Training Program in Biochemistry, Cell and Development Biology

生物化学、细胞和发育生物学培训项目

基本信息

  • 批准号:
    10190967
  • 负责人:
  • 金额:
    $ 34.13万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2020
  • 资助国家:
    美国
  • 起止时间:
    2020-07-01 至 2025-06-30
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY This is a new application for a T32 to support predoctoral training in Biochemistry, Cell and Developmental Biology (BCDB) at Emory University. The award will replace the current T32 training program, which is in its 29th year, and has successfully trained a diverse cohort of students for the biomedical research workforce. We are requesting 7 positions and anticipate the duration of appointment will be 12-24 months. The mission of the BCDB training program is to provide an outstanding training environment through evidenced-based learning approaches and top caliber research mentors for development of our Ph.D. level workforce in academic-, industry- and government-based research careers as well as other biomedical research-related careers. This mission will be accomplished through a core curriculum that includes discussion-based, active learning approaches to the fundamental principles of biological processes at the biochemical and cellular level and development of oral and written presentation skills through classroom and seminar experiences. In addition, the importance of rigor and reproducibility in biomedical research is emphasized throughout the training with a required course as well as emphasizing this training as part of the courses, seminars and journal clubs. The objectives of the training program are to use these approaches to provide Ph.D. scientists with the necessary skills in critical thinking, experimental design and quantitative approaches as they acquire an understanding of how to conduct their work in a manner that is responsible, rigorous and reproducible. The program has an inclusive environment and is active in the recruitment and retention of students from diverse backgrounds. There is also an established focus on training the faculty mentors to provide the most outstanding training environment possible. The program also provides unique training opportunities to students supported by the proposed T32 training program through their responsibilities in running an innovative journal club as well as their role in organizing the two annual BCDB symposia; one which highlights career opportunities for Ph.D. graduates. We plan to continue our track record of training success while also introducing new and innovative aspects to the training together with mechanisms to evaluate both student and program outcomes.
项目摘要 这是T32的新应用程序,以支持生物化学,细胞和发育的博士前培训 生物学(BCDB)在埃默里大学。该奖项将取代目前的T32培训计划,这是在其第29届 一年,并成功地培养了一批多样化的学生为生物医学研究的劳动力。我们 申请7个职位,预计任期为12-24个月。BCDB的使命 培训计划是通过循证学习提供一个优秀的培训环境 方法和高素质的研究导师为我们的博士发展。学术水平的劳动力, 行业和政府为基础的研究事业,以及其他生物医学研究相关的职业。这 使命将通过核心课程完成,其中包括基于讨论的主动学习 在生物化学和细胞水平上接近生物过程的基本原理, 通过课堂和研讨会的经验,发展口头和书面表达技能。此外该 生物医学研究中的严谨性和可重复性的重要性在整个培训中得到了强调, 必修课程,并强调这种培训作为课程,研讨会和期刊俱乐部的一部分。的 培训计划的目标是使用这些方法提供博士学位。科学家们必须 批判性思维,实验设计和定量方法的技能,因为他们了解 如何以负责任、严谨和可重复的方式开展工作。该计划有一个 包容性的环境,并积极招聘和留住来自不同背景的学生。那里 也是一个既定的重点培训教师导师提供最优秀的培训环境 可能该计划还提供了独特的培训机会,以学生所提出的T32 培训计划,通过他们的责任,在运行一个创新的期刊俱乐部,以及他们的作用, 组织两个年度BCDB研讨会;其中一个突出了博士的职业机会。毕业生我们 我们计划继续保持我们成功的培训记录,同时也为 培训与机制一起评估学生和计划的成果。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Lawrence H. Boise其他文献

