Wisconsin ADRC Recruitment and Engagement of Veterans into Alzheimer's Disease and Alzheimer's Disease Related Dementiaz (AD/ADRD) Studies Program

项目摘要/摘要 与普通人群相比，美国退伍军人患痴呆症的风险更高，可能 部分原因是创伤性脑损伤和创伤后应激障碍的暴露增加。进一步研究 需要更好地了解这些与服务相关的风险因素如何与其他阿尔茨海默病相互作用 (Ad)加速痴呆症风险的风险因素。这种研究对于确定预防AD的策略是必要的 在退伍军人中。建议的“威斯康星州阿尔茨海默病研究中心(ADRC)招募和 退伍军人参与阿尔茨海默病及阿尔茨海默病相关痴呆的研究 该计划将与麦迪逊退伍军人事务部(VA)医院、退伍军人事务部 研究、教育和临床中心(GRECC)、相关的退伍军人事务部社区项目和威斯康星州 ADRC核心，以提高退伍军人对临床研究的参与度、招募和留存 与退伍军人相关的痴呆症危险因素和潜在的AD预防策略。该计划将建立在 威斯康星州ADRC使用社区参与模式来增加招聘和留住 来自非洲裔美国人和美国原住民社区的个人进入ADRC临床核心和相关组织 学习。此外，拟议的方案将借鉴麦迪逊退伍军人管理局调查人员和 来自退伍军人参与小组的意见，以确保战略和资源反映退伍军人的利益。 通过该计划制定的成功原则和流程将在国家研究所共享 关于老龄化ADRC计划及相关研究。

PROJECT SUMMARY/ABSTRACT Compared to the general population, United States military Veterans are at increased risk for dementia, possibly due in part to increased exposure to traumatic brain injury and post-traumatic stress disorder. Further research is needed to better understand how these service-related risk factors interact with other Alzheimer's disease (AD) risk factors to accelerate dementia risk. Such research is necessary to identify strategies for AD prevention in Veterans. The proposed “Wisconsin Alzheimer's Disease Research Center (ADRC) Recruitment and Engagement of Veterans into Alzheimer's Disease and Alzheimer's Disease Related Dementias Studies Program” will work with stakeholders across the Madison Veterans Affairs (VA) Hospital, the VA Geriatric Research, Education and Clinical Center (GRECC), related VA community-based programs, and the Wisconsin ADRC Cores to improve engagement, recruitment, and retention of Veterans into clinical studies identifying dementia risk factors and potential AD prevention strategies relevant to Veterans. The program will build upon the community engagement models used by the Wisconsin ADRC to increase recruitment and retention of individuals from African American and Native American communities into the ADRC Clinical Core and related studies. In addition, the proposed program will draw upon the experiences of Madison VA investigators and input from the Veteran Engagement Group to ensure that strategies and resources reflect Veteran interests. Successful principles and processes developed through this program will be shared across the National Institute on Aging ADRC Program and related studies.