Brown Moi Partnership for Biostatistics Training in HIV-NAMBARI

项目总结 肯尼亚和撒哈拉以南非洲(SSA)的艾滋病毒研究议程影响深远。其中很大一部分是 与美国、加拿大和欧洲的机构合作开发和实施，导致 在科学家和医生的基础设施和专业发展方面提高当地能力。一 能力建设仍然滞后的重要领域是生物统计和量化科学：非洲 生物统计学家在国际研究团队中的代表性严重不足，许多艾滋病毒研究 SSA中的计划继续依赖其来自全球北方的合作伙伴实施高级 设计和分析的方法。尽管在过去的5年里，研究和研究取得了实质性进展 在教育能力方面，SSA的许多顶尖大学才刚刚开始发展研究生水平的培训 卫生研究的统计数据。肯尼亚的统计培训通常是理论性质的，并已应用 主要集中在生物统计学和农业统计方面的工作。 肯尼亚第二大大学莫伊大学在这方面是典型的。在本培训的第1阶段 计划期间，教育部开始了实施生物统计学研究生课程的进程。然而，只有 教育部两名拥有生物统计学博士学位的教员，强调了在现有教员中扩大专业知识的必要性 和发展潜在的新教职员工。在健康科学学院，继续有 对从事外部资助研究的硕士水平的统计学家的需求很高。最后，一小部分人 在南非艾滋病研究中心工作的受过高级培训的非洲统计学家中，往往有地理上的 与同龄人隔绝，限制了职业发展和思想交流的机会。 拟议的培训方案将通过启动伙伴关系第二阶段来回应这些需求 在莫伊大学和布朗大学之间。该计划将扩大与艾滋病毒相关的研究和课程能力 生物统计学和先进的定量方法，为该领域的可持续发展奠定了基础 通过实现以下具体目标：(1)在布朗大学提供硕士级别的培训(2名实习生，2年 每个人)，莫伊和布朗大学三明治项目的博士培训(两名实习生，每人4年)，以及博士后培训 在Brown和Moi(2名实习生，各2年；(2)协助修订和扩展生物统计学课程 在教育部通过教师发展和教师奖学金(4名实习生，每人1年)；(3)继续每年 在教育部举办的高级生物统计方法研讨会，将提供短期培训和持续的专业培训 为整个SSA的教职员工和专业人员开展的发展活动；以及(4)为 位于莫伊大学校园内的健康数据科学中心。 这项提议直接建立在伙伴关系第一阶段的成就和经验基础上， 它为6名肯尼亚统计员、4名硕士研究生、1名教员研究员和1名研究员提供了培训。 六名学员中有四名在埃尔多雷特的MOI或AMPATH工作，一名正在攻读生物统计学博士学位。

Project summary The HIV research agenda in Kenya and sub-Saharan Africa (SSA) is far-reaching. Much of it has been developed and carried out in partnership with institutions in the United States, Canada, and Europe, leading to gains in local capacity in terms infrastructure and professional development of scientists and physicians. One important domain where capacity building still lags behind is biostatistics and quantitative sciences: African biostatisticians are severely under-represented in international research teams, and many HIV research programs in SSA continue to rely on their partners from the Global North for implementation of advanced methods for design and analysis. Although the past 5 years have seen substantial advances in research and educational capacity, many leading universities in SSA are only beginning to develop graduate-level training in statistics for health research. Statistics training in Kenya has typically been theoretical in nature, with applied work focusing primarily on biometry and agricultural statistics. Moi University, the second largest in Kenya, is typical in this regard. During Phase 1 of this training program, Moi began the process of implementing a graduate biostatistics curriculum. However there are only two faculty at Moi with PhD in biostatistics, highlighting the need for expansion of expertise among current faculty and development of potential new faculty members. At the College of Health Sciences, there continues to be high demand for masters-level statisticians to engage in externally funded research. Finally, the small number of African statisticians with advanced training working in HIV research centers in SSA tend to be geographically isolated from their peers, limiting opportunities for professional development and exchange of ideas. The proposed training program will respond to these needs by launching Phase 2 of a partnership between Moi and Brown Universities. The program will expand research and curricular capacity in HIV-related biostatistics and advanced quantitative methods at Moi and lay the foundation for sustainable growth in this field by accomplishing the following Specific Aims: (1) provide masters-level training at Brown (2 trainees, 2 years each), PhD training in a sandwich program at Moi and Brown (2 trainees, 4 years each), and postdoctoral training at Brown and Moi (2 trainees, 2 years each; (2) facilitate revision and expansion of the biostatistics curriculum at Moi through faculty development and faculty fellowships (4 trainees, 1 year each); (3) continue an annual workshop on advanced biostatistical methods at Moi that will offer short-term training and ongoing professional development activities for faculty members and professionals throughout SSA; and (4) lay the groundwork for a Center for Health Data Science on the campus of Moi University. This proposal builds directly upon the accomplishments and experiences from Phase 1 of the partnership, which provided training to 6 Kenyan statisticians; 4 masters students, 1 faculty fellow and 1 research fellow. Four of the six trainees are working at Moi or AMPATH in Eldoret, and one is pursuing a PhD in biostatistics.