MICROBIOLOGY (WHOLE GENOME SEQUENCING - TRACK 4)

项目概要： 该项目的主要目标是支持食品和药物管理局（FDA）通过执行全基因组 对从人类和/或动物食品中收集的细菌病原体分离株进行测序， 密歇根州的调查结果对于本项目，MDHHS将检测约400株分离株 从人类食物、动物食物、环境和水样本中提取基因组序列，并上传 结果实时到NCBI-NIH数据库。该实验室将参加GenomeTrakr网络。 参与将包括会议，电话会议，能力测试和帮助活动，如 来自网络合作伙伴的溢出测试。一名微生物学家还将参加一年一度的GenomeTrakr会议， 年度实况调查团面对面会议。参与GenomeTrakr网络将增加MDHHS的 比较和分析序列的能力和能力，这将改善和加速爆发 调查事务所该实验室定期进行单核细胞增生李斯特菌、沙门氏菌、滋贺 产毒素大肠杆菌，弯曲杆菌和弧菌，但也能够测序其他生物体，可能是 FDA的兴趣。

PROJECT SUMMARY: The primary goal of this project is to support Food and Drug Administration (FDA) by performing whole genome sequencing on isolates collected from human and or animal food for bacterial pathogens thereby assisting trace back investigations across the State of Michigan. For this project MDHHS will test approximately 400 isolates from human food, animal food, environmental and water samples by Whole Genome Sequencing and upload the results in real-time to NCBI-NIH database. The laboratory will participate in the GenomeTrakr network. Participation will include meetings, conference calls, proficiency testing and helping with activities such as overflow testing from network partners. A microbiologist will also attend an annual GenomeTrakr meeting and the annual LFFM face-to-face meeting. Participating in the GenomeTrakr network will increase MDHHS’ capabilities and ability to compare and analyze sequences that will improve and accelerate outbreak investigations. The laboratory routinely performs sequencing for Listeria monocytogenes, Salmonella, Shiga toxin-producing E.coli, Campylobacter, and Vibrio but is also able to sequence other organisms that may be of interest to FDA.