Nebraska Center for Nanomedicine

摘要 多学科的内布拉斯加州纳米医学中心（NCN），成立于2008年，与中心 生物医学研究卓越（COBRE）的资金，正在建立一个国家和国际公认的 卓越的纳米医学计划，结合了材料，制药和 创新研究驱动的生物科学。NCN已经完成了其最初的目标，并加强了 内布拉斯加州的生物医学研究能力，通过创建一个强大的研究战略连接的基础设施 课程和指导有才华的初级教师干部独立成功。在前9年， 资助，NCN资助的初级教师获得了超过1800万美元的新的研究资金，8个NCN 受训人员已获得终身教职和/或晋升，八名新的初级和高级教员具有与以下方面有关的专门知识： NCN被招募到药学院。我们的毕业生已被任命为编辑委员会， 在审查小组，并有无数的邀请，目前研讨会。这份NCN COBRE延续提案 详细介绍了我们的计划，以保持一个生物医学研究中心的国家突出和国际认可。 推动NCN实现这些目标的具体目标是：1）继续扩大现有的研究 通过支持合作的跨学科研究和初级教师的导师制来发挥优势; 2） 加强研究能力、创新和对NCN附属研究人员的资金支持; 3） 确保科学核心设施的可持续性，这对中心的持续发展至关重要， 服务于广大的研究群体。这些目标的实现将使NCN能够从阶段 III资助作为纳米医学卓越研究的自我维持中心，具有更高的能力， 通过个人和多名研究人员、全方案研究赠款寻求方案支助。 通过有效的纳米药物的开发和临床转化， NCN将最终为内布拉斯加人和社会的健康提供重大利益 逍遥法外

ABSTRACT The multidisciplinary Nebraska Center for Nanomedicine (NCN), established in 2008 with the Center for Biomedical Research Excellence (COBRE) funding, is building a nationally and internationally recognized program of excellence in nanomedicine that combines broad expertise in material, pharmaceutical and biological sciences driven by innovative research. NCN has completed its original objectives and enhanced Nebraska's biomedical research capacity by creating a strategically linked infrastructure of strong research programs and by mentoring a cadre of talented junior faculty to independent success. In the first 9 years of funding, the NCN-funded junior faculty members obtained over $18 million in new research funds, eight NCN trainees have been tenured and/or promoted, eight new junior and senior faculty with expertise relevant to NCN were recruited to the College of Pharmacy. Our graduates have been appointed to editorial boards, serve on review panels, and have countless invitations to present seminars. This NCN COBRE continuation proposal details our plan to maintain a biomedical research center of national prominence and international recognition. The specific aims that move the NCN toward these goals are: 1) continue to expand existing research strengths through the support of collaborative interdisciplinary research and mentorship of junior faculty; 2) strengthen research capabilities, innovation and funding support for investigators affiliated with the NCN; 3) assure sustainability of scientific core facilities that are essential for the continued growth of the Center and serve the research community at large. The realization of these aims will allow the NCN to emerge from Phase III funding as self-sustaining center of research excellence in nanomedicine, with an increased capacity to pursue programmatic support through individual and multi-investigator, program-wide research grants. Through the development and clinical translation of effective nanomedicines for diagnosis and therapy for human diseases, the NCN will ultimately provide significant benefits for the health of Nebraskans and society at large.