Chemistry and Biology Interface (CBI) NIH T32 Training Grant

化学与生物接口 (CBI) NIH T32 培训补助金

• 批准号: 10201665
• 负责人: BRIAN J BAHNSON
• 金额: $ 43.89万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10201665
• 关键词: Biology; Chemistry; Grant; Training; United States National Institutes of Health

The objective of this Chemistry-Biology Interface (CBI) Predoctoral Program is to provide cross-disciplinary training to talented students with diverse interests that will enable them to apply the mechanistic and atomistic perspective of chemistry to important biological problems. The program brings together 42 faculty trainers from eight academic units at the Univ. of Delaware representing disciplines of organic chemistry, analytical chemistry, biochemistry, chemical biology, structural biology, molecular biology, cell biology, systems biology, bioinformatics, molecular biology, cell biology, microbiology, virology, and developmental biology. The faculty trainers include both new and established researchers with vibrant research programs in biomolecular science and experience in training graduate students. A diverse trainee group (with a focus to recruit and retain URMs) with varied educational backgrounds are selected on the basis of their desire to explore multidisciplinary problems at the interface of chemistry and biology, their GRE scores, undergraduate GPA, letters of recommendation and research background. Eight trainees are admitted each year through existing graduate programs of Chemistry & Biochemistry, Chemical & Biomolecular Engineering, Biological Sciences or other CBI trainer departments and university supported for their first year. A second, funded track of admission to the CBI program is outlined; students with a strong interest in research at the interface of chemistry and biology will be invited to apply at the end of their first or second year of their graduate studies. All trainees will satisfy the degree requirements for their specific departmental program in addition to the requirements for the CBI program. Three one semester courses will be selected from a diverse list of course offerings from six departments. A key feature of the CBI program is the laboratory rotations each trainee undertakes to provide them with hands-on experience in the different disciplines. Between courses and laboratory rotations students are expected to have exposure to concepts and methods from the atomistic to the cellular. Students are empowered by this background to think creatively about biological and chemical problems that are relevant to human health. This proposal aims to provide students with a menu of university funded internships (local pharmaceutical/biotech firms, National Labs and new collaborations to enhance their career development. All trainees are required to participate in a series of quarterly responsible conduct of research (RCR) workshops, a 2-day University sponsored RCR and a January workshop of data reproducibility and rigor. A weekly seminar series brings the CBI community together and provides trainees numerous opportunities to present their own work, as well as learn from both faculty trainers and outside speakers. Each trainee undertakes an intensive independent research experience culminating in a dissertation representing an original contribution to a field at the chemistry-biology interface. This program follows and builds on a successful 25-year model for training scientists with both broad scientific knowledge as well as solid foundations in a chosen core discipline.

这个化学-生物学接口（CBI）博士预科课程的目标是提供跨学科的 培训有才华的学生与不同的利益，使他们能够应用机械和原子的 从化学的角度看待重要的生物学问题。该计划汇集了42名教师培训师， 特拉华州大学的八个学术单位，代表有机化学、分析化学、 化学，生物化学，化学生物学，结构生物学，分子生物学，细胞生物学，系统生物学， 生物信息学、分子生物学、细胞生物学、微生物学、病毒学和发育生物学。学院 培训人员包括新的和建立的研究人员，他们在生物分子科学方面有着充满活力的研究项目 培养研究生的经验。多样化的受训者群体（重点是招募和留住URM） 具有不同教育背景的学生是根据他们探索多学科的愿望而选择的。 化学和生物学界面的问题、他们的GRE成绩、本科GPA、信件 建议和研究背景。每年通过现有的毕业生招收8名学员。 化学与生物化学，化学与生物分子工程，生物科学或其他课程 CBI培训师部门和大学支持他们的第一年。第二，资助进入轨道， CBI计划概述;学生对化学和生物学界面的研究有浓厚的兴趣 将被邀请在他们的研究生学习的第一年或第二年结束时申请。所有学员都将满足 除了对CBI的要求外，他们的具体部门计划的学位要求 程序.三个一学期的课程将从六个不同的课程列表中选择 部门CBI计划的一个关键特点是每个受训者承诺提供的实验室轮换 他们在不同学科的实践经验。在课程和实验室轮换学生之间 预计将接触到从原子到细胞的概念和方法。学生 在这种背景下，他们能够创造性地思考与生物和化学有关的问题， 人体健康这项建议旨在为学生提供一个大学资助的实习菜单（当地 制药/生物技术公司，国家实验室和新的合作，以提高他们的职业发展。所有 学员必须参加一系列季度性的负责任研究行为讲习班， 2-戴大学赞助了RCR和一月份的数据再现性和严谨性研讨会。每周一次的研讨会 系列将CBI社区聚集在一起，并为学员提供众多机会，展示他们自己的 工作，以及从教师培训师和外部演讲者那里学习。每一位学员都要进行一次密集的 独立的研究经验，最终在论文中代表了一个领域的原始贡献， 化学与生物学的结合该计划遵循并建立在一个成功的25年的培训模式 科学家既有广泛的科学知识，又有所选核心学科的坚实基础。