Washington University Clinical Research Site for the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT)- RFA-NS-17-024

华盛顿大学神经科学临床试验卓越网络 (NeuroNEXT) 临床研究网站 - RFA-NS-17-024

• 批准号: 10163925
• 负责人: DAVID B CLIFFORD
• 金额: $ 28.83万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10163925
• 关键词: Address; Adult; Affect; Agreement; Biological Markers; Childhood; Clinical; Clinical Research; Clinical Trials; Clinical Trials Design; Clinical Trials Network; Data; Development; Fostering; Funding; Future; Goals; Grant; Health; Human; Human Resources; Infrastructure; Institution; Institutional Review Boards; Investigation; Leadership; Link; Maintenance; Mentors; Mission; Monitor; Multi-Institutional Clinical Trial; National Institute of Neurological Disorders and Stroke; Neurologic; Neurologist; Neurology; Neurosciences; Neurosurgeon; Patients; Performance; Phase; Phase II Clinical Trials; Protocols documentation; Psychiatrist; Reaction Time; Records; Research; Research Design; Research Personnel; Research Support; Resources; Site; Specialist; Speech Therapist; Speed; Time; Training; Training Support; Translations; Universities; Washington; Work; career development; clinical practice; clinical research site; clinical translation; data submission; design; experience; improved; nervous system disorder; neuroimaging; neurological rehabilitation; phase 2 study; prevent; programs; recruit; success; support network; training opportunity

This project will continue the Washington University NeuroNEXT site contributing to the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT sites) program. The overall goal of the program will contribute to the success in identifying and completing Phase 2 clinical trials that will speed translation of concepts to clinical practice for neurological conditions. The project will enhance the infrastructure for neuroscience related clinical trials at Washington University in St Louis (WUSTL) through supporting critical leadership personnel, support for the Neurological Clinical Research Unit (NCRU) and administrative infrastructure for multicenter clinical trials performance at WUSTL. The grant will provide key leadership assuring the efficient conduct of NeuroNEXT network clinical trials at WUSTL by funding a site PI and coordinator committed to assuring timely and accurate assessment of proposed concepts, organization and support of site protocol teams, and quality oversight for NeuroNEXT trials. The project also supports training for emerging investigators for participation in neurological clinical research through a program to support an outstanding younger investigator financially and through mentoring and formal training in theoretical and practical clinical trial practices, thus enriching the pool of investigators available for future investigations.

该项目将继续华盛顿大学NeuroNEXT网站，为神经科学临床试验卓越网络(NeuroNEXT网站)计划做出贡献。该计划的总体目标将有助于成功识别和完成第二阶段临床试验，这将加快将概念转化为神经疾病的临床实践。该项目将通过支持关键领导人员、支持神经临床研究单位(NCRU)以及圣路易斯华盛顿大学多中心临床试验绩效的管理基础设施，来加强与神经科学相关的临床试验的基础设施。这笔赠款将提供关键的领导，通过为SITE PI和协调员提供资金，确保在WUSTL有效地进行NeuroNEXT网络临床试验，该协调员致力于确保对拟议概念进行及时和准确的评估，SITE方案团队的组织和支持，以及NeuroNEXT试验的质量监督。该项目还支持对新出现的研究人员进行参与神经学临床研究的培训，该计划旨在为一名杰出的年轻研究人员提供财政支持，并通过理论和临床试验实践方面的指导和正式培训，从而丰富可用于未来研究的研究人员队伍。