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中文摘要
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行政核心项目摘要/摘要 我们寻求推进NIAID的使命并通过实施 传染病基因组中心将利用各种尖端基因组 技术,包括基于实验室的方法、生物信息学过程和 防治传染病的计算分析。为了确保我们开展这项工作 高效,并为更广泛的研究社区带来最大利益,我们拥有 创建了一个负责管理该中心的管理核心。这个 管理核心拥有一支优秀的领导团队,具有悠久的 有效地协同工作。他们将把行业的管理实践应用于 支持推动高影响力研究的复杂、协作项目以及 为更广泛的社区创建和共享有价值的资源,包括基因组数据, 管道和分析工具。管理核心将管理我们中心的优先事项, 时间表和里程碑,并确保快速发布和传播公共数据 资源。为了支持我们工作的高度协作性质,管理核心将 还管理我们与合作研究人员、NIAID计划工作人员、 GCID指导委员会和其他由NIAID资助的中心,以确保密切协调 和合作。这将包括与科学家和技术专家在 BREADE和其他GCID开发新颖和创新的试点项目,并创造和 监督科学工作组以促进中心和 NIAID的任务。为了支持其他传染病研究人员使用方法, 我们产生的方法和资源,行政核心将监督外联工作 和教育活动,包括专门讲习班,接待来自 合作者,并支持本科生的传染病培训经验 来自历史上代表性不足的群体。通过建立和监测适当的 我们所有方面的绩效指标,并不断努力改进我们的 中心的流程和科学问题,行政核心将加速 努力了解和定义形成宿主-病原体和媒介-的因素- 病原体的相互作用,这些相互作用的功能后果和我们的能力 利用这一知识与传染病作斗争。
英文摘要
Administrative Core Project Summary/Abstract We seek to advance NIAID’s mission and address national needs by implementing a Genomic Center for Infectious Diseases that will utilize a variety of cutting-edge genomic technologies, including laboratory based methods, bioinformatics processes and computational analyses to combat infectious diseases. To ensure we carry out this work efficiently, and with maximum benefit for the wider research community, we have created an Administrative Core that will be responsible for managing the center. The Administrative Core features an outstanding leadership team with a long history of working effectively together. They will apply management practices from industry in support of complex, collaborative projects that advance high impact research as well as create and share valuable resources for the wider community, including genomic data, pipelines and analysis tools. The Admin Core will manage our Center’s priorities, timelines and milestones, and ensure rapid public data release and dissemination of resources. To support the highly collaborative nature of our work, the Admin Core will also manage our interactions with collaborating researchers, NIAID program staff, the GCID Steering Committee, and other NIAID funded Centers to ensure tight coordination and cooperation. This will include working with scientists and technology experts at Broad and other GCIDs to develop novel and innovative pilot projects and creating and overseeing Scientific Working Groups to advance the shared interests of the centers and NIAID’s mission. To support other infectious disease researchers’ use of methods, approaches and resources we generate, the Administrative Core will oversee outreach and educational activities, including specialized workshops, hosting extended visits from collaborators, and supporting infectious disease training experiences for undergraduates from historically underrepresented groups. By establishing and monitoring the proper metrics for all aspects of our performance, and constantly working to improve our Center’s processes and scientific questions, the Administrative Core will accelerate efforts to understand and define the factors that shape host-pathogen and vector- pathogen interactions, the functional consequences of those interactions and our ability to harness this knowledge to fight infectious diseases.
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Advancing Genomic Technologies to Combat Infectious Disease: Mapping Dynamics within Single Cells, Individual Hosts, and Global Populations
  • 批准号:
    10641432
  • 项目类别:
  • 资助金额:
    $138.47万
  • 财政年份:
    2022
  • 负责人:
    Bruce W. BIRREN
  • 依托单位:
The 200 mammals project: sequencing genomes by a novel cost-effective method, yielding a high resolution annotation of the human genome
  • 批准号:
    10087672
  • 项目类别:
  • 资助金额:
    $40.24万
  • 财政年份:
    2020
  • 负责人:
    Bruce W. BIRREN
  • 依托单位:
The 200 mammals project: sequencing genomes by a novel cost-effective method, yielding a high resolution annotation of the human genome.
  • 批准号:
    9173645
  • 项目类别:
  • 资助金额:
    $83.67万
  • 财政年份:
    2016
  • 负责人:
    Bruce W. BIRREN
  • 依托单位:
Advancing Genomic Technologies to Combat Infectious Disease: Mapping Dynamics within Single Cells, Individual Hosts, and Global Populations
  • 批准号:
    10610394
  • 项目类别:
  • 资助金额:
    $440.0万
  • 财政年份:
    2014
  • 负责人:
    Bruce W. BIRREN
  • 依托单位:
海外基金