Special Projects: Analytical Track 3: Method Development/Validation

摘要：特殊项目轨道3(方法开发和验证) MDH实验室管理局高度重视开发和实施切割- 边缘技术和能力。这一庞大而多方面的提案的核心原则是 一个全面和综合的食品保护实验室中心，以应对粮食危机 网络(蕨类)，能够分析许多不同的食物，跨越各种威胁优先级。 因此，开发和验证新的测试方法是实现我们确保 安全的食品供应。通过这一轨道，MDH实验室管理局提议进行 初步的、短期的或探索性的调查，如弗恩所需的，侧重于 一种新方法和/或技术。该实验室将遵循食品和药物管理局(FDA)的规定 《FDA FVM化学方法验证》中描述的方法验证指南 计划“，以完成为期一年的单一实验室验证研究。环境学部 Sciences拥有所有的仪器，包括5个电感耦合等离子体质谱仪和3个LC-MS/MS质谱仪， 多位专家和经验丰富的科学家，并建立了执行这些任务的方法 学习。本合作协议的每一年的项目将根据弗恩的情况进行选择。 根据当地新出现的优先事项和机会，与 弗恩管理团队。

SUMMARY: SPECIAL PROJECT TRACK 3 (METHOD DEVELOPMENT AND VALIDATION) The MDH Laboratories Administration places a high priority on developing and implementing cutting- edge technologies and capabilities. The core tenet of this large and multifaceted proposal is to contribute a comprehensive and integrated food protection laboratory hub to the Food Emergency Response Network (FERN) that is capable of analyzing many different foods across a diversity of threat priorities. Developing and validating new testing methods is thus central to achieving our goal of ensuring a safe food supply. Through this track the MDH Laboratories Administration proposes to conduct preliminary, short-term, or exploratory investigations, as needed by FERN, that focus on the feasibility of a new method and/or technology. The Laboratory will follow the Food & Drug Administration’s (FDA) guidelines for method validation as described in “Validation of Chemical Methods for the FDA FVM Program” to complete a one-year, single-laboratory validation study. The Division of Environmental Sciences has all of the instrumentation, including 5 ICP-MS and 3 LC-MS/MS mass spectrometers, multiple expert and experienced scientists, and established methodologies in place to perform these studies. Projects for each of the five years of this cooperative agreement will be chosen based on FERN needs, and/or proposed based on emerging local priorities and opportunities, in consultation with the FERN management team.