Network on Education, Biosocial Pathways, and Dementia across Diverse Populations

不同人群的教育、生物社会途径和痴呆症网络

• 批准号: 10666492
• 负责人: Sanjay Asthana
• 金额: $ 37.67万
• 依托单位: UNIV OF MARYLAND, COLLEGE PARK
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-15 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10666492
• 关键词: Alzheimer' s Disease Pathway; Alzheimer' s disease pathology; Alzheimer' s disease related dementia; Attention; Award; Behavior; Behavioral; Biological; Biology; Biosocial; Black race; Brain Pathology; Clinical; Clinical Treatment; Collaborations; Communication; Communities; Complex; Data; Dementia; Development; Discipline; Disease; Disparity; Education; Educational workshop; Elderly; Ethnic Origin; Funding; Genetic; Goals; Grant; Grant Review; Health behavior; High Prevalence; Inflammatory; Intervention; Joints; Leadership; Life; Link; Longitudinal Studies; Measures; Methods; Neurocognitive; Pathway interactions; Pattern; Pilot Projects; Policies; Population Heterogeneity; Population Study; Race; Reporting; Research; Research Personnel; Research Project Grants; Research Support; Risk; Role; Scholarship; Science; Scientific Advances and Accomplishments; Scientist; Shapes; Techniques; Testing; Training; United States; United States National Institutes of Health; Work; Writing; aged; college; data resource; dementia risk; ethnic difference; ethnic health disparity; health disparity populations; high school; meetings; member; middle age; population health; prevent; psychologic; racial difference; racial health disparity; recruit; resilience; social; social media; socioeconomics; success; tool; user-friendly; web page; webinar; working group

PROJECT SUMMARY Despite the high prevalence of Alzheimer’s Disease and Related Dementias (ADRD), we have yet to develop clinical interventions that can substantially slow or reverse the course of dementia. One of the most powerful determinants of ADRD, educational attainment, remains poorly understood. To advance scientific understanding of how, why, and for whom education relates to ADRD, we propose to build an interdisciplinary network of ADRD scientists whose joint expertise is vital to achieving NIA’s goal to reduce educational disparities in ADRD: population health scientists, with their expertise in the behaviors that shape dementia risk and resilience, and ADRD researchers, with their expertise in the biology and neurocognitive aspects of ADRD. Our Network will advance scientific understanding of how education relates to ADRD disparities by exploring the socioeconomic, social, psychological, and biological mechanisms that shape resilience and risk and if these patterns differ by race and ethnicity. Identifying and clarifying mechanisms is needed to inform interventions to reduce educational disparities in ADRD. The NIH-funded longitudinal population-based studies that form the core data resources linked to this network, and the Network’s leadership, are well suited to meet the broader scientific aim. We will advance education and ADRD science by establishing an interdisciplinary Network of new, emerging, and established ADRD scientists who will apply cutting-edge methods and techniques from their respective disciplines to answer complex questions about the education—ADRD relationship. Our Network will facilitate research collaboration and professional development via annual meetings, small working groups, pilot awards, and workshops. Annual meetings and working groups will provide venues for new and emerging ADRD scholars to develop collaborations with established ADRD scholars across disciplinary boundaries and pilot awards will support collaborative research projects. Workshops will provide introductory training in ADRD science and professional development in grant writing, and science communication. We will disseminate Network products to the scientific and broader policy community that are discoverable and user-friendly. We will develop a Network webpage and social media accounts to share recorded webinars, Network-developed tools and user guides, solicit pilot projects, and highlight the work of our Network members through infographics and short data briefs. The Network will be led by an interdisciplinary leadership team with expertise in the data that undergirds the Network, population health disparities, and the clinical and biological underpinnings of ADRD, thus bridging the social, clinical, and ADRD sciences, as well as the three nodes critical to building our Network: ADRD, education, and diverse populations. Our Network will develop new and emerging ADRD scholars, quickly integrate them into the field, and facilitate and elevate their scholarship to have high and sustained impact in education and ADRD.

项目摘要 尽管阿尔茨海默病和相关痴呆症（ADRD）的发病率很高，但我们还没有开发出 临床干预可以大大减缓或逆转痴呆症的进程。一个最强大的 ADRD的决定因素，教育程度，仍然知之甚少。为了促进科学理解 如何，为什么，以及为谁教育涉及到ADRD，我们建议建立一个跨学科的ADRD网络 科学家，他们的联合专业知识是实现NIA的目标，以减少在ADRD教育差距至关重要： 人口健康科学家，在影响痴呆症风险和复原力的行为方面拥有专业知识，以及 ADRD研究人员，他们在ADRD的生物学和神经认知方面的专业知识。我们的网络将 通过探索教育与ADRD差异之间的关系， 社会经济，社会，心理和生物机制，塑造弹性和风险，如果这些 模式因种族和民族而异。需要确定和澄清各种机制，以便为干预措施提供信息， 减少ADRD中的教育差距。NIH资助的基于人群的纵向研究构成了 与该网络相连的核心数据资源以及该网络的领导地位非常适合满足更广泛的需求， 科学目的。我们将通过建立一个跨学科网络来推进教育和ADRD科学 新的，新兴的和成熟的ADRD科学家谁将应用尖端的方法和技术 从各自的学科，回答有关教育ADRD关系的复杂问题。我们 网络将通过年度会议、小型会议和 工作组、试点奖和讲习班。年度会议和工作组将为新的 新兴的ADRD学者与跨学科的ADRD学者开展合作 边界和试点奖将支持合作研究项目。研讨会将提供介绍性的 在ADRD科学和专业发展的培训，在赠款写作和科学交流。我们将 向科学界和更广泛的政策界传播网络产品， 用户友好。我们将开发一个网络网页和社交媒体帐户，以分享录制的网络研讨会， 网络开发的工具和用户指南，征求试点项目，并强调我们的网络成员的工作 通过信息图表和简短的数据简报。该网络将由一个跨学科领导小组领导， 在支撑网络的数据、人口健康差异以及临床和生物学方面的专业知识 ADRD的基础，从而桥接社会，临床和ADRD科学，以及三个关键节点 建立我们的网络：ADRD，教育和多样化的人群。我们的网络将发展新的和新兴的 ADRD学者，迅速将他们融入该领域，并促进和提升他们的学术水平， 在教育和ADRD方面的持续影响。