personnel; Resources; Role; Science; Scientist; Services; Sexual Health; Sexually Transmitted Diseases; Structure; System; Technology; Testing; Training; United States National Institutes of Health; Update; Validation; Work; clinical translation; commercialization; design; health inequalities; improved; innovation; low and middle-income countries; meetings; member; multidisciplinary; outreach; point of care; point of care testing; prototype; support network; website development

Project Summary Administrative Core The Administrative Core, through the development and implementation of strategic integrated management systems, will work to support the Center of Excellence for the Development and Testing of Point-of-Care Tests (POCT) for Sexually Transmitted Diseases (STDs). We will lead, support, and assist our Cores to integrate and build multidisciplinary partnerships; to ensure outreach and communications to guarantee the inclusion of diverse expertise investigators, industry scientists, and engineers; to evaluate performance and guide performance improvement; and to cultivate service excellence in order to reach our Center's overall goals and specific aims, as well as the goals of the POC Technologies Research Network. The goals of our Administrative Core include addressing the epidemics of STDs/HIV in the U.S. and in low and middle income countries by development and better use of Point-of-Care (POC) tests, to address health inequity and improve sexual health. 1. We will support the Center of Excellence and all the individual Cores by assisting them for the development and verification of POC technologies via collaborative efforts that merge scientific and technological capabilities with clinical need and training of developers, as well as end users of POCT. 2. We will support the Cores as they use clinical drivers of technology progression for developing new and expanding existing POC Tests, by providing assistance insure that milestones for each project are met. 3. We will help to implement functioning core components that work smoothly together in a collaborative fashion and with other members of the Point-of-Care Technologies Research Network (POCTRN). 4. Our Administrative Core will implement a smooth transition along a pipeline from developmental of prototype assays through early in-house, clinical translation and validation testing. 5. Our operational administration will assist Cores to ascertain needs of end users of POC, train scientists, fund scientists and biomedical engineers for development of prototype and mature POC technologies, as well as pilot test and validate POC tests in diverse clinical settings. In this coordinated manner, we can assist with the logical development of POC assays, which will have sufficient scientific merit to progress to FDA submission and ultimate commercialization.

项目摘要 行政核心，通过制定和实施战略 综合管理系统，将致力于支持卓越中心， 性传播疾病即时检测（POCT）的开发和测试 疾病（性病）。我们将领导、支持和协助我们的核心团队整合和构建 多学科伙伴关系;确保外联和沟通， 包括各种专业知识的调查人员，行业科学家和工程师;评估 并指导绩效改进;并培养卓越的服务， 实现中心的总体目标和具体目标，以及POC的目标 技术研究网络。我们的行政核心的目标包括解决 美国和中低收入国家的性病/艾滋病流行情况， 更好地使用即时检验，以解决健康不平等问题，改善性健康。 1.我们将支持卓越中心和所有个人核心， 通过将科学和技术相结合的合作努力，开发和验证POC技术 临床需求和开发人员培训的技术能力，以及 POCT的使用者2.我们将支持核心，因为他们使用技术的临床驱动程序 通过提供帮助，开发新的和扩展现有的POC测试， 确保达到每个项目里程碑。3.我们将帮助实施功能核心 组件以协作方式顺利地协同工作，并与 护理点技术研究网络（POCTRN）。4.我们的行政核心将 实现从原型测定开发到沿着流水线的平稳过渡 通过早期的内部、临床翻译和验证测试。5.我们的运营 行政部门将协助核心确定POC最终用户的需求，培训科学家， 科学家和生物医学工程师开发原型和成熟的POC 技术，以及试点测试和验证POC测试在不同的临床环境。在这 通过协调一致的方式，我们可以协助POC检测的逻辑开发， 有足够的科学价值来推进FDA提交并最终商业化。