South Carolina Clinical and Translational Research Institute (SCTR)

南卡罗来纳州临床和转化研究所 (SCTR)

• 批准号: 10200510
• 负责人: KATHLEEN T. BRADY
• 金额: $ 21.61万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-04 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10200510
• 关键词: Address; Adherence; Administrative Supplement; Affect; African American; Area; Award; Behavioral; Biomedical Research; Caring; Cesarean section; Clinical Research; Clinical and Translational Science Awards; Collaborations; Communities; Computerized Medical Record; County; Detection; Development; Diagnosis; Discipline; Discipline of obstetrics; Diverse Workforce; Educational Curriculum; Environment; Evaluation; Fetal health; Focus Groups; Fostering; Foundations; Geographic Locations; Gestational Diabetes; Goals; Grant; Group Interviews; Health; Health Personnel; Health Priorities; Health system; Healthcare; Healthcare Systems; Heterogeneity; Home environment; Human; Individual; Informatics; Interdisciplinary Study; Intervention; Interview; Knowledge; Lead; Learning; Link; Literature; Maternal Health; Maternal Mortality; Measurable; Medical; Medically Underserved Area; Methodology; Methods; Minority; Mission; Monitor; Morbidity - disease rate; Mothers; Neonatal Mortality; Nurse Practitioners; Parents; Patients; Population Heterogeneity; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Pregnant Women; Premature Birth; Prenatal care; Process; Public Health; Research; Research Institute; Research Personnel; Research Training; Resources; Risk; Rural; Rural Community; Science; Secure; Severities; South Carolina; Support System; Technology; Training; Training and Infrastructure; Translational Research; Translations; Treatment outcome; United States National Institutes of Health; Universities; Ursidae Family; Vision; Vitamin D; Vitamin D Deficiency; Vitamin D supplementation; Woman; Work; adverse pregnancy outcome; care outcomes; community partnership; design; digital; experience; fetal; flexibility; health care settings; health disparity; high risk; improved; informant; innovation; innovative technologies; interest; knowledge base; maternal morbidity; maternal risk; medically underserved; method development; neonatal morbidity; neonate; outreach; parent grant; patient population; practice setting; pregnant; programs; prospective; response; rural healthcare; rural underserved; screening; social; social health determinants; success; telehealth; tool; translational pipeline

PROJECT SUMMARY – SCTR INSTITUTE Parent Award UL1-TR001450 Since 2009, the South Carolina Clinical and Translational Research Institute (SCTR) has transformed the research environment across South Carolina (SC) by creating a Learning Health System that supports high- quality clinical and translational research (CTR) and fosters collaboration and innovation. Headquartered at the Medical University of South Carolina (MUSC), SCTR has engaged stakeholders and created statewide partnerships to improve care and address social determinants of health across SC. However, greater than 75% of SC is rural, and all 46 counties contain areas designated as medically underserved, so health disparities remain an issue. Over the next five years, SCTR will strengthen its outreach to these medically underserved areas through collaboration with the Clemson University Health Extension Program and the MUSC Telehealth Center of Excellence. With a focus on implementation and dissemination as well as discovery, we will develop and demonstrate innovative technologies and outreach to improve the health of our stakeholders. We will build on prior successes and introduce innovative approaches to expand CTR across SC through the following aims: Aim 1. Extend and enhance high-quality, innovative, flexible curricula and training experiences for all levels of the CTR workforce, with particular emphasis on enhancing workforce heterogeneity and team science. Aim 2. Engage a diverse group of stakeholders as active partners in CTR to address health care priorities while enhancing the scientific knowledge base about collaboration and engagement. Aim 3. Promote greater inclusion across the full translational spectrum of research by engaging investigators from many disciplines and patient populations from diverse demographic backgrounds and geographic areas. Aim 4. Develop, demonstrate and disseminate innovative methods and processes to address barriers and accelerate the translation of research discoveries to improvements in human health that can be generalized to a variety of practice settings. Aim 5. Enhance the conduct of translational research through the development of secure and innovative informatics and digital health solutions, tools and methodologies that affect every aspect of CTR. SCTR’s vision is to be a major force in facilitating the translation of innovative science into practice to address the health priorities of the citizens of SC and beyond. To achieve this vision, SCTR’s mission is to catalyze the development of methods and technologies that lead to more efficient translation of biomedical discoveries into interventions that improve individual and public health. SCTR will serve as the statewide academic home for CTR, one that is well-integrated with SC’s healthcare systems and provides essential support for innovative, efficient, multidisciplinary research and research training. We will work within SCTR, with our partners across SC and with the CTSA Consortium to realize this vision.

项目摘要 - SCTR研究所父母奖UL1-TR001450 自2009年以来，南卡罗来纳州的临床和转化研究所（SCTR）已经改变了 通过建立一个支持高级的学习卫生系统，南卡罗来纳州（SC）的研究环境 优质的临床和转化研究（CTR）以及培养合作与创新。总部位于 南卡罗来纳州医科大学（MUSC），SCTR已与利益相关者订婚并在全州创建了 合作伙伴关系，以改善护理和解决社会决定者的健康状况。但是，大于75％ SC的粗糙，所有46个县都包含指定为医学欠缺的地区，因此健康差异 仍然是一个问题。在接下来的五年中，SCTR将加强其对这些医学服务不足的宣传 通过与克莱姆森大学健康扩展计划和MUSC远程医疗合作的区域 卓越中心。侧重于实施和传播以及发现，我们将发展 并展示创新的技术和推广，以改善利益相关者的健康。我们将建造 关于先前的成功并引入创新方法，以通过以下目的扩展SCTR的CTR： 目标1。扩展并增强各个级别的高质量，创新，灵活的课程和培训经验 CTR劳动力，特别着重于增强劳动力异质性和团队科学。 AIM 2。与CTR中的一群利益相关者一起作为积极合作伙伴，以解决医疗保健的重点 增强有关协作和参与的科学知识基础。 目标3。通过吸引研究人员，促进整个研究的全部翻译范围的更多信息 来自潜水员人群背景和地理区域的许多学科和患者人群。 目标4。开发，演示和传播创新方法和流程，以解决障碍和 加速研究发现的翻译以改善人类健康，这可以推广到 各种练习环境。 目标5。通过开发安全和创新的发展，增强翻译研究的行为 信息和数字健康解决方案，影响CTR各个方面的工具和方法。 SCTR的愿景是成为促进创新科学转化为实践的主要力量，以解决 SC及以后的公民的健康优先事项。为了实现这一愿景，SCTR的使命是催化 开发方法和技术，从而导致生物医​​学发现更有效地翻译成 改善个人和公共卫生的干预措施。 SCTR将作为全州范围的学术室 CTR，与SC的医疗保健系统完善的CTR，为创新，为创新， 高效，多学科研究和研究培训。我们将在SCTR中与我们的合作伙伴一起工作 SC和CTSA联盟实现这一愿景。