Purdue Drug Discovery Training Program

摘要 普渡药物发现培训计划(PDD-TP)的目标是提供 具有全面和平衡的药物发现和研究前景的博士后学生 发展，并开发一种多学科的方法来设计新的分子 具有良好药用活性的实体，后续优化和临床前 评估。学员将选择一门综合课程，以扩大他们的知识面 和实验方法，以发现药物开发的新目标，并将 参与其主要实验室外的研究嵌入项目，以便进一步 经验和训练。受训人员还将参加计划特定活动，旨在 加强沟通、批判性思维、领导力、管理、指导、网络、 和企业家精神。活动包括一个期刊俱乐部，跨学科的正式演讲 研究，组织药物发现研讨会，吸引专家参与的独特机会 对候选药物的评估，以及参加模拟药物小组审查。每个 将努力最大限度地扩大培训计划申请者的多样性，并招募和 留住不同背景的学员。PDD-TP实习生将以全面的 在药物发现和管道开发方面的技能和经验，以及 将在他们进入生物医学劳动力大军后很长一段时间内继续为他们服务。

Abstract The objective of the Purdue Drug Discovery Training Program (PDD-TP) is to provide predoctoral students with a comprehensive and balanced perspective of drug discovery and development, and to develop a multi-disciplinary approach toward the design of novel molecular entities with promising medicinal activity, with subsequent optimization and preclinical evaluation. Trainees will take an integrated curriculum that expands their breadth of knowledge and experimental approach toward the discovery of novel targets for drug development, and will participate in a research embedding project outside their primary laboratory for further experience and training. Trainees will also participate in program-specific activities intended to enhance communication, critical thinking, leadership, management, mentorship, networking, and entrepreneurism. Activities include a journal club, formal presentations of cross-disciplinary research, organization of seminars in drug discovery, unique opportunities to engage experts in the evaluation of drug pipeline candidates, and participation in a mock drug panel review. Every effort will be made to maximize the diversity of training program applicants, and to recruit and retain trainees of diverse backgrounds. PDD-TP trainees will graduate with a comprehensive skill set and exposure to drug discovery and pipeline development, and with experiences that will continue to serve them long after they enter the biomedical workforce.