CTSA INFRASTRUCTURE FOR AIDS RESEARCH

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目人员提供的补助金。 南卡罗来纳州临床和转化研究所 (SCTR) 的目标是在南卡罗来纳医科大学 (MUSC) 创建一个可持续发展的家园，以推进临床和转化研究作为一个独特的学科，并促进跨学科的合作。总体方法侧重于：(1) 实现生物医学科学的重要进展，创造发现机会；(2) 消除障碍，促进跨学科边界的知识、经验和专业知识的联系；(3) 提供培训和指导经验，以加强具有不同培训和背景的临床和转化研究人员的渠道；(4) 促进社区参与快速增长的全州人口，而许多系统服务不足，以改善他们的参与和健康结果。 MUSC 拥有领导全州成功临床和转化研究工作的长期经验。它是校外资助研究活动的领先国家机构，并拥有丰富的研究培训组合。 SCTR 成立于 2007 年，其愿景是通过与学术和社区附属机构的牢固关系，成为变革 MUSC 和全州研究文化的“变革推动者”。目前已经取得了巨大进展，包括制定了临床和转化研究方面的机构 K12 职业发展计划、实施了在前两轮竞争中资助 29 个项目的试点项目计划，以及与 NIH 资助的范德比尔特大学 CTSA 建立了强有力的合作，以协助 SCTR 生物医学信息学计划。加入国家 CTSA 联盟将通过进一步促进 (1) 生物医学信息学系统的开发和互操作性，(2) 积极交流循证医学和社区参与的最佳流程和最佳实践，(3) 临床和转化科学作为一门学科和职业道路的进步来加速进展； (4) 在制定区域和国家研究议程和卫生政策方面共享知识、经验和集体影响力，旨在产生 NIH 路线图所设想的变革性结果。相关性（参见说明）：SCTR 将汇集科学家、临床医生和非专业人士来解决通常影响南卡罗来纳州公民的疾病。 SCTR 将协调全州范围内的资源和专业知识，以实现高效、创新的研究方法。通过 SCTR，新一代研究人员将接受培训，与社区成员合作跨多个学科开展工作，以便科学发现具有相关性

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The goal of the South Carolina Clinical and Translational Research Institute (SCTR) is to create a sustainable home at the Medical University of South Carolina (MUSC) to advance clinical and translational research as a distinct discipline and facilitate collaboration across multiple disciplines. The overall approach focuses on: (1) implementing important advances in biomedical science to create opportunities for discovery, (2) removing barriers to facilitate the linkage of knowledge, experience and expertise across disciplinary boundaries, (3) providing training and mentoring experiences to enhance the pipeline for clinical and translational researchers with diverse training and backgrounds, and (4) fostering community engagement with a rapidly growing statewide population that is underserved by many systems to improve their participation and health outcomes. MUSC has long-standing experience leading successful clinical and translational research efforts that span the state. It is the leading state institution in extramurally funded research activities and has a rich research training portfolio. SCTR was established in 2007 with the vision that it would be the "agent of change" in transforming the research culture at MUSC and statewide via strong relationships with academic and community-based affiliates. Great progress has already been made including the development of an institutional K12 Career Development Program in Clinical and Translational Research, implementation of a pilot project program that funded 29 projects in the first two competitive rounds, and establishment of a robust collaboration with the NIH-funded CTSA at Vanderbilt University for assistance in the SCTR Biomedical Informatics Program. Joining the national CTSA Consortium will accelerate progress by further facilitating (1) development and interoperability of biomedical informatics systems, (2) active exchange of best processes and best practices in evidence-based medicine and community engagement, (3) advancement of clinical and translational science as a discipline and career path; and (4) shared knowledge, experience and collective influence in setting regional and national research agendas and health policy designed to generate the transformative results envisioned by the NIH Roadmap. RELEVANCE (See instructions): SCTR will bring together scientists, clinicians and the lay community to address diseases that commonly impact the citizens of South Carolina. SCTR will coordinate resources and expertise statewide in efficient, innovative approaches to research. Through SCTR, a new generation of researchers will be trained to work across multiple disciplines in collaboration with community members so that scientific discovery is relevant