Special Projects: Analytical Track 3: Method Development/Validation

摘要：特殊项目轨道3（方法开发和验证） MDH实验室管理局高度重视开发和实施切割- 边缘技术和能力。这一庞大而多方面的提案的核心宗旨是， 一个全面和综合的食品保护实验室中心，以应对食品紧急情况 该网络（FERN）能够分析各种威胁优先级的许多不同食物。 因此，开发和验证新的测试方法是实现我们确保 安全食品供应。通过这条轨道，MDH实验室管理局建议进行 初步的，短期的，或探索性的调查，根据需要的FERN，重点是可行性， 新的方法和/或技术。实验室将遵循美国食品药品监督管理局（FDA） 方法验证指南，如“FDA FVM化学方法验证”中所述 计划”完成为期一年的单实验室验证研究。环境司 科学拥有所有的仪器，包括5个ICP-MS和3个LC-MS/MS质谱仪， 多位专家和经验丰富的科学家，并建立了执行这些任务的方法 问题研究本合作协议五年中的每一年的项目将根据FERN进行选择 根据当地新出现的优先事项和机会，与 Fern管理团队。

SUMMARY: SPECIAL PROJECT TRACK 3 (METHOD DEVELOPMENT AND VALIDATION) The MDH Laboratories Administration places a high priority on developing and implementing cutting- edge technologies and capabilities. The core tenet of this large and multifaceted proposal is to contribute a comprehensive and integrated food protection laboratory hub to the Food Emergency Response Network (FERN) that is capable of analyzing many different foods across a diversity of threat priorities. Developing and validating new testing methods is thus central to achieving our goal of ensuring a safe food supply. Through this track the MDH Laboratories Administration proposes to conduct preliminary, short-term, or exploratory investigations, as needed by FERN, that focus on the feasibility of a new method and/or technology. The Laboratory will follow the Food & Drug Administration’s (FDA) guidelines for method validation as described in “Validation of Chemical Methods for the FDA FVM Program” to complete a one-year, single-laboratory validation study. The Division of Environmental Sciences has all of the instrumentation, including 5 ICP-MS and 3 LC-MS/MS mass spectrometers, multiple expert and experienced scientists, and established methodologies in place to perform these studies. Projects for each of the five years of this cooperative agreement will be chosen based on FERN needs, and/or proposed based on emerging local priorities and opportunities, in consultation with the FERN management team.