Center of Integrated Biomedical and Bioengineering Research (CIBBR)

综合生物医学与生物工程研究中心（CIBBR）

• 批准号: 10179412
• 负责人: Rick H Cote
• 金额: $ 186.18万
• 依托单位: UNIVERSITY OF NEW HAMPSHIRE
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-01 至 2023-08-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10179412
• 关键词: Area; Award; Awareness; Behavior; Behavioral Sciences; Biomedical Engineering; Biomedical Research; Centers of Research Excellence; Clinical; Clinical Research; Collaborations; Complex; Core Facility; Development; Diagnosis; Diagnostic; Discipline; Disease; Environment; Evaluation; Faculty; Fostering; Funding; Future; Goals; Human Resources; Infrastructure; Institution; Interdisciplinary Study; Investments; Leadership; Mentors; Mission; New Hampshire; Outcome; Pathway interactions; Process; Program Development; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Science; Scientist; Secure; Structure; Supervision; Technology; Training Programs; Translations; United States National Institutes of Health; Universities; Work; base; biomedical scientist; career development; clinical development; clinically relevant; commercialization; faculty mentor; faculty research; gene interaction; human disease; improved; instrumentation; interdisciplinary approach; interest; medical schools; multidisciplinary; professor; programs; skills; tool; translational medicine

Untangling the complex interactions of genes, environment, behavior, and human diseases requires multidisciplinary perspectives and state-of-the-art technology. Recognizing this need, the University of New Hampshire (UNH) has implemented a strategy to increase the number of faculty conducting research in basic biomedical science, bioengineering, and behavioral sciences. These initiatives have been accompanied by sustained investments in research core facilities and a commitment to mentoring. In the absence of an affiliated medical school, the next step is to create a sustainable infrastructure to coordinate and integrate the research of these early stage biomedical faculty across the UNH campus and with regional partners. The objective of this application is to create a sustainable Center of Integrated Biomedical and Bioengineering Research (CIBBR) that will: (1) encourage collaborative, cross-disciplinary interactions between the biomedical and engineering sciences at UNH; (2) significantly increase the number of NIH-funded research project grants that are awarded to UNH faculty; (3) provide state-of-the-art instrumentation in well- managed core facilities; and (4) encourage collaborations that advance translational opportunities. To achieve our objective, we will pursue the following specific aims: (1) Create an university-wide center for biomedical research excellence that will enhance the ability of faculty to successfully compete for research project grants across the spectrum of biomedical and engineering sciences. We will accomplish this by: (a) establishing a Leadership Team and several supporting committees for the CIBBR to effectively coordinate and supervise biomedical and bioengineering research projects at UNH; (b) implementing a three-step career development program that prepares early stage researchers to become NIH-funded investigators; and (c) introducing comprehensive evaluations of CIBBR, as well as mechanisms for supporting additional biomedical investigators at UNH likely to secure NIH funding. (2) Acquire state-of-the-art instrumentation within an established university core facility, and provide research training programs that foster acquisition of new skills, multidisciplinary perspectives, and pathways for future clinical collaborations and commercialization. To accomplish this objective, we will: (a) acquire state-of-the art instrumentation managed by the University Instrumentation Center that is required for investigators to productively carry out their research; (b) provide structured programs to acquire new technical and leadership skills, foster multidisciplinary collaborations, and increase translational opportunities. Establishing the CIBBR at UNH will capitalize on historic strategic investments in biomedical/ bioengineering research faculty and infrastructure at UNH to create a sustainable COBRE at this institution. These outcomes will have a sustained impact on biomedical research by increasing the capacity of researchers to apply multidisciplinary approaches to develop clinically relevant diagnostic tools and treatments.

弄清楚基因、环境、行为和人类疾病之间复杂的相互作用需要 多学科视角和最先进的技术。新大学认识到这一需求 新罕布什尔州 (UNH) 实施了一项战略，以增加从事基础研究的教师数量 生物医学科学、生物工程和行为科学。这些举措的同时还伴随着 对研究核心设施的持续投资和对指导的承诺。在没有 附属医学院，下一步是创建一个可持续的基础设施来协调和整合 对整个新罕布什尔大学校园内的这些早期生物医学教师以及区域合作伙伴进行研究。 该应用程序的目标是创建一个可持续的综合生物医学和生物医学中心 生物工程研究 (CIBBR) 将：(1) 鼓励协作、跨学科互动 新罕布什尔大学生物医学和工程科学之间的合作； (2) 大幅增加NIH资助的数量 授予新罕布什尔大学教员的研究项目补助金； (3) 提供最先进的仪器仪表 管理核心设施； (4) 鼓励促进转化机会的合作。 为了实现我们的目标，我们将追求以下具体目标： (1) 创建全校生物医学卓越研究中心，提高生物医学研究能力 教师成功竞争生物医学和生物医学领域的研究项目资助 工程科学。我们将通过以下方式实现这一目标： (a) 建立一个领导团队和若干支持团队 CIBBR 委员会有效协调和监督生物医学和生物工程研究 新罕布什尔大学的项目； (b) 实施三步职业发展计划，为早期阶段做好准备 研究人员成为 NIH 资助的研究人员； (c) 引入 CIBBR 综合评估，如 以及支持 UNH 额外生物医学研究人员的机制，可能会获得 NIH 的资金。 (2) 在已建立的大学核心设施内获取最先进的仪器，并提供 研究培训计划，促进获得新技能、多学科观点和 未来临床合作和商业化的途径。为了实现这一目标，我们将： (a) 获得所需的由大学仪器中心管理的最先进的仪器 使研究人员能够高效地开展研究； (b) 提供结构化计划以获得新的 技术和领导技能，促进多学科合作，并增加转化机会。 在新罕布什尔大学建立 CIBBR 将利用生物医学/生物医学领域的历史性战略投资 UNH 的生物工程研究人员和基础设施在该机构创建可持续的 COBRE。 这些成果将通过提高生物医学研究的能力来产生持续的影响。 研究人员应用多学科方法来开发临床相关的诊断工具和治疗方法。