Ectopic NSD2 Remodels H3K36me2 and DNA Methylation to Promote Oncogenic Gene Expression in Multiple Myeloma
  • DOI:
    10.1182/blood-2024-210929
  • 发表时间:
    2024-11-05
  • 期刊:
  • 影响因子:
  • 作者:
    Robert M Chavez;Doris R. Powell;Kiran Lakhani;John Attelah;Erin Flynt;Terry Connolly;Mark Hamilton;George Mulligan;Daniel Auclair;Jonathan Keats;Paula M Vertino;Lawrence H. Boise;Sagar Lonial;Karen N Conneely;Benjamin G. Barwick
  • 通讯作者:
    Benjamin G. Barwick
Targeting ABCD1-ACOX1-MET/IGF1R axis suppresses multiple myeloma
靶向 ABCD1-ACOX1-MET/IGF1R 轴抑制多发性骨髓瘤
  • DOI:
    10.1038/s41375-025-02522-9
  • 发表时间:
    2025-01-30
  • 期刊:
  • 影响因子:
    13.400
  • 作者:
    Zhannan Han;Zhibo Yan;Zhehan Ma;Yihui Wang;Maja Beus;Junqi Lu;Loren B. Weidenhammer;Kiran Lakhani;Jingyun Lee;John D. Civils;Cristina M. Furdui;Liang Liu;Jian Wu;Yubin Kang;Erhard Bieberich;Lawrence H. Boise;Mikhail A. Nikiforov
  • 通讯作者:
    Mikhail A. Nikiforov
Tumor Intrinsic and Antigen-Independent Resistance Mechanisms to Bispecific T Cell Engagers in Multiple Myeloma
  • DOI:
    10.1182/blood-2024-211979
  • 发表时间:
    2024-11-05
  • 期刊:
  • 影响因子:
  • 作者:
    Holly Lee;Sungwoo Ahn;Mansour Poorebrahim;David Jung;Sacha Benaoudia;Noémie Leblay;Francesco Maura;Lawrence H. Boise;Paola Neri;Nizar J. Bahlis
  • 通讯作者:
    Nizar J. Bahlis
Genomic Determinants of Clinical Outcomes in Multiple Myeloma with t(11;14)(CCND1;IGH) Treated with Venetoclax
  • DOI:
    10.1182/blood-2024-204071
  • 发表时间:
    2024-11-05
  • 期刊:
  • 影响因子:
  • 作者:
    Marcella Kaddoura;J Erin Wiedmeier-Nutor;Vikas A. Gupta;Bachisio Ziccheddu;Suganti Shivaram;Hongwei Tang;Rodrigo Fonseca;Michael Durante;Shannon M Matulis;Tomas Jelinek;Ola Landgren;Constantine S Mitsiades;P. Leif Bergsagel;Esteban Braggio;Lawrence H. Boise;Rafael Fonseca;Shaji Kumar;Francesco Maura;Linda B. Baughn
  • 通讯作者:
    Linda B. Baughn
Tumor-Immune Architecture and the Regulation of Antigen-Specific T-Cell Infiltration in Multiple Myeloma and Premalignant Plasma Cell Disorders
  • DOI:
    10.1182/blood-2022-169558
  • 发表时间:
    2022-11-15
  • 期刊:
  • 影响因子:
  • 作者:
    Hope Robinson;Nancy Villa;David L Jaye;Ajay K. Nooka;Alyssa Duffy;Samuel McCachren;Julia Manalo;Jeffrey M. Switchenko;Ava Horvat;Vaunita C Parihar;Jingjing Gong;Yan Liang;Geoffrey Smith;Vikas A Gupta;Lawrence H. Boise;Jonathan L. Kaufman;Craig C Hofmeister;Nisha Joseph;Sagar Lonial;Kavita Dhodapkar
  • 通讯作者:
    Kavita Dhodapkar

Lawrence H. Boise的其他文献

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{{ truncateString('Lawrence H. Boise', 18)}}的其他基金

Defining the landscape of structural alterations in African American Multiple Myeloma
定义非裔美国人多发性骨髓瘤的结构改变
  • 批准号:
    10510606
  • 财政年份:
    2022
  • 资助金额:
    $ 34.13万
  • 项目类别:
Defining the landscape of structural alterations in African American Multiple Myeloma
定义非裔美国人多发性骨髓瘤的结构改变
  • 批准号:
    10651845
  • 财政年份:
    2022
  • 资助金额:
    $ 34.13万
  • 项目类别:
Training Program in Biochemistry, Cell and Molecular Biology
生物化学、细胞和分子生物学培训项目
  • 批准号:
    10393719
  • 财政年份:
    2020
  • 资助金额:
    $ 34.13万
  • 项目类别:
Training Program in Biochemistry, Cell and Development Biology
生物化学、细胞和发育生物学培训项目
  • 批准号:
    10626006
  • 财政年份:
    2020
  • 资助金额:
    $ 34.13万
  • 项目类别:
Training Program in Biochemistry, Cell and Development Biology
生物化学、细胞和发育生物学培训项目
  • 批准号:
    10409738
  • 财政年份:
    2020
  • 资助金额:
    $ 34.13万
  • 项目类别:
The Role of CD86 in Multiple Myeloma
CD86 在多发性骨髓瘤中的作用
  • 批准号:
    9198507
  • 财政年份:
    2015
  • 资助金额:
    $ 34.13万
  • 项目类别:
Novel Roles for Effector Procaspases
效应器蛋白酶原的新作用
  • 批准号:
    9042395
  • 财政年份:
    2014
  • 资助金额:
    $ 34.13万
  • 项目类别:
Novel Roles for Effector Procaspases
效应器蛋白酶原的新作用
  • 批准号:
    8896823
  • 财政年份:
    2014
  • 资助金额:
    $ 34.13万
  • 项目类别:
Arsenic-induced apoptosis in myeloma
砷诱导骨髓瘤细胞凋亡
  • 批准号:
    7751820
  • 财政年份:
    2009
  • 资助金额:
    $ 34.13万
  • 项目类别:
Arsenic-induced apoptosis in myeloma
砷诱导骨髓瘤细胞凋亡
  • 批准号:
    8386638
  • 财政年份:
    2009
  • 资助金额:
    $ 34.13万
  • 项目类别:

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