Brown Moi Partnership for Biostatistics Training in HIV-NAMBARI

项目摘要 肯尼亚和撒哈拉以南非洲的艾滋病毒研究议程意义深远。大部分都是 与美国、加拿大和欧洲的机构合作开发和实施， 在基础设施和科学家和医生的专业发展方面提高地方能力。一 能力建设仍然滞后的重要领域是生物统计学和定量科学：非洲 生物统计学家在国际研究团队中的代表性严重不足，许多艾滋病毒研究 SSA的计划继续依赖于来自全球北方的合作伙伴来实施先进的 设计和分析方法。尽管过去5年在研究和 教育能力，许多领先的大学在撒哈拉以南非洲才开始发展研究生水平的培训， 卫生研究统计。肯尼亚的统计培训通常是理论性的， 主要侧重于生物统计学和农业统计的工作。 肯尼亚第二大大学莫伊大学在这方面具有典型意义。在培训的第一阶段， 计划，莫伊开始实施研究生生物统计学课程的过程。然而，只有 两名教师在莫伊与博士在生物统计学，强调需要扩大现有教师的专业知识 和潜在的新教师的发展。在健康科学学院， 对硕士一级统计人员从事外部供资研究的需求很高。最后，少数 在撒哈拉以南非洲艾滋病毒研究中心工作的受过高级培训的非洲统计学家往往在地理上 与同龄人隔绝，限制了专业发展和交流思想的机会。 拟议的培训计划将通过启动伙伴关系的第二阶段来满足这些需求 在莫伊大学和布朗大学之间该计划将扩大艾滋病毒相关领域的研究和课程能力， 生物统计学和先进的定量方法在莫伊和奠定了基础，在这一领域的可持续发展 通过实现以下具体目标：（1）在布朗提供硕士水平的培训（2名学员，2年 在莫伊和布朗的三明治项目中接受博士培训（2名学员，每人4年），以及博士后培训 在布朗和莫伊（2名受训人员，各2年;（2）促进生物统计学课程的修订和扩展 通过教师发展和教师奖学金（4名学员，每人1年）在Moi;（3）继续每年 在Moi举办的先进生物统计方法讲习班，将提供短期培训和持续的专业培训， 整个SSA的教师和专业人员的发展活动;和（4）奠定基础， Moi大学校园内的健康数据科学中心。 本提案直接借鉴了伙伴关系第一阶段的成就和经验， 培训了6名肯尼亚统计人员、4名硕士生、1名教员和1名研究员。 六名受训人员中有四人在Moi或Eldoret的AMPATH工作，一人正在攻读生物统计学博士学位。

Project summary The HIV research agenda in Kenya and sub-Saharan Africa (SSA) is far-reaching. Much of it has been developed and carried out in partnership with institutions in the United States, Canada, and Europe, leading to gains in local capacity in terms infrastructure and professional development of scientists and physicians. One important domain where capacity building still lags behind is biostatistics and quantitative sciences: African biostatisticians are severely under-represented in international research teams, and many HIV research programs in SSA continue to rely on their partners from the Global North for implementation of advanced methods for design and analysis. Although the past 5 years have seen substantial advances in research and educational capacity, many leading universities in SSA are only beginning to develop graduate-level training in statistics for health research. Statistics training in Kenya has typically been theoretical in nature, with applied work focusing primarily on biometry and agricultural statistics. Moi University, the second largest in Kenya, is typical in this regard. During Phase 1 of this training program, Moi began the process of implementing a graduate biostatistics curriculum. However there are only two faculty at Moi with PhD in biostatistics, highlighting the need for expansion of expertise among current faculty and development of potential new faculty members. At the College of Health Sciences, there continues to be high demand for masters-level statisticians to engage in externally funded research. Finally, the small number of African statisticians with advanced training working in HIV research centers in SSA tend to be geographically isolated from their peers, limiting opportunities for professional development and exchange of ideas. The proposed training program will respond to these needs by launching Phase 2 of a partnership between Moi and Brown Universities. The program will expand research and curricular capacity in HIV-related biostatistics and advanced quantitative methods at Moi and lay the foundation for sustainable growth in this field by accomplishing the following Specific Aims: (1) provide masters-level training at Brown (2 trainees, 2 years each), PhD training in a sandwich program at Moi and Brown (2 trainees, 4 years each), and postdoctoral training at Brown and Moi (2 trainees, 2 years each; (2) facilitate revision and expansion of the biostatistics curriculum at Moi through faculty development and faculty fellowships (4 trainees, 1 year each); (3) continue an annual workshop on advanced biostatistical methods at Moi that will offer short-term training and ongoing professional development activities for faculty members and professionals throughout SSA; and (4) lay the groundwork for a Center for Health Data Science on the campus of Moi University. This proposal builds directly upon the accomplishments and experiences from Phase 1 of the partnership, which provided training to 6 Kenyan statisticians; 4 masters students, 1 faculty fellow and 1 research fellow. Four of the six trainees are working at Moi or AMPATH in Eldoret, and one is pursuing a PhD in biostatistics.