Southern Consortium Node of the Clinical Trials Network

摘要 NIDA临床试验网络（CTN）为评估创新方法提供了理想的平台， 在各种治疗环境中加强技术驱动的比较有效性试验。此续订 该应用程序建立在CTN南方联盟节点（SCN）多年成功的基础上。由于我们 成立于2000年，我们建立并维持了一支杰出的跨专业成瘾专家团队 治疗和研究，进行了一系列管理良好的临床试验，并通过 传统的沟通渠道，如专业会议和同行评审的出版物。我们 认识到，为了产生有意义的人口影响，治疗必须很好地整合到 医疗实践和治疗提供系统。通过这次更新，我们利用最近的成功， 在广泛的医疗保健环境中进行临床试验，利用新的技术基础 筛查和治疗物质使用障碍（SUD）的方法。急性护理管理 医疗环境中的SUD（即筛查、短暂干预和转诊的SBIRT策略） 不足以解决SUD患者的长期护理需求，这些患者经常以复发为标志。我们 提出一个更全面的方法，包括慢性病护理管理，基于更广泛的 翻译的观点，使用新的，技术驱动的战略，以改善筛选，增加交付， 短期干预的有效性，优化专科护理转诊，并制定系统，以解决慢性 许多SUD的复发过程。我们强调探索不仅有效， 还具有成本效益，以促进临床实践环境的采用。我们为网络带来了一个 在药物使用筛查、干预提供和转诊整合方面具有专业知识的研究团队 在初级保健和其他卫生保健环境中。在成瘾研究的现有优势的基础上， MUSC，我们已经组建了一个多学科的团队，在成瘾治疗，初级保健， 生物信息学、移动的健康、医疗成本分析和临床研究的重点调查 在各种环境中对SUD进行有效的筛查和治疗干预。我们非常适合 继续作为CTN联盟的积极成员，探索高效和有效的方法， 成瘾治疗纳入主流医疗保健。为此，我们将迎接新的挑战， 在不断变化的医疗保健系统中增加机会的优势。

Abstract The NIDA Clinical Trials Network (CTN) offers the ideal platform to evaluate innovative methods, thereby potentiating technology-driven comparative effectiveness trials in a variety of treatment settings. This renewal application builds upon years of success in the Southern Consortium Node (SCN) of the CTN. Since our inception in 2000, we have built and sustained an outstanding team of inter-professional experts in addictions treatment and research, conducted an array of well-managed clinical trials, and disseminated findings through traditional communication channels, such as professional conferences and peer-reviewed publications. We recognize that in order to have meaningful population impact, treatments must be well integrated into healthcare practices and treatment delivery systems. With this renewal, we capitalize on recent successes in conducting clinical trials in a wide range of healthcare settings that make use of new technologically based methods to screen and treat individuals with substance use disorders (SUDs). Acute care management of SUDs within medical settings (i.e. SBIRT strategies to screen, briefly intervene, and refer to treatment) insufficiently addresses the chronic care needs of SUD patients that are so often marked by relapse. We propose a more comprehensive approach, including chronic care management, based on a broader translational view, using novel, technology-driven strategies to improve screening, increase delivery and efficacy of brief interventions, optimize referrals to specialty care, and develop systems to address the chronic relapsing course of many SUDs. We emphasize the exploration of approaches that are not only effective, but also cost-effective, so as to promote adoption into clinical practice settings. We bring to the network a research team with expertise in the integration of substance use screening, intervention delivery, and referral within primary care and other health care settings. Building on existing strengths in addictions research at MUSC, we have assembled a multi-disciplinary team with expertise in addiction treatment, primary care, bioinformatics, mobile health, health care cost analysis and clinical research to focus on the investigation of effective screening and treatment interventions for SUDs in a variety of settings. We are ideally suited to continue as active members of the CTN consortium in exploring efficient and effective ways to integrate addictions treatment into mainstream medical care. In doing so, we will meet new challenges and take advantage of growing opportunities within the changing healthcare system.