权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Investigating Medication Errors in Daily Life: Discovering Person-specific and Situation-specific Risk Factors

调查日常生活中的用药错误：发现特定于个人和特定情况的风险因素

基本信息

批准号：
10202481
负责人：
Nelson Roque
金额：
$ 7.45万
依托单位：
UNIVERSITY OF CENTRAL FLORIDA
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10202481
关键词：
Adult Age Aging Attention Automobile Driving Caregivers Caring Cataract Cellular Phone Cessation of life Chronic Clinic Clinical Clinical Data Cognition Cognitive Collaborations Communities Complex Consumption Data Dementia Disease Dizziness Dose Drug Prescriptions Ecological momentary assessment Ecosystem Educational Intervention Elderly Electronic Health Record Event Frequencies Future Guidelines Health Health care facility Healthcare Healthcare Systems Home Hospitalization Hospitals Incidence Individual Injury Intervention Interview Knowledge Life Literature Litigation Location Long-Term Care Macular degeneration Medication Errors Medication Management Memory Methods Modeling Monitor Nature Neurologist Nurses Outcome Outcome Measure Patient Self-Report Patients Pattern Perception Performance Personal Satisfaction Persons Pharmaceutical Preparations Pharmaceutical Societies Pharmacists Physicians Policies Polypharmacy Predisposition Probability Process Psyche structure Recommendation Recording of previous events Regimen Reporting Research Risk Risk Factors Safety Sampling Sleep disturbances Stress Testing United States Visual Work care providers cognitive change cognitive performance cost diaries distraction empowerment innovation insight instrumental activity of daily living interest medication administration medication compliance mental state mild cognitive impairment novel processing speed recruit scaffold

项目摘要

PROJECT SUMMARY/ABSTRACT In order to maintain independence into late adulthood, one must be able to safely and reliably participate in Instrumental Activities of Daily Living (IADLs), including taking medications for treatment of chronic conditions. The potential to do this safely without making a medication error depends on a multitude of pre-conditions, including: the number of distinct medications consumed, cognitive status (e.g., dementia), the presence of a caregiver or other mental scaffolds (i.e., medication diary), and cognitive vulnerability (e.g., susceptibility to distraction). Medication errors are numerous — over a million yearly injuries and 98,000 deaths — and occur across the spectrum of healthcare (i.e., nurses, physicians, pharmacists, patients), yet little is known about medication errors in daily life. For this R03, we are specifically interested in understanding the types of medication errors made in daily life, and discovering person-specific and situation-specific risk factors for medication errors in the home. Perceptions of medication administration problems, medication regimen complexity, and the nature of medication errors in the home and their consequences will be assessed in older adults currently recruited into the Einstein Aging Study (EAS), using an innovative three-pronged medication assessment (i.e., daily EMA of medication administration problems, medication error history interview with study neurologist, medication possession ratios from EHRs). Making use of existing clinical data (i.e., ratings of MCI), and cognitive performance data (both in-lab and ambulatory assessments) we will identify person-specific and situation-specific risk factors for various types of medication errors. Completion of this work will highlight actionable targets for future interventions targeting the reduction of medication errors.

项目总结/摘要为了在成年后期保持独立性，一个人必须能够安全可靠地参与工具性日常生活活动（IADL），包括服用治疗慢性疾病的药物。安全地做到这一点而不犯用药错误的可能性取决于许多先决条件，包括：消耗的不同药物的数量，认知状态（例如，痴呆症），存在看护者或其他心理支架（即，药物日记），和认知脆弱性（例如，易感性分心）。用药错误是众多的-超过一百万每年受伤和98,000死亡-并发生在医疗保健的范围内（即，护士，医生，药剂师，患者），但对日常生活中的用药错误对于R 03，我们特别感兴趣的是了解日常生活中出现的用药错误，并发现特定于个人和特定于情况的风险因素家里的药物错误。对给药问题、给药方案的看法复杂性，以及家庭用药错误的性质及其后果将在老年人中进行评估。目前，爱因斯坦衰老研究（EAS）招募了一批成年人，他们使用了一种创新的三管齐下的药物，评估（即，每日EMA给药问题、用药错误史与研究访谈神经科医生，来自EHR的药物占有率）。利用现有的临床数据（即，MCI评级），和认知性能数据（包括实验室和门诊评估），我们将确定个人特定的，各种类型用药错误的特定情况风险因素。这项工作的完成将突出未来干预措施的可操作目标，旨在减少用药错误。