Microbiology Whole Genome Sequencing

微生物学全基因组测序

• 批准号: 10175176
• 负责人: Tracy Stiles
• 金额: $ 5.5万
• 依托单位: MASSACHUSETTS STATE DEPT OF PUB HEALTH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10175176
• 关键词: Microbiology; Whole; Genome; Sequencing

Analytical Track 4: Whole Genome Sequencing Abstract/Summary The Massachusetts State Public Health Laboratory (MASPHL) is requesting funding for Microbiology Analytical Track 4, Whole Genome Sequencing, from PAR-20-105, Laboratory Flexible Funding Model (U19). MASPHL has been a member of PulseNet for more than 20 years, and an unfunded member of GenomeTrakr for the past three years. To date, MASPHL has submitted 4,164 isolate sequences to the PulseNet database, and 12 sequences to GenomeTrakr. Among those sent to PulseNet, 20 were from food or environmental sources. Although the numbers of pathogens isolated from food samples has been low, any that are isolated have been sequenced in accordance with appropriate procedures and submitted to the national databases. By participating in this analytical track, MASPHL will have the resources necessary to focus on submitting all bacterial pathogens isolated from human and animal food products. As written in previous tracks, MASPHL has begun to redefine its relationship with the Manufactured Food Regulatory Program (MFRP) officials in the food protection program (FPP) and has begun to develop a relationship with the Animal Food Regulatory Program (AFRP) officials in the Massachusetts Department of Agricultural Resources (MDAR). In building these relationships, MASPHL has been able to enhance the quality of the human food products sampled and to focus on collecting higher risk foods that are more likely to be adulterated. And by increasing the MFRP sampling to 250 samples, and adding 100 AFRP samples, MASPHL is well positioned to identify and sequence many more pathogens than in previous years, and therefore enhance the whole national integrated food safety system.

分析途径4：全基因组测序 摘要/概要 马萨诸塞州公共卫生实验室（MASPHL）正在申请资金， 微生物学分析轨道4，全基因组测序，来自PAR-20-105，实验室 灵活的融资模式（U19）。MASPHL已经成为PulseNet的成员超过20年 在过去的三年里，他是GenomeTrakr的一名无资金支持的成员。迄今为止，MASPHL 已经向PulseNet数据库提交了4，164个分离序列， GenomeTrakr.在送往PulseNet的人中，有20人来自食品或环境来源。 虽然从食物样本中分离出的病原体数量很低， 已按照适当的程序对分离的菌株进行测序，并提交给 国家数据库。通过参与这一分析轨道，MASPHL将拥有资源， 有必要集中提交从人类和动物食品中分离出的所有细菌病原体 产品.正如在以前的曲目中所写的那样，MASPHL已经开始重新定义其与 食品保护计划（FPP）中的制造食品监管计划（MFRP）官员 并已开始与动物食品监管计划（AFRP）建立关系 马萨诸塞州农业资源部（MDAR）的官员说。在建造这些 MASPHL能够提高人类食品的质量， 抽样检查，并集中收集更有可能掺假的高风险食品。和 通过将MFRP采样增加到250个样本，并增加100个AFRP样本，MASPHL 能够比往年更好地识别和测序更多的病原体， 从而加强整个国家综合食品安全体系。