Washington University Clinical Research Site for the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT)- RFA-NS-17-024

该项目将继续华盛顿大学NeuroNEXT网站为神经科学临床试验卓越网络（NeuroNEXT网站）计划做出贡献。该项目的总体目标将有助于成功确定并完成2期临床试验，这将加快神经系统疾病的概念转化为临床实践。该项目将通过支持关键领导人员，支持神经临床研究单位（NCRU）和WUSTL多中心临床试验绩效的行政基础设施，加强华盛顿大学圣路易斯分校（WUSTL）神经科学相关临床试验的基础设施。该拨款将提供关键领导，确保在WUSTL有效开展NeuroNEXT网络临床试验，资助现场PI和协调员，致力于确保及时准确地评估提议的概念，组织和支持现场协议团队，以及对NeuroNEXT试验的质量监督。该项目还通过资助优秀年轻研究者的项目，以及在理论和临床试验实践方面的指导和正式培训，为参与神经学临床研究的新兴研究者提供培训，从而丰富未来研究的研究者队伍。

This project will continue the Washington University NeuroNEXT site contributing to the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT sites) program. The overall goal of the program will contribute to the success in identifying and completing Phase 2 clinical trials that will speed translation of concepts to clinical practice for neurological conditions. The project will enhance the infrastructure for neuroscience related clinical trials at Washington University in St Louis (WUSTL) through supporting critical leadership personnel, support for the Neurological Clinical Research Unit (NCRU) and administrative infrastructure for multicenter clinical trials performance at WUSTL. The grant will provide key leadership assuring the efficient conduct of NeuroNEXT network clinical trials at WUSTL by funding a site PI and coordinator committed to assuring timely and accurate assessment of proposed concepts, organization and support of site protocol teams, and quality oversight for NeuroNEXT trials. The project also supports training for emerging investigators for participation in neurological clinical research through a program to support an outstanding younger investigator financially and through mentoring and formal training in theoretical and practical clinical trial practices, thus enriching the pool of investigators available for future investigations.