NIH Training Grant in Chemistry-Biology Interface

NIH 化学-生物学界面培训补助金

• 批准号: 10410907
• 负责人: KARA L. BREN
• 金额: $ 20.81万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10410907
• 关键词: Biology; Chemistry; Grant; Training; United States National Institutes of Health

PROJECT SUMMARY: The goal of this Chemistry-Biology Interface (CBI) training program is to prepare 10 predoctoral students to become next-generation scientists in the biomedical sciences. This goal will be achieved through recruiting top students and training them in cross-disciplinary research, critical thinking, writing and communication, rigorous experiment design and interpretation, and responsible conduct of research. Other distinctive components of the program are: a) a course on cutting-edge research at the CBI, b) workshops on entrepreneurship, intellectual property management, and networking, and c) participation in Peer-Led Team Learning (PLTL) experiences, which will further enrich the skillset and professional preparation of the trainees. The program will directly benefit from the close research relationship and physical proximity between Arts, Sciences, & Engineering (AS&E) and the School of Medicine and Dentistry (SMD) at the University of Rochester, and its established record in innovation and entrepreneurial translation of scientific discoveries into new businesses. The program includes 27 outstanding preceptors selected from six departments within AS&E and SMD, all of whom have a strong record of intra- and interdepartmental interactions in research and mentoring activities. A central theme of the program, as shared by the research interests of the preceptors, is the development of fundamental knowledge and strategies to support the generation, development, and delivery of new therapeutic agents and modalities for the prevention and treatment of human diseases. Trainees will conduct research in one of the four main areas around this unifying theme: Synthetic Chemistry, Drug Discovery & Delivery, Drug Target Identification and Sensing, and Structure and Function of Biomolecules & Biomaterials. The Program Director and two Deputy Directors will be aided by a Steering Committee comprising three additional faculty members. The CBI trainees will be drawn from the strongest students in the participating departments, with a particular emphasis on expanding trainee diversity through outreach activities, recruiting a diverse pool of applicants, and retaining and nurturing students in the program. New CBI trainees will start in Year 2 of their graduate studies and will participate in the core CBI courses, a course on responsible conduct of research, and a course on effective writing and communication. All trainees will participate and contribute to a host of CBI-sponsored enrichment and synergistic activities, including professional development workshops, an annual retreat, and monthly CBI lunches. In Year 4 of their PhD program, trainees will serve as PLTL workshop leaders for CBI courses, continue in professional development, and present a talk at the CBI retreat. Trainees also will complete and defend their theses supervised by one of the CBI preceptors. It is expected that students completing this program will be exceptionally well prepared to pursue a variety of careers in the life and biomedical sciences. Success in this program will also be determined by increased diversity of trainees and in the pool of applicants.

项目概要：本化学-生物学界面（CBI）培训计划的目标是准备10 博士前学生成为生物医学科学的下一代科学家。这一目标将 通过招募顶尖学生并在跨学科研究，批判性思维， 写作和沟通，严格的实验设计和解释，以及负责任的行为 research.该计划的其他独特组成部分是：a）在CBI的前沿研究课程，B） 关于创业精神、知识产权管理和联网的讲习班，以及c）参加 同行领导的团队学习（PLTL）经验，这将进一步丰富技能和专业准备 的学员。该计划将直接受益于密切的研究关系和物理接近 艺术，科学与工程（AS&E）和医学和牙科学院（SMD）之间的关系 罗切斯特大学，以及它在创新和创业翻译科学 发现新业务。该计划包括27名优秀的导师， AS&E和SMD内的部门，所有这些部门都有部门内和部门间的良好记录。 研究和指导活动中的互动。该计划的一个中心主题，正如研究所分享的那样， 教师的利益，是发展基本知识和战略，以支持 产生、开发和递送新的治疗剂和模式，用于预防和 治疗人类疾病。学员将围绕这一统一的四个主要领域之一进行研究 主题：合成化学，药物发现和递送，药物靶点识别和传感，结构 生物分子和生物材料的功能。项目主任和两名副主任将得到以下人员的协助： 一个指导委员会，由三个额外的教员。CBI的受训人员将从 最强的学生在参与部门，特别强调扩大学员的多样性 通过推广活动，招募不同的申请人，并保留和培养学生在 程序.新的CBI学员将在研究生学习的第二年开始，并将参加核心CBI 一门关于负责任地进行研究的课程，一门关于有效写作和交流的课程。 所有学员将参加并促进一系列由CBI赞助的丰富和协同活动， 包括专业发展研讨会、年度务虚会和每月的CBI午餐。在第四年， 博士课程，学员将担任CBI课程的PLTL研讨会负责人，继续在专业 发展，并在CBI务虚会上发表演讲。学员还将完成并捍卫他们的论文 由CBI校长之一监督。预计完成该计划的学生将 为从事生命和生物医学科学领域的各种职业做好了特别充分的准备。胜任这 该计划还将取决于学员和申请人的多样性增加。