Pharmacology and Molecular Sciences Training Program

项目摘要 药理学领域对美国民众的健康和护理有直接影响。位于 约翰霍普金斯大学医学院药理学和分子科学系(DPMS) 在广泛的药理学领域提供卓越的职业培训。的训练任务 药理学和分子科学(PMS)培训计划的核心是为学员提供国家- 最先进的研究知识和专业技能，专注于药物设计、作用机制和 发展和翻译的过程。我们的广泛目标是培养一批不同的初出茅庐的科学家- 学者从事各种药理学相关职业。本计划的课程和活动具体包括 旨在提供涵盖药物发现和开发流程的每个组成部分的培训，并 培养积极的培训经历。我们通过许多旨在实现这一目标的活动实现这一目标 培养学员的核心能力，为药理学的职业生涯做好准备。除了被指导之外 实验室研究，我们的计划有四个培训部分：1)专业和广泛的课程工作在 基础和临床药理学、生理学、生物有机化学、药物发现和生物医学领域 科学，2)与利伯大脑开发研究所(LIBD)的合作关系，这使学生接触到 翻译生物技术研究环境和临床药理学分部，提供以下方面的培训 临床和翻译药理学领域，3)以多方面药理学为重点的职业建设和 通过我们广泛的校友和药业职业关系和机构开展的网络活动 资源，以及4)负责任地进行研究和研究的与药理学有关的多方面培训 在整个培训过程中不断提高重现性的方法。通过以上计划，我们为实习生们做好了准备 拥有必要的知识基础、技术和专业技能，才能在广泛的 药理学。我们在实现这些目标方面的成功将通过经过验证的评估来衡量 工具涵盖课程、培训活动、博士学位委员会口试/笔试以及通过外部考试 评论。重要的是，我们努力为我们的学员提供一条途径，让他们获得使他们能够实现的技能 平衡工作和生活，并在他们选择的职业道路上积极影响社会。该计划打算招聘 并每年保留9名新学员，他们在第一年的培训中将获得这笔培训补助金。 在他们随后几年的指导研究中，他们将得到我们资金充足和多样化的培训的支持 教职员工。该计划旨在为所有受训人员(约5年)提供适当的时间到学位支持。我们提供 一个独特的专注于药理学的职业和职业发展课程和环境， 学员具备适应不断变化的生物医学研究环境的技能，并直接为入职提供便利 进入与药理学相关的广泛职业道路。

Project Summary The field of pharmacology has a direct impact on the health and care of the U.S. population. Located at The Johns Hopkins University School of Medicine, the Department of Pharmacology and Molecular Sciences (DPMS) is well-positioned to provide superb career training in the broad field of Pharmacology. The training mission of the Pharmacology and Molecular Sciences (PMS) Training Program is centered on providing trainees with state- of-the-art research knowledge and professional skills focused on drug design, mechanism of action and the process of development and translation. Our broad objective is to prepare a diverse pool of budding scientist- scholars for a variety of pharmacology-related careers. The Program curriculum and activities are specifically designed to provide training that covers each component of the drug discovery and development pipeline and to nurture a positive training experience. We accomplish this objective through numerous activities designed to develop trainee core competencies and preparation for careers in pharmacology. In addition to mentored laboratory research, our program has four training components: 1) specialized and broad coursework in the areas of basic and clinical pharmacology, physiology, bioorganic chemistry, drug discovery and biomedical sciences, 2) collaborative ties to the Lieber Institute for Brain Development (LIBD), which exposes students to a translational biotech research environment, and the Division of Clinical Pharmacology, which offers training in the areas of clinical and translational pharmacology, 3) multi-faceted pharmacology-focused career building and networking activities through our extensive alumni and pharmaceutical career connections and institutional resources, and 4) multi-faceted pharmacology-related training in the responsible conduct of research and methods to enhance reproducibility that are ongoing throughout training. With the above plan we arm our trainees with the requisite knowledge base, technical and professional skills needed to be successful in the broad field of pharmacology. Our success in achieving these objectives will be measured through validated assessment instruments covering the courses, training activities, Doctorate Board Oral/Written Exams, and through external reviews. Importantly, we strive to provide a pathway for our trainees to attain skills that allow them to achieve work-life balance and to positively impact society in their chosen career paths. The Program intends to recruit and retain nine new trainees each year who will be supported by this training grant for their first year of training. In their subsequent years of mentored research, they will be supported by our well-funded and diverse training faculty. The Program is structured to support appropriate time-to-degree for all trainees (~5 years). We provide a unique pharmacology-focused career and professional development curriculum and environment that arms trainees with the skills to adapt to an ever-changing biomedical research landscape and directly facilitates entry into a broad spectrum of pharmacology-related career paths.