Mechanisms of Health and Disease at the Behavioral-Biomedical Interface

行为-生物医学界面的健康与疾病机制

• 批准号: 10176525
• 负责人: SUSAN K LUTGENDORF
• 金额: $ 22.03万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10176525
• 关键词: Behavioral; Disease; Health

Abstract The interface of behavioral and biomedical sciences is one of the most vibrant frontiers of science today. The overarching objective of our NIGMS-funded predoctoral Training Program, Mechanisms of Health and Disease at the Behavioral-Biomedical Interface, is to train the next generation of diverse behavioral science researchers to utilize rigorous biomedical methodologies and conceptual frameworks that stretch the boundaries of their thinking and research to position them to make transformative breakthroughs in addressing issues of health and disease. The program provides predoctoral behavioral science students in the University of Iowa Department of Psychological and Brain Sciences with an integrated program of coursework and laboratory experiences. These include (1) broad-based training in the fundamentals of behavioral science including rigor and transparency, quantitative methodology and experimental design, responsible conduct of research, and key issues in health psychology, clinical psychology, and neuroscience; (2) In-depth training in pathophysiology and specific biomedical research areas (including conceptual framework, driving hypotheses, and laboratory techniques); and (3) guidance and mentoring for development and implementation of an innovative independent research program that spans both behavioral and biomedical science. The Training Program focuses on two themes: Lifespan Brain Health and Psychobiology of Chronic Disease and Women's Health. Behavioral mentors are from Psychological and Brain Sciences; Biomedical mentors come from the Colleges of Medicine, Public Health, and Nursing. Over the first 3 years of NIGMS support, we have developed a highly successful Training Program that has had far-reaching and lasting influences on a group of committed and enthusiastic students. We have used the support slots provided by the T32 grant and the two matching slots provided by the Graduate College of the U. of Iowa to recruit outstanding diverse students and to provide a catalyst for this program, which has matured into a vibrant setting for scientific exchange between behavioral science students and biomedical mentors and their labs. Since the start of the program, in addition to our 8 T32 funded students, we have had 25 additional trainees take advantage of the Training Program, including 7 diverse students. We have developed a program of seminars and retreats, featuring professional development, science communication, manuscript and grant writing, and discussions of cutting-edge research at the Behavioral-Biomedical interface. In sum, the NIGMS support for 4 students/year has returned large dividends on the investment. This renewal application requests the continuation of 4 slots per year so that we can build upon our strong foundation to continue this innovative program for another funding cycle. The program is highly relevant to public health because training at the behavioral-biomedical interface will enable these scientists to innovatively address mechanisms that influence health and disease.

摘要 行为科学与生物医学科学的结合是当今最具活力的科学前沿之一。 我们的NIGMS资助的博士前培训计划的总体目标，卫生和 疾病在行为-生物医学接口，是培养下一代的多样化的行为 科学研究人员利用严格的生物医学方法和概念框架， 他们的思维和研究的界限，使他们能够在以下方面取得变革性突破： 解决健康和疾病问题。该项目为行为科学专业的预科生提供 在爱荷华州大学心理和脑科学系， 课程和实验室经验。这些措施包括：（1）基础广泛的基础培训， 行为科学，包括严谨性和透明度，定量方法和实验设计， 负责任的研究行为，以及健康心理学，临床心理学和 神经科学;（2）病理生理学和特定生物医学研究领域的深入培训（包括 概念框架、驱动假设和实验室技术）;（3）指导和指导 开发和实施一个创新的独立研究计划， 行为和生物医学科学。该培训计划侧重于两个主题：终身脑健康 以及慢性病和妇女健康的心理生物学。行为导师来自心理学 和脑科学;生物医学导师来自医学院、公共卫生学院和护理学院。 在NIGMS支持的前3年中，我们开发了一个非常成功的培训计划， 对一群忠诚而热情的学生产生了深远而持久的影响。我们有 我使用了T32赠款提供的支持插槽和毕业生提供的两个匹配插槽 美国大学爱荷华州招收优秀的多样化的学生，并为这一计划提供催化剂， 它已经成熟为行为科学学生之间的科学交流提供了一个充满活力的环境， 生物医学导师和实验室自该计划开始以来，除了我们的8 T32资助 学生，我们已经有25个额外的受训人员利用培训计划，包括7个不同的 学生我们制定了一个研讨会和务虚会计划，以专业发展为特色， 科学交流，手稿和赠款写作，以及前沿研究的讨论， 行为生物医学接口。总而言之，NIGMS对4名学生/年的支持已经恢复了 投资的红利。此更新申请要求每年延续4个插槽，以便 我们可以建立在我们强大的基础上，继续这项创新计划的另一个资金周期。 该计划是高度相关的公共卫生，因为在行为生物医学接口的培训将 使这些科学家能够创新地解决影响健康和疾病的机制。