NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens

NARMS 加强零售食品样本抗生素耐药性监测的合作协议计划

• 批准号: 10477282
• 负责人: SINISA URBAN
• 金额: $ 17万
• 依托单位: MARYLAND STATE DEPARTMENT OF HEALTH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10477282
• 关键词: NARMS; Cooperative; Agreement; Program; Strengthen

PAR-20-124, NARMS Cooperative Agreement Program to Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens (U01) MD Department of Health, 2020 ABSTRACT Foodborne bacterial infections have contributed to morbidity and mortality world-wide. To track antimicrobial resistance in enteric bacteria isolated from retails meat products, National Antimicrobial Resistance Monitoring System (NARMS) was established to perform public health surveillance in the United States. The Maryland Department of Health (MDH) has been a partner with the NARMS program for numbers of years and has been successfully contributing to the data development used in the bacterial illness and antimicrobial resistance studies. At MDH, the project has been performed in collaboration between MDH epidemiologists and MDH laboratory scientists to assure the quality of the data. Retail meats including ground beef, ground turkey, pork, chicken and seafoods are purchased from stores across the State of Maryland and processed according to the protocols established by the NARMS program. The target organisms from the retail meats include Salmonella, E. coli and Enterococci and Campylobacter whereas Vibrio, Aeromonas, Enterococcus and lactose fermenting bacteria are isolated from seafood products. The isolate identification is confirmed with appropriate methods before submitted to the FDA. Isolates including E. coli, Campylobacter and Salmonella are subjected to whole genome sequencing and the data are submitted to the FDA. After all isolates are confirmed and frozen, they are shipped to the FDA for antibiotic susceptibility testing and further characterization.

PAR-20-124，NARMS合作协议方案， 加强零售食物样本的抗生素耐药性监测（U 01） MD卫生部，2020 摘要 食源性细菌感染导致了世界范围内的发病率和死亡率。跟踪 从零售肉制品中分离的肠道细菌的耐药性，国家 建立了抗菌药物耐药性监测系统（NARMS）， 美国的健康监测。马里兰州卫生部（MDH）一直是一个 多年来，我一直与NARMS计划合作，并成功地为 在细菌疾病和抗菌素耐药性研究中使用的数据开发。在 MDH，该项目已在MDH流行病学家和MDH之间合作进行 实验室科学家确保数据的质量。零售肉类，包括碎牛肉、碎牛肉 火鸡、猪肉、鸡肉和海鲜是从马里兰州各地的商店购买的， 根据NARMS程序建立的协议进行处理。目标生物体 来自零售肉类的沙门氏菌、E.大肠杆菌和肠球菌和弯曲杆菌， 从海产品中分离到弧菌、气单胞菌、肠球菌和乳糖发酵菌 产品.在提交给 FDA。分离株包括E.大肠杆菌，弯曲杆菌和沙门氏菌受到整个 基因组测序和数据提交给FDA。所有分离株确认后， 冷冻后，它们被运送到FDA进行抗生素敏感性测试， 特征化