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Alliance NCORP Research Base

联盟NCORP研究基地

基本信息

批准号：
10172168
负责人：
Monica M Bertagnolli
金额：
$ 767.3万
依托单位：
ALLIANCE NCTN FOUNDATION
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-08-01 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10172168
关键词：
Academic Medical Centers Address Advocate Aging Area Attention Behavior Blood Cancer Burden Cancer Patient Cancer Research Project Caregivers Clinical Clinical Research Clinical Trials Collaborations Collection Committee Membership Communities Community Clinical Oncology Program Companions Data Data Reporting Databases Development Diagnosis Disease Education Elderly Functional disorder Funding Funding Opportunities Grant Health Human Incidence Intervention Intervention Studies Maintenance Malignant Neoplasms Manuscripts Mentors Mentorship Metastatic Neoplasm to the Bone Metastatic malignant neoplasm to brain Minority Mission Monitor Morbidity - disease rate National Cancer Institute National Clinical Trials Network Natural History Nausea and Vomiting Oncologist Oncology Outcome Outcome Assessment Outcomes Research Parents Patient Outcomes Assessments Patients Pharmacologic Substance Population Prevalence Prevention Publishing Quality of life Research Research Methodology Research Personnel Research Priority Risk Site Source Symptoms Technology Tissue Sample Toxic effect Training Translational Research Tumor Tissue United States Work base cancer care cancer clinical trial cancer health disparity cancer prevention cancer risk cancer therapy care delivery chemotherapy clinically relevant clinically significant curative treatments data sharing disparity reduction experience financial toxicity health disparity high risk improved innovation mortality multidisciplinary next generation novel older patient premalignant prevent programs reduce symptoms repository skeletal-related events survivorship treatment trial underserved minority

项目摘要

Alliance NCORP Research Base Project Summary/Abstract The Alliance for Clinical Trials in Oncology (Alliance), one of five National Clinical Trials Network groups, serves as the parent organization for the Alliance NCI Community Oncology Research Program (NCORP) Research Base (Alliance NCORP). The Alliance NCORP conducts interventional and observational clinical and translational research as well as database studies – all of which address important questions relevant to cancer prevention, symptom control, and cancer care delivery. In addition, the Alliance NCORP conducts clinically important quality of life studies that are embedded within cancer treatment trials. It places special emphasis on minority, underserved and older patients at risk for or diagnosed with cancer, and on building strong collegial relationships with NCORP Community sites and Minority/Underserved Community sites. The Alliance NCORP committee membership includes rich representation from both community-based and academic medical centers, as well as patient advocates, thus generating research results relevant to cancer patients across the United States. The Alliance NCORP also emphasizes mentorship and training of junior investigators. Over this past grant cycle, i.e., since August 2014, the Alliance NCORP has published 148 manuscripts and abstracts. This work has included practice-changing research in such areas as the prevention of chemotherapy-induced nausea and vomiting, the prevention of skeletal-related events from osseous metastases, the management of brain metastases, and the integration of patient-reported outcomes into cancer clinical trials. The Alliance NCORP conducts translational research that requires the collection of tumor tissue, premalignant tissue samples, blood, and other human biospecimens; and shares data and biospecimens for pooled analyses and other scientific collaborations. These biospecimens create an invaluable repository for understanding clinical observations from a mechanistic standpoint. The Alliance NCORP also collaborates broadly with other NCI-funded investigators and consortia, as well as with investigators supported through non-NCI sources. This practice-changing research and the scientific questions answered by the Alliance NCORP provide meaningful and innovative contributions to clinical and translational oncology, which can be conducted only within a publicly-funded research network.

联盟非营利组织研究基地