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Center of Integrated Biomedical and Bioengineering Research (CIBBR)

综合生物医学与生物工程研究中心（CIBBR）

基本信息

批准号：
10714950
负责人：
Rick H Cote
金额：
$ 205.31万
依托单位：
UNIVERSITY OF NEW HAMPSHIRE
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-08-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10714950
关键词：
Acceleration Advisory Committees Advocate Area Award Biomedical Engineering Biomedical Research Businesses Career Mobility Centers of Research Excellence Collaborations Communication Computational Biology Core Facility Data Science Core Dedications Development Ecosystem Educational workshop Effectiveness Environment Evaluation Faculty Faculty Recruitment Funding Goals Grant Health Human Infrastructure Institution Interdisciplinary Study Investments Knowledge Leadership Measurement Mentors Molecular New Hampshire Operations Research Outcome Performance Phase Phenotype Pilot Projects Program Development Program Evaluation Publications Research Research Infrastructure Research Personnel Research Project Grants Science Services Technology Training Translations United States National Institutes of Health Universities career career development clinical development clinically relevant diagnostic tool early-career faculty effectiveness research faculty mentor improved innovation instrument instrumentation model design multidisciplinary multiple omics operation programs recruit research faculty

项目摘要

PROJECT SUMMARY/ABSTRACT (OVERALL CORE) The University of New Hampshire’s (UNH) first COBRE: Center of Integrated Biomedical and Bioengineering Research (CIBBR) has substantially improved the biomedical and bioengineering research environment during Phase 1. These gains can be attributed to four major advancements: (a) strategic investments in Research Project and Pilot Project funding for 13 early-stage (plus 4 mid-career) UNH faculty conducting biomedical and bioengineering research; (b) dedicated mentoring of these faculty by the CIBBR Leadership Team and External Scientific Mentors; (c) major gains in research infrastructure, including the acquisition of state-of-the-art instrumentation and creation of the Molecular and Cellular Phenotyping Core, and; (d) the amplification of this infrastructure by institutional contributions to new instrumentation and addition of new technical staff within UNH’s University Instrumentation Center. The overall goal of this Phase 2 application is to further advance biomedical and bioengineering research by implementing a faculty “cluster hire” that—together with a new Data Science Core and other enhancements to research infrastructure—will accelerate rigorous, multidisciplinary research at UNH to advance the translation of biomedical discoveries to applied solutions that improve human health. We will accomplish this through the following specific aims: Aim 1. Expand and strengthen our Center’s research, administrative operations, and evaluation programs to further enhance the research environment at UNH for conducting NIH- funded biomedical and bioengineering research. Aim 2. Create a critical mass of NIH-funded investigators through recruitment of early-stage investigators supported by enhanced multi-component mentoring and career development programs for CIBBR investigators. Upon completion of Phase 2 of CIBBR, we will have strategically increased the biomedical research capacity at UNH through “cluster” hiring of both early-stage investigators and senior biomedical and bioengineering researchers and improved and expanded the mentoring of CIBBR faculty. This will be accompanied by the creation of a Data Science Core and acquisition of additional research instrumentation for the Molecular and Cellular Phenotyping Core. These actions will have a powerful and sustained impact on biomedical and bioengineering research at UNH by expanding the number of faculty performing NIH-funded research. Enhancing the capacity of UNH and external researchers to apply multidisciplinary and multi-omics approaches will increase our knowledge of basic biomedical science and bioengineering, expedite the development of clinically relevant diagnostic tools and treatments, and advance biomedical workforce training capacity in the State of NH.

项目摘要/摘要（整体核心）

项目成果

期刊论文数量（42）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Varenicline rescues nicotine-induced decrease in motivation for sucrose reinforcement.

DOI：
10.1016/j.bbr.2020.112887
发表时间：
2021-01-15
期刊：
Behavioural brain research
影响因子：
2.7
作者：
Hart E;Hertia D;Barrett ST;Charntikov S
通讯作者：
Charntikov S

Assessment of individual differences in response to acute bupropion or varenicline treatment using a long-access nicotine self-administration model and behavioral economics in female rats.

使用长期尼古丁自我给药模型和雌性大鼠的行为经济学来评估对急性安非他酮或伐尼克兰治疗反应的个体差异。

DOI：
10.1016/j.bbr.2020.112558
发表时间：
2020
期刊：
Behavioural brain research
影响因子：
2.7
作者：
Kazan,Theodore;Robison,ChristopherL;Cova,Nicole;Madore,VictoriaM;Charntikov,Sergios
通讯作者：
Charntikov,Sergios

Investigation to Minimize Electrochemical Impedance Spectroscopy Drift.

DOI：
10.1149/09707.0737ecst
发表时间：
2020
期刊：
ECS transactions
影响因子：
0
作者：
Ziino ER;Marnoto S;Halpern JM
通讯作者：
Halpern JM

Association between inflammation, lipopolysaccharide binding protein, and gut microbiota composition in a New Hampshire Bhutanese refugee population with a high burden of type 2 diabetes.

DOI：
10.3389/fnut.2022.1059163
发表时间：
2022
期刊：
FRONTIERS IN NUTRITION
影响因子：
5
作者：
Moser, Brandy;Moore, Dustin;Khadka, Bishnu;Lyons, Carrie;Foxall, Tom;Andam, Cheryl P.;Parker, Cooper J.;Ochin, Chinedu;Garelnabi, Mahdi;Sevigny, Joseph;Thomas, W. Kelley;Bigornia, Sherman;Dao, Maria Carlota
通讯作者：
Dao, Maria Carlota

Application of Voltage in Dynamic Light Scattering Particle Size Analysis.

电压在动态光散射粒度分析中的应用。

DOI：
10.3791/60257
发表时间：
2020
期刊：
Journal of visualized experiments : JoVE
影响因子：
0
作者：
Ren,Tianyu;Roberge,EmmaJ;Csoros,JohnR;Seitz,WRudolph;Balog,EvaRoseM;Halpern,JeffreyMark
通讯作者：
Halpern,JeffreyMark