Alliance for Clinical Trials in Oncology Operations Center

肿瘤学临床试验联盟运营中心

• 批准号: 9132519
• 负责人: Monica M Bertagnolli
• 金额: $ 81.04万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-17 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9132519
• 关键词: Adoption; Adult; American College of Surgeons Oncology Group; Area; Biological; Biological Markers; Breast; Cancer Burden; Cancer Center; Cancer Control; Cancer Patient; Cancer Survivorship; Cancer and Leukemia Group B; Clinic; Clinical; Clinical Research; Clinical Treatment; Clinical Trials; Clinical Trials Cooperative Group; Clinical Trials Design; Collaborations; Communities; Consensus; Cooperative Group Program; Data; Discipline; Disease; Economically Deprived Population; Economics; Elderly; Enrollment; Equilibrium; Evaluation; Event; Funding; Genetic; Genitourinary system; Genotype; Goals; Health; Healthcare; Hematologic Neoplasms; Image; Industry; Institute of Medicine (U.S.); Investments; Leadership; Life; Link; Malignant Neoplasms; Malignant neoplasm of pancreas; Medical Device; Mission; Modality; Molecular; North Central Cancer Treatment Group; Outcome; Pathogenesis; Patient Care; Patients; Pharmacologic Substance; Population; Prevalence; Prevention; Prevention strategy; Prevention trial; Principal Investigator; Process; Refractory; Reporting; Research; Research Design; Research Infrastructure; Research Personnel; Resource Sharing; Resources; Scientist; Societies; Structure; System; Therapeutic; Time; Training; Translating; Translational Research; Treatment outcome; Underrepresented Minority; Underserved Population; United States National Academy of Sciences; Validation; Work; base; cancer therapy; clinical care; clinical practice; community setting; control trial; design; experience; falls; gastrointestinal; improved; individualized medicine; innovation; insight; malignant breast neoplasm; meetings; member; mortality; multidisciplinary; multimodality; named group; next generation; novel; novel strategies; oncology; operation; programs; psychosocial; respiratory; response; screening; sobriety; statistics; success; symptom management; translational clinical trial; treatment strategy; treatment trial; trial design; tumor

DESCRIPTION (provided by applicant): The Alliance is an experienced multi-institutional cancer clinical trials group that has been reorganized in response to the Institute of Medicine (lOM) consensus report and NCI directives for cooperative group reorganization. Alliance provides a comprehensive and highly efficient clinical trials infrastructure, access to experienced collaborators across all disciplines of oncology clinical trials research, and a diverse portfolio f trials for patients with breast, gastrointestinal, genitourinary, respiratory, central nervous systm, hematological malignancies, and selected rare tumors. Particular strengths of the Alliance include the long-standing tradition of collaborative research of the legacy members, including many who have participated in cooperative group research since its inception in 1955. The Mission of the Alliance for Clinical Trials in Oncology is to reduce the impact of cancer by: - Conducting high quality multidisciplinary cancer control, prevention, and treatment trials that engage a comprehensive research network; - Furthering our understanding of the biological basis of the cancer process and its treatment; from discovery, to validation, to clinical practice;- Providing a scientific and operational infrastructure for innovative clinical and translational research in the academic and community settings.

描述(由申请人提供)：该联盟是一个经验丰富的多机构癌症临床试验小组，已根据医学研究所(LOM)共识报告和NCI关于合作小组重组的指示进行了重组。联盟提供全面而高效的临床试验基础设施，获得经验丰富的 肿瘤学临床试验研究的所有学科的合作者，以及乳房、胃肠、泌尿生殖、呼吸系统、中枢神经系统、血液系统恶性肿瘤和选定的罕见肿瘤患者的各种试验组合。该联盟的特别优势包括传统成员合作研究的长期传统，其中包括自1955年成立以来参与合作小组研究的许多人。肿瘤学临床试验联盟的使命是通过以下方式减少癌症的影响：-进行高质量的多学科癌症控制、预防和治疗试验，利用全面的研究网络；-加深我们对癌症过程及其治疗的生物学基础的了解；-从发现、验证到临床实践；-为学术和社区中的创新临床和转化研究提供科学和操作基础设施。