Wisconsin ADRC Recruitment and Engagement of Veterans into Alzheimer's Disease and Alzheimer's Disease Related Dementiaz (AD/ADRD) Studies Program

项目总结/摘要 与一般人群相比，美国退伍军人患痴呆症的风险增加，可能是因为他们的年龄和性别。 部分原因是创伤性脑损伤和创伤后应激障碍的暴露增加。进一步研究 需要更好地了解这些与服务相关的风险因素如何与其他阿尔茨海默病相互作用 (AD)风险因素加速痴呆风险。这种研究对于确定AD预防策略是必要的 在退伍军人。拟议中的“威斯康星州阿尔茨海默病研究中心（ADRC）招募和 退伍军人参与阿尔茨海默病和阿尔茨海默病相关痴呆研究 计划”将与利益相关者在整个麦迪逊退伍军人事务部（VA）医院，VA老年 研究，教育和临床中心（GRECC），相关的VA社区为基础的计划，和威斯康星州 ADRC核心，以改善参与，招聘，并保留退伍军人进入临床研究， 痴呆症的危险因素和潜在的AD预防策略相关的退伍军人。该计划将建立在 威斯康星州ADRC使用的社区参与模式，以增加招聘和保留 来自非洲裔美国人和美洲原住民社区的个人进入ADRC临床核心和相关 问题研究此外，拟议的计划将借鉴麦迪逊VA调查人员的经验， 退伍军人参与小组的意见，以确保战略和资源反映退伍军人的利益。 通过该计划制定的成功原则和流程将在整个国家研究所共享 关于老龄化ADRC计划和相关研究。

PROJECT SUMMARY/ABSTRACT Compared to the general population, United States military Veterans are at increased risk for dementia, possibly due in part to increased exposure to traumatic brain injury and post-traumatic stress disorder. Further research is needed to better understand how these service-related risk factors interact with other Alzheimer's disease (AD) risk factors to accelerate dementia risk. Such research is necessary to identify strategies for AD prevention in Veterans. The proposed “Wisconsin Alzheimer's Disease Research Center (ADRC) Recruitment and Engagement of Veterans into Alzheimer's Disease and Alzheimer's Disease Related Dementias Studies Program” will work with stakeholders across the Madison Veterans Affairs (VA) Hospital, the VA Geriatric Research, Education and Clinical Center (GRECC), related VA community-based programs, and the Wisconsin ADRC Cores to improve engagement, recruitment, and retention of Veterans into clinical studies identifying dementia risk factors and potential AD prevention strategies relevant to Veterans. The program will build upon the community engagement models used by the Wisconsin ADRC to increase recruitment and retention of individuals from African American and Native American communities into the ADRC Clinical Core and related studies. In addition, the proposed program will draw upon the experiences of Madison VA investigators and input from the Veteran Engagement Group to ensure that strategies and resources reflect Veteran interests. Successful principles and processes developed through this program will be shared across the National Institute on Aging ADRC Program and related studies.