Interactive contouring simulation (iContour) to improve outcomes of cancer patients treated with radiation therapy

项目摘要/摘要 放射治疗在癌症的治疗中起着核心作用。提供安全有效的辐射 关键在于识别辐射目标(肿瘤)和要避开的区域(正常组织)的能力。行为…的行为 定义辐射目标--称为轮廓--需要对解剖学有良好的理解， 放射学，最重要的是个别病人。现有的研究清楚地表明，糟糕的轮廓 导致毒性增加，生存率下降，这强调了轮廓交付的重要性 安全有效的放射治疗。 该项目建议创建并测试一种基于模拟的教育方法，以提高轮廓质量 在放射肿瘤学方面。该等高线模拟工具将使放射肿瘤学提供商能够 轮廓测试用例，并接收有关其轮廓准确性的快速反馈。我们将使用基于知识的 计划帮助提供关于现实生活中毒性风险和治愈机会的反馈，它们的轮廓是 用来治疗那个病人。使用迭代和参与式设计，我们将让利益相关者参与开发 全面的基于Web的交互式模拟工具(IConstraint)，以及更专注的移动应用程序 (iConstraint-移动)。成功的教育应用程序需要用户参与，因此需要增加用户 参与度我们将利用游戏化和社交媒体的组件。通过随机临床试验 将在真实的患者轮廓上测试这些不同模拟策略的效果。总体而言，这项研究试图 定义了如何改善真实世界轮廓的最佳模拟策略。 如果成功，这种基于模拟的教育方法可以改变轮廓教育，并发挥 在住院医师教育、继续医学教育和辐射委员会认证方面发挥核心作用 并可作为开发医学其他领域的模拟培训工具的模型。

PROJECT SUMMARY/ABSTRACT Radiation therapy plays a central role in the treatment of cancer. The delivery of safe and effective radiation hinges on the ability to identify the radiation target (tumor), and areas to avoid (normal tissues). The act of defining the radiation target – referred to as contouring – requires a sound understanding of anatomy, radiology, and most importantly the individual patient. Existing research clearly shows that poor contouring leads to increased toxicity, and decreased survival, which emphasizes the importance of contouring to deliver safe and effective radiation therapy. This project proposes to create and test a simulation-based educational approach to improving contour quality in radiation oncology. This contouring simulation tool will allow radiation oncology providers the ability to contour test cases and receive rapid feedback on the accuracy of their contours. We will use knowledge-based planning to help provide feedback on the real life risks of toxicity and chances of cure had their contours been used to treat that patient. Using iterative and participatory design we will engage stakeholders to develop a comprehensive interactive web-based simulation tool (iContour), as well as a more focused mobile application (iContour-mobile). Successful educational applications require user engagement, therefore to increase user engagement we will leverage components of gamification and social media. With a randomized clinical trial we will test the efficacy of these different simulation strategies on real patient contours. Overall, this study seeks to define the optimal simulation strategy of how to improve real-world contouring. If successful this simulation-based education approach could transform contouring education and play a central role in residency education, continuing medical education, and board certification for radiation oncology, and serve as a model for developing simulation training tools for other fields in medicine.