The Arizona Department of Health Services Food Safety and Food Defense Project

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Arizona Department of Health Services LFFM Grant Application Projects 1-7 Summary The Arizona Department of Health Services Laboratory (ASPHL) has capacity in Chemical, Microbiological, and Radiological testing to analyze food products for like contamination at both preparedness and regulatory levels. ASPHL is a FERN Laboratory under ISO 17025 accreditation for the analysis of food defense analytes and seeks to maintain that capability in both chemical and microbiological disciplines as well as expanding into radiochemical analysis for the duration of the 5-year project timeline. (CHEM / MICRO / RAD Tract 1). The ASPHL is the primary servicing laboratory for the testing of manufactured human food for the State of Arizona and seeks to introduce chemical food safety testing for metals and allergens on samples collected by state and county partners under the Manufactured Food Regulatory Program Standards (MFRPS) guidelines. (CHEM Tract 2). The ASPHL is partnered with Translational Genomics Research Laboratory (TGEN) for the yearly sequencing of 400 isolates of Salmonella, E. coli, Campylobacter and Listeria monocytogenes and will continue as a founding member of the FDA’s GenomeTrakr. Subrecipient TGEN has identified greater than 1000 isolates of target organisms to consider for whole genome sequencing on human food. (MICRO Tract 4). Method development is a strength of the ASPHL and the Chemistry Laboratory proposes to continue this activity with the development and validation of compliance level Allergen Testing using the MagPix System with XPonent 4.2 software with the end product being a written analytical method to submit to the FDA NPO for review. (CHEM Tract 4). The ASPHL FERN Chemistry is strong on metals analysis using ICP-MS and LC-ICP-MS and proposes to engage in a multi-laboratory validation of the Elemental Analysis manual method EAM 4.12: Analysis of Bottled Water by ICP-MS. The method will be validated two different ICP- MS platforms: an Agilent 7700 ICP-MS coupled to an Agilent 1200 uHPLC system and an Agilent 8900 ICP-triple quadruple-MS coupled with an Agilent 1260 infinity II. (CHEM SP D3).