Center for Point-of-Care Technologies Research for Sexually Transmitted Diseases

我们中心的长期目标包括通过发展和更好地使用即时检测（POC）来解决美国和资源贫乏地区的性传播疾病和艾滋病毒的流行，从而解决健康不平等问题，改善个人的性健康。我们的具体目标是：1)提供一个中心管理结构，以确保这个庞大、复杂的中心及时实现其目标。2)进行临床医生、最终用户和其他相关利益相关者的综合临床需求评估和健康影响评估，期望通过将这些信息传播给技术开发社区，推动和告知POC测试设计、开发和利用领域。3)与物理和生物化学科学家，计算科学家和系统工程师合作，a)原型开发项目的探索性技术，b)更成熟poct的测试，以确保从概念阶段到临床测试阶段的分析沿着管道的逻辑进展。4)在临床情况和资源贫乏的国家测试成熟的POC检测方法，以加强在急诊科、家庭检测等环境中使用POC检测方法，并促进临床接受和使用此类检测方法，从而改善健康状况，特别是那些经历健康差异和不公平现象的人的健康。5)以迭代的方式为不同职业水平的技术开发人员提供临床和流程问题以及与POC设备开发相关需求的培训，并为资源贫乏地区的科学家提供培训，并向相关利益相关者提供关于POC技术开发和潜在影响的教育。这些目标和目标将通过一个有效的管理组件,确定POC的用户的需求,训练的科学家,资助的科学家和工程师为原型的发展和成熟POC技术和试验测试和实施POC测试在不同临床设置,这将导致POC的商业化和使用测试诊断性病为了提高个人的性健康在美国和世界其他国家。

The long-term goals of our center include addressing the epidemics of STDs and HIV in the U.S. and in resource-poor settings by development and better use of Point-of-Care (POC) tests, so as to address health inequity and improve the sexual health of individuals Our specific aims are 1) Provide a Center administrative structure to ensure that the large, complex Center achieves its goals in a timely manner.2) Conduct integrated clinical needs assessments and health impact assessments from clinicians, end-users, and other appropriate stakeholders, with the anticipation to advance and inform the field of POC testing design, development, and utilization by disseminating this information to the technology development community.3) Collaborate with physical and biochemical scientists, computational scientists, and systems engineers on a) exploratory technology for prototype development projects and b) for testing of more mature POCTs to insure a logical progression of assays along a pipeline from the concept stage to the clinical testing stage. 4) To test mature POC assays in clinical situations and in resource poor countries in order to enhance use of POC tests in settings such as emergency departments, home testing and to advance clinical acceptance and use of such tests and thus improve health especially for those experiencing health disparities and inequities.5) Provide training to technology developers across various career levels on clinical and process issues as well as needs related to the development of POC devices in an iterative fashion, as well as provide training for scientists in resource poor settins and education of relevant stakeholders on the development and potential impact of POC technologies. These goals and aims will be accomplished by an effective administrative component, ascertaining needs of users of POC, training of scientists, funding scientists and engineers for development of prototype and mature POC technologies, and pilot testing and implementation of POC tests in diverse clinical settings, which will lead to the commercialization and use of POC tests for diagnosing STDs in order to improve the sexual health of individuals in the United States and the rest of the world.