South Carolina Clinical & Translational Research Institute (SCTR)

项目摘要-SCTR协会家长奖UL1-TR001450 自2009年以来，南卡罗来纳州临床和翻译研究所(SCTR)转变了 整个南卡罗来纳州(SC)的研究环境，通过创建支持高 高质量的临床和转化性研究(CTR)，并促进协作和创新。总部设在 南卡罗来纳医科大学(MUSC)已经与利益相关者接触，并在全州范围内创建了 伙伴关系，以改善护理和解决整个SC健康的社会决定因素。然而，大于 南卡罗来纳州75%的人是农村人，所有46个县都有被指定为医疗服务不足的地区，所以健康 差距仍然是一个问题。在接下来的五年里，SCTR将加强对这些医学领域的宣传 通过与克莱姆森大学健康推广计划和 南加州大学远程医疗卓越中心。重点是实施和传播以及 发现，我们将开发和展示创新技术和推广，以改善 我们的利益相关者。我们将在以往成功的基础上，引入创新的方法来扩大CTR 通过以下目标覆盖整个SC： 目标1.推广和加强各级高质量、创新、灵活的课程和培训经验 CTR员工队伍的管理，特别强调加强员工队伍的异质性和团队科学。 目标2.使不同的利益攸关方群体成为CTR的积极合作伙伴，以解决卫生保健优先事项 同时加强关于协作和参与的科学知识库。 目标3.通过吸引调查人员，促进研究全翻译谱系的更大包容性 来自许多学科和来自不同人口背景和地理位置的患者群体 区域。 目标4.制定、示范和传播创新方法和程序，以解决障碍和 加速将研究发现转化为可推广的人类健康改善 不同的练习环境。 目标5.通过开发安全和创新的方法加强翻译研究的开展 影响CTR方方面面的信息学和数字健康解决方案、工具和方法。 SCTR的愿景是成为促进创新科学转化为实践的主要力量，以 解决南卡罗来纳州及其他地区公民的健康优先事项。为了实现这一愿景，SCTR的使命是 促进方法和技术的发展，从而更有效地翻译生物医学 对改善个人和公共健康的干预措施的发现。SCTR将作为全州范围内的 CTR的学术之家，与SC的医疗系统良好集成，并提供必要的 支持创新、高效、多学科的研究和研究培训。我们将在SCTR内工作， 与我们整个SC的合作伙伴和CTSA联盟一起实现这一愿景。

PROJECT SUMMARY – SCTR INSTITUTE Parent Award UL1-TR001450 Since 2009, the South Carolina Clinical and Translational Research Institute (SCTR) has transformed the research environment across South Carolina (SC) by creating a Learning Health System that supports high- quality clinical and translational research (CTR) and fosters collaboration and innovation. Headquartered at the Medical University of South Carolina (MUSC), SCTR has engaged stakeholders and created statewide partnerships to improve care and address social determinants of health across SC. However, greater than 75% of SC is rural, and all 46 counties contain areas designated as medically underserved, so health disparities remain an issue. Over the next five years, SCTR will strengthen its outreach to these medically underserved areas through collaboration with the Clemson University Health Extension Program and the MUSC Telehealth Center of Excellence. With a focus on implementation and dissemination as well as discovery, we will develop and demonstrate innovative technologies and outreach to improve the health of our stakeholders. We will build on prior successes and introduce innovative approaches to expand CTR across SC through the following aims: Aim 1. Extend and enhance high-quality, innovative, flexible curricula and training experiences for all levels of the CTR workforce, with particular emphasis on enhancing workforce heterogeneity and team science. Aim 2. Engage a diverse group of stakeholders as active partners in CTR to address health care priorities while enhancing the scientific knowledge base about collaboration and engagement. Aim 3. Promote greater inclusion acrossthe full translational spectrumof research by engaging investigators from many disciplines and patient populations from diverse demographic backgrounds and geographic areas. Aim 4. Develop, demonstrate and disseminate innovative methods and processes to address barriers and accelerate the translation of research discoveries to improvements in human health that can be generalized to a variety of practice settings. Aim 5. Enhance the conduct of translational research through the development of secure and innovative informatics and digital health solutions, tools and methodologies that affect every aspect of CTR. SCTR’s vision is to be a major force in facilitating the translation of innovative science into practice to address the health priorities of the citizens of SC and beyond. To achieve this vision, SCTR’s mission is to catalyze the development of methods and technologies that lead to more efficient translation of biomedical discoveries into interventions that improve individual and public health. SCTR will serve as the statewide academic home for CTR, one that is well-integrated with SC’s healthcare systems and provides essential support for innovative, efficient, multidisciplinary research and research training. We will work within SCTR, with our partners across SC and with the CTSA Consortium to realize this vision.