Mechanisms of Health and Disease at the Behavioral-Biomedical Interface

摘要 行为科学和生物医学的结合是当今最具活力的科学前沿领域之一。 我们NIGMS资助的博士前培训项目的总体目标是健康和健康机制 疾病在行为-生物医学的接口，是为了培养下一代多样化的行为 科学研究人员利用严格的生物医学方法和概念框架 他们的思维和研究的边界，使他们能够在以下方面取得革命性突破 解决健康和疾病问题。该项目为行为科学博士后学生提供 在爱荷华州大学心理和脑科学系 课程作业和实验室经验。其中包括：(1)基础广泛的基础培训 行为科学包括严谨和透明，定量方法论和实验设计， 负责任地进行研究，以及健康心理学、临床心理学和 神经科学；(2)深入培训病理生理学和特定生物医学研究领域(包括 概念框架、驱动假设和实验室技术)；以及(3)指导和指导 用于开发和实施创新的独立研究计划，该计划涵盖 行为和生物医学科学。该培训计划侧重于两个主题：寿命和大脑健康 和慢性病心理生物学与妇女健康。行为导师来自心理学 和脑科学；生物医学导师来自医学院、公共卫生和护理学院。 在NIGMS支持的头3年中，我们制定了非常成功的培训计划， 对一批敬业热情的学生产生了深远而持久的影响。我们有 使用T32助学金提供的支持槽和毕业生提供的两个匹配槽 爱荷华大学招收不同类型的优秀学生，并为这一计划提供催化剂， 它已经成熟为行为科学专业的学生和 生物医学导师和他们的实验室。自项目开始以来，除了我们的8个T32资助 同学们，我们已经有25名额外的实习生利用了培训计划，包括7个不同的 学生们。我们开发了一个以职业发展为特色的研讨会和务虚会计划， 科学交流，手稿和拨款写作，以及关于前沿研究的讨论 行为-生物医学接口。总而言之，NIGMS对4名学生/年的支持回报很大 投资的红利。此续订申请要求每年续订4个时段，以便 我们可以在我们雄厚的基础上继续这一创新计划，为下一个资金周期提供资金。 该计划与公共卫生高度相关，因为行为-生物医学接口的培训将 使这些科学家能够创新地解决影响健康和疾病的机制。

Abstract The interface of behavioral and biomedical sciences is one of the most vibrant frontiers of science today. The overarching objective of our NIGMS-funded predoctoral Training Program, Mechanisms of Health and Disease at the Behavioral-Biomedical Interface, is to train the next generation of diverse behavioral science researchers to utilize rigorous biomedical methodologies and conceptual frameworks that stretch the boundaries of their thinking and research to position them to make transformative breakthroughs in addressing issues of health and disease. The program provides predoctoral behavioral science students in the University of Iowa Department of Psychological and Brain Sciences with an integrated program of coursework and laboratory experiences. These include (1) broad-based training in the fundamentals of behavioral science including rigor and transparency, quantitative methodology and experimental design, responsible conduct of research, and key issues in health psychology, clinical psychology, and neuroscience; (2) In-depth training in pathophysiology and specific biomedical research areas (including conceptual framework, driving hypotheses, and laboratory techniques); and (3) guidance and mentoring for development and implementation of an innovative independent research program that spans both behavioral and biomedical science. The Training Program focuses on two themes: Lifespan Brain Health and Psychobiology of Chronic Disease and Women's Health. Behavioral mentors are from Psychological and Brain Sciences; Biomedical mentors come from the Colleges of Medicine, Public Health, and Nursing. Over the first 3 years of NIGMS support, we have developed a highly successful Training Program that has had far-reaching and lasting influences on a group of committed and enthusiastic students. We have used the support slots provided by the T32 grant and the two matching slots provided by the Graduate College of the U. of Iowa to recruit outstanding diverse students and to provide a catalyst for this program, which has matured into a vibrant setting for scientific exchange between behavioral science students and biomedical mentors and their labs. Since the start of the program, in addition to our 8 T32 funded students, we have had 25 additional trainees take advantage of the Training Program, including 7 diverse students. We have developed a program of seminars and retreats, featuring professional development, science communication, manuscript and grant writing, and discussions of cutting-edge research at the Behavioral-Biomedical interface. In sum, the NIGMS support for 4 students/year has returned large dividends on the investment. This renewal application requests the continuation of 4 slots per year so that we can build upon our strong foundation to continue this innovative program for another funding cycle. The program is highly relevant to public health because training at the behavioral-biomedical interface will enable these scientists to innovatively address mechanisms that influence health and disease.