Pharmacology and Molecular Sciences Training Program

项目摘要 药理学领域对美国人口的健康和护理有直接影响。位于 约翰霍普金斯大学医学院药理学和分子科学系（DPMS） 在药理学的广泛领域提供一流的职业培训。训练使命 药理学和分子科学（PMS）培训计划的重点是为学员提供国家， 最先进的研究知识和专业技能，重点是药物设计，作用机制和 发展和翻译的过程。我们的主要目标是培养一批多样化的初露头角的科学家- 学者为各种药理学相关的职业。该计划的课程和活动是具体的 旨在提供涵盖药物发现和开发管道每个组成部分的培训， 培养积极的培训经验。我们通过各种活动来实现这一目标， 培养学员的核心能力，为药理学职业生涯做好准备。除了指导 实验室研究，我们的计划有四个培训组成部分：1）专业和广泛的课程， 基础和临床药理学，生理学，生物有机化学，药物发现和生物医学领域 科学，2）与利伯大脑发育研究所（LIBD）的合作关系，该研究所使学生接触到 转化生物技术研究环境，以及提供以下培训的临床药理学部门 临床和转化药理学领域，3）多方面的药理学为重点的职业建设， 通过我们广泛的校友和制药职业联系和机构的网络活动 资源，以及4）在负责任的研究行为中进行多方面的药理学相关培训， 方法，以提高再现性，正在整个培训。通过上述计划，我们武装我们的学员 具有必要的知识基础，技术和专业技能，需要在广泛的领域取得成功， 药理学我们在实现这些目标方面的成功将通过经过验证的评估来衡量 包括课程，培训活动，博士学位委员会口头/书面考试的文书，并通过外部 评论.重要的是，我们努力为我们的学员提供一个途径，以获得技能，使他们能够实现 工作与生活的平衡，并在他们选择的职业道路上对社会产生积极影响。该计划旨在招募 并每年保留九名新学员，他们在首年的培训课程中会获得培训津贴资助。 在他们随后几年的指导研究中，他们将得到我们资金充足和多样化的培训的支持 教师。该计划旨在为所有学员提供适当的学位时间（约5年）。我们提供 一个独特的药理学为重点的职业和专业发展课程和环境，武器 具有适应不断变化的生物医学研究环境的技能的学员，并直接促进进入 进入广泛的药理学相关的职业道路。

Project Summary The field of pharmacology has a direct impact on the health and care of the U.S. population. Located at The Johns Hopkins University School of Medicine, the Department of Pharmacology and Molecular Sciences (DPMS) is well-positioned to provide superb career training in the broad field of Pharmacology. The training mission of the Pharmacology and Molecular Sciences (PMS) Training Program is centered on providing trainees with state- of-the-art research knowledge and professional skills focused on drug design, mechanism of action and the process of development and translation. Our broad objective is to prepare a diverse pool of budding scientist- scholars for a variety of pharmacology-related careers. The Program curriculum and activities are specifically designed to provide training that covers each component of the drug discovery and development pipeline and to nurture a positive training experience. We accomplish this objective through numerous activities designed to develop trainee core competencies and preparation for careers in pharmacology. In addition to mentored laboratory research, our program has four training components: 1) specialized and broad coursework in the areas of basic and clinical pharmacology, physiology, bioorganic chemistry, drug discovery and biomedical sciences, 2) collaborative ties to the Lieber Institute for Brain Development (LIBD), which exposes students to a translational biotech research environment, and the Division of Clinical Pharmacology, which offers training in the areas of clinical and translational pharmacology, 3) multi-faceted pharmacology-focused career building and networking activities through our extensive alumni and pharmaceutical career connections and institutional resources, and 4) multi-faceted pharmacology-related training in the responsible conduct of research and methods to enhance reproducibility that are ongoing throughout training. With the above plan we arm our trainees with the requisite knowledge base, technical and professional skills needed to be successful in the broad field of pharmacology. Our success in achieving these objectives will be measured through validated assessment instruments covering the courses, training activities, Doctorate Board Oral/Written Exams, and through external reviews. Importantly, we strive to provide a pathway for our trainees to attain skills that allow them to achieve work-life balance and to positively impact society in their chosen career paths. The Program intends to recruit and retain nine new trainees each year who will be supported by this training grant for their first year of training. In their subsequent years of mentored research, they will be supported by our well-funded and diverse training faculty. The Program is structured to support appropriate time-to-degree for all trainees (~5 years). We provide a unique pharmacology-focused career and professional development curriculum and environment that arms trainees with the skills to adapt to an ever-changing biomedical research landscape and directly facilitates entry into a broad spectrum of pharmacology-related career paths.