Core G - Biostatistics

项目摘要/摘要 生物统计核心(核心G)的任务是确保CFAR进行的所有研究 研究人员使用最佳方法进行研究设计和分析；开发创新的新方法 解决方法上的现有差距；扩大从事艾滋病毒研究的量化研究人员的数量 研究；支持跨学科和国际合作；并通过合作确保 培训和指导，CFAR研究人员对与以下方面相关的原则有坚实的知识基础 研究设计、数据分析和解释。核心将继续提供不可或缺的统计数据 许多艾滋病毒/艾滋病研究人员无法获得的支持和协作专业知识，这 将导致资助的艾滋病毒研究和教师招聘的显著扩大。随着波士顿的加入 大学，核心汇集了一支经验丰富的生物统计学家团队，其中包括几名高级教员 在生物统计学方法方面有良好的记录，并在基础科学方面有广泛的知识 以及艾滋病毒/艾滋病研究中的临床问题。该核心将加强其在临床试验、艾滋病毒/结核病联合治疗方面的专业知识 感染和物质使用/艾滋病毒，以及在遗传学和基因组学方面增加了新的专业知识。此外，核心 将能够在与设在波士顿的CFAR调查人员合作中优化其效率和效力。 核心G将继续履行其作为统计专门知识中心的基本使命，继续支持， 培训并与CFAR调查人员合作，进行基础、翻译和临床艾滋病毒研究。 最终，拥有这支杰出的艾滋病毒/艾滋病生物统计学家团队将促进持续的卓越、影响、 从普罗维登斯-波士顿CFAR产生的研究的持久性。 生物统计学是高质量艾滋病毒/艾滋病研究的重要组成部分。核心G将继续提供 不可或缺的统计支持和协作专业知识，否则许多人将无法获得这些支持和专业知识 艾滋病毒/艾滋病研究人员，这将导致资助的艾滋病毒研究和教师招聘的显著扩大。 核心将加强其在研究设计和统计分析方面的广泛专业知识，并增加新的专业知识 在遗传学和基因组学方面。核心G将继续履行其作为统计专门知识中心的基本使命 通过继续支持、培训CFAR调查人员并与其合作，进行基础、翻译和 艾滋病毒临床研究。

Project Summary/Abstract The mission of the Biostatistics Core (Core G) is to ensure that all research undertaken by CFAR investigators uses optimal methods for study design and analysis; to develop innovative new approaches that address existing gaps in methodology; to expand the number of quantitative researchers engaging in HIV research; to support interdisciplinary and international collaborations; and to ensure, through collaboration, training and mentoring, that CFAR researchers have a strong base of knowledge about principles related to study design, data analysis, and interpretation. The Core will continue to provide indispensable statistical support and collaborative expertise that would otherwise not be available to many HIV/AIDS researchers, which will lead to the significant expansion of funded HIV research and faculty hiring. With the addition of Boston University, the Core brings together a team of highly experienced biostatisticians, including several senior faculty with strong track records in biostatistical methods and who have extensive knowledge in underlying scientific and clinical issues in HIV/AIDS research. The core will strengthen its expertise in clinical trials, HIV/TB co- infection, and substance use/HIV as well as add new expertise in genetics and genomics. In addition, the Core will be able to optimize its efficiency and effectiveness in collaborating with CFAR investigators based in Boston. Core G will continue in its basic mission of serving as a locus of statistical expertise by continuing to support, train, and collaborate with CFAR investigators conducting basic, translational, and clinical HIV research. Ultimately, having this outstanding team of HIV/AIDS biostatisticians will promote continued excellence, impact, and durability of the research generated from the Providence-Boston CFAR. Biostatistics is a critical component of high quality HIV/AIDS research. Core G will continue to provide indispensable statistical support and collaborative expertise that would otherwise not be available to many HIV/AIDS researchers, which will lead to the significant expansion of funded HIV research and faculty hiring. The Core will strengthen its extensive expertise in study design and statistical analyses and add new expertise in genetics and genomics. Core G will continue in its basic mission of serving as a locus of statistical expertise by continuing to support, train, and collaborate with CFAR investigators conducting basic, translational, and clinical HIV research.