Microbiology Whole Genome Sequencing

微生物学全基因组测序

• 批准号: 10174327
• 负责人: Lauren Turner
• 金额: $ 13.73万
• 依托单位: VA DIVISION/CONSOLIDATED LAB SRVS
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10174327
• 关键词: Microbiology; Whole; Genome; Sequencing

PAR-20-105 Laboratory Flexible Funding Model (LFFM) (U19) Microbiology Discipline Analytical Track 4: Whole-Genome Sequencing Virginia Division of Consolidated Laboratory Services Principal Investigator: Lauren Turner, PhD Project Summary The Division of Consolidated Laboratory Services (DCLS) is the public health laboratory for the Commonwealth of Virginia and offers a wide variety of laboratory testing services for state and federal agencies, local governments, and other states in support of public health, environmental protection, and emergency response. DCLS provides surveillance and emergency response testing of food samples for the Virginia Department of Agriculture and Consumer Services (VDACS) Food Safety Program by offering nearly comprehensive testing of food samples by microbiology, chemistry, and radiochemical methods. DCLS is a long-term participating partner in the FDA CFSAN GenomeTrakr program and proposes to further enhance the GenomeTrakr Network pathogen databases by generating and sharing genome sequences of more than 400 pathogen isolates from food, environmental, and animal sources during the budget period. The genomic information made available through the GenomeTrakr Network can identify food products potentially associated with an outbreak, assist with traceback of contaminated food ingredients, aid in compliance monitoring of facilities with previous pathogen contamination issues, and can improve the understanding of pathogen attributes associated with virulence and pathogenicity.

PAR-20-105实验室灵活资助模式（LFFM）（U19） 微生物学科 分析方向4：全基因组测序 统一实验室服务弗吉尼亚分部 主要研究者：Lauren Turner，PhD 项目摘要 综合实验室服务部（DCLS）是公共卫生实验室， 弗吉尼亚联邦，为州和联邦提供各种实验室检测服务 机构，地方政府和其他国家支持公共卫生，环境保护， 应急处置食物安全及食物安全局提供食物样本监察及紧急应变测试服务， 弗吉尼亚州农业和消费者服务部（VDACS）食品安全计划， 通过微生物学、化学和放射化学方法对食品样品进行近乎全面的检测。 DCLS是FDA CFSAN GenomeTrakr计划的长期参与合作伙伴，并建议 通过生成和共享基因组，进一步增强GenomeTrakr网络病原体数据库 来自食品，环境和动物来源的400多个病原体分离物的序列， 预算期间。通过GenomeTrakr网络提供的基因组信息可以识别 可能与疫情有关的食品，协助追溯受污染食品 成分，帮助对先前存在病原体污染问题的设施进行合规性监测，以及 可以提高对与毒力和致病性相关的病原体属性的理解